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European Radiology
Published in: European Radiology 5/2007

01-05-2007 | Magnetic Resonance

Intra-individual comparison of image contrast in SPIO-enhanced liver MRI at 1.5T and 3.0T

Authors: Marcus von Falkenhausen, Carsten Meyer, Götz Lutterbey, Nuschin Morakkabati, Oliver Walter, Jürgen Gieseke, Renate Blömer, Winfried A. Willinek, Christiane K. Kuhl, Hans H. Schild

Published in: European Radiology | Issue 5/2007

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Abstract

The purpose of the study was to examine if the higher susceptibility at 3.0 Tesla (T) compared to 1.5 T will affect the contrast in MR imaging of the liver after application of superparamagnetic iron oxide particles (SPIO). The study was approved by our institutional review board and informed consent was obtained. Seventeen healthy volunteers were examined in a prospective, intra-individual comparative study within one day on a 1.5 T and a 3.0 T MRI system. T2 weighted TSE sequences were acquired after bolus injection of a SPIO contrast agent. Image contrast and signal to noise ratio (SNR) were compared between the field strengths. Image contrast was calculated between the liver tissue and the kidneys / spleen / muscles and fluids. The students’T-test was used for statistical analysis. No influence of the higher field strength could be observed on image contrast except for the liver / muscle contrast. This was due to a distinct SNR increase of the muscle tissue at 3.0 T as a result of their relaxation properties. The higher susceptibility at 3.0 T compared to 1.5 T does not translate into a stronger signal attenuation of the SPIO enhanced liver parenchyma.
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Metadata
Title
Intra-individual comparison of image contrast in SPIO-enhanced liver MRI at 1.5T and 3.0T
Authors
Marcus von Falkenhausen
Carsten Meyer
Götz Lutterbey
Nuschin Morakkabati
Oliver Walter
Jürgen Gieseke
Renate Blömer
Winfried A. Willinek
Christiane K. Kuhl
Hans H. Schild
Publication date
01-05-2007
Publisher
Springer-Verlag
Published in
European Radiology / Issue 5/2007
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-006-0484-y

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