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CardioVascular and Interventional Radiology

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01-06-2012 | Technical Note

Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations

Authors: Stephanie G. C. Kroeze, Merel Huisman, Helena M. Verkooijen, Paul J. van Diest, J. L. H. Ruud Bosch, Maurice A. A. J. van den Bosch

Published in: CardioVascular and Interventional Radiology | Issue 3/2012

Abstract

Introduction

Three-dimensional (3D) real-time fluoroscopy cone beam CT is a promising new technique for image-guided biopsy of solid tumors. We evaluated the technical feasibility, diagnostic accuracy, and complications of this technique for guidance of large-core needle biopsy in patients with suspicious renal masses.

Methods

Thirteen patients with 13 suspicious renal masses underwent large-core needle biopsy under 3D real-time fluoroscopy cone beam CT guidance. Imaging acquisition and subsequent 3D reconstruction was done by a mobile flat-panel detector (FD) C-arm system to plan the needle path. Large-core needle biopsies were taken by the interventional radiologist. Technical success, accuracy, and safety were evaluated according to the Innovation, Development, Exploration, Assessment, Long-term study (IDEAL) recommendations.

Results

Median tumor size was 2.6 (range, 1.0–14.0) cm. In ten (77%) patients, the histological diagnosis corresponded to the imaging findings: five were malignancies, five benign lesions. Technical feasibility was 77% (10/13); in three patients biopsy results were inconclusive. The lesion size of these three patients was <2.5 cm. One patient developed a minor complication. Median follow-up was 16.0 (range, 6.4–19.8) months.

Conclusions

3D real-time fluoroscopy cone beam CT-guided biopsy of renal masses is feasible and safe. However, these first results suggest that diagnostic accuracy may be limited in patients with renal masses <2.5 cm.

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Title: Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations
Authors: Stephanie G. C. Kroeze
Merel Huisman
Helena M. Verkooijen
Paul J. van Diest
J. L. H. Ruud Bosch
Maurice A. A. J. van den Bosch
Publication date: 01-06-2012
Publisher: Springer-Verlag
Published in: CardioVascular and Interventional Radiology / Issue 3/2012
Print ISSN: 0174-1551
Electronic ISSN: 1432-086X
DOI: https://doi.org/10.1007/s00270-011-0237-4

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Real-Time 3D Fluoroscopy-Guided Large Core Needle Biopsy of Renal Masses: A Critical Early Evaluation According to the IDEAL Recommendations

Abstract

Introduction

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Introduction

Methods

Results

Conclusions

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