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Published in: CardioVascular and Interventional Radiology 6/2017

01-06-2017 | Clinical Investigation

Efficacy of Preoperative Transcatheter Arterial Embolization for Nasopharyngeal Angiofibroma: A Comparative Study

Authors: Guosheng Tan, Zhenjiang Ma, Weiqing Long, Liangshuai Liu, Bing Zhang, Wei Chen, Jianyong Yang, Heping Li

Published in: CardioVascular and Interventional Radiology | Issue 6/2017

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Abstract

Objective

This study aimed to retrospectively evaluate the efficacy and safety of preoperative transcatheter arterial embolization (pTAE) for treating nasopharyngeal angiofibroma (NPAF).

Methods

Seventy-four NPAF patients were hospitalized for elective surgical treatment with pTAE (pTAE group, n = 32) or surgical treatment alone (non-pTAE group, n = 42) between January 1990 and December 2013. The following outcome measures were retrospectively analyzed and compared: intraoperative bleeding volume, surgery time (ST), duration of postoperative hospital stay (PHS), and disease recurrence.

Results

Among Radkowski stage I patients, those in pTAE group had a slightly higher but not significant bleeding volume than patients in non-pTAE group (344 ± 407 vs. 248 ± 219 mL, P = 0.899); among stage II/III patients, however, patients in pTAE group showed a significantly lower bleeding volume than patients in non-pTAE group (stage II, 829 ± 519 vs. 1339 ± 767 mL, P = 0.035; stage III, 1267 ± 592 vs. 2125  ± 479 mL, P = 0.024). The two groups presented comparable OTs, PHSs, and rates of frontal recurrence (all P>0.05).

Conclusions

pTAE significantly reduces intraoperative bleeding in NPAF patients with Radkowski stage II/III disease, but offers no additional benefits regarding ST, PHS, or recurrence.
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Metadata
Title
Efficacy of Preoperative Transcatheter Arterial Embolization for Nasopharyngeal Angiofibroma: A Comparative Study
Authors
Guosheng Tan
Zhenjiang Ma
Weiqing Long
Liangshuai Liu
Bing Zhang
Wei Chen
Jianyong Yang
Heping Li
Publication date
01-06-2017
Publisher
Springer US
Published in
CardioVascular and Interventional Radiology / Issue 6/2017
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI
https://doi.org/10.1007/s00270-017-1587-3

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