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CardioVascular and Interventional Radiology

04-03-2024 | Clinical Investigation

Safety and Efficacy of Percutaneous Morton Neuroma Cryoneurolysis Under Ultrasound Guidance

Authors: Benjamin Moulin, Giorgio Angelopoulos, Jean Luc Sarrazin, Stephane Romano, Olivier Vignaux, Thierry Guenoun, Massimiliano Di Primio, Antoine Hakime

Published in: CardioVascular and Interventional Radiology

Abstract

Purpose

To assess the technical success, safety and early efficacy of Morton neuroma (MN) cryoneurolysis.

Materials and Methods

Retrospective review of 54 consecutive patients with MN treated with cryoneurolysis after failure of conservative treatment, from September 2022 to June 2023. Outcomes measurements included technical success (defined a successful ultrasound-guided placement of the cryoprobe), procedural safety according to Cirse classification and change in 6 months post-procedure by pain numeric rating scale (pNRS).

Results

A total of 59 MN were treated during 55 procedures. Mean procedure duration was 47 min, all patients were discharged 2 h after the intervention. Technical success was 98.1%. No Cirse grade 3, 4 or 5 complication was reported. Three grade 2 complication occurred, including two chilblain-type lesions and one bone insufficiency fracture. At 6 months post-procedure, pNRS score was significantly decreased (2.7 ± 2.2 vs 7.1 ± 1.1) (p < 0.0001), with a mean score decrease of 4.1points. Thirty-two patients (60.4%) reported a complete pain relief, 15 (28.3%) a partial pain relief and 6 (11.3%) no pain relief, or increased pain.

Conclusion

Cryoneurolysis seems to be safe for the treatment of Morton neuroma. Six-month pain relief is promising and needs to be confirmed at long term.

Graphical Abstract

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Title: Safety and Efficacy of Percutaneous Morton Neuroma Cryoneurolysis Under Ultrasound Guidance
Authors: Benjamin Moulin
Giorgio Angelopoulos
Jean Luc Sarrazin
Stephane Romano
Olivier Vignaux
Thierry Guenoun
Massimiliano Di Primio
Antoine Hakime
Publication date: 04-03-2024
Publisher: Springer US
Published in: CardioVascular and Interventional Radiology
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-024-03669-1

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Abstract

Purpose

Materials and Methods

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Conclusion

Graphical Abstract

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