Skip to main content
Top
Published in: World Journal of Surgery 12/2023

Open Access 25-09-2023 | Appendectomy | Scientific Review

Factors Contributing to Delays to Accessing Appendectomy in Low- and Middle-Income Countries: A Scoping Review

Authors: Johnelize Louw, M. McCaul, R. English, P. S. Nyasulu, J. Davies, C. Fourie, J. Jassat, K. M. Chu

Published in: World Journal of Surgery | Issue 12/2023

Login to get access

Abstract

Background

Appendicitis is one of the most common emergency surgical conditions worldwide. Delays in accessing appendectomy can lead to complications. Evidence on these delays in low- and middle-income countries (LMICs) is lacking. The aim of this review was to identify and synthesise the available evidence on delays to accessing appendectomy in LMICs.

Methods

This scoping review followed the Preferred Reporting Items for Systematic Reviews and Meta-analysis Extension for Scoping Reviews framework. The delays and their interconnectivity in LMICs were synthesised and interpreted using the Three Delays framework. We reviewed Africa Wide EBSCOhost, PubMed–Medline, Scopus, Web of Science, African Journals Online (AJOL), and Bioline databases.

Results

Our search identified 21 893 studies, of which 78 were included in the final analysis. All of the studies were quantitative. Fifty per cent of the studies included all three types of delays. Delays in seeking care were influenced by a lack of awareness of appendicitis symptoms, and the use of self and alternative medication, which could be linked to delays in receiving care, and the barrier refusal of medical treatment due to fear. Financial concerns were a barrier observed throughout the care pathway.

Conclusion

This review highlighted the need for additional studies on delays to accessing appendectomy in additional LMICs. Our review demonstrates that in LMICs, persons seeking appendectomy present late to health-care facilities due to several patient-related factors. After reaching a health-care facility, accessing appendectomy can further be delayed owing to a lack of adequate hospital resources.
Appendix
Available only for authorised users
Literature
1.
go back to reference Meara JG, Leather AJM, Hagander L et al (2015) Global Surgery 2030: Evidence and solutions for achieving health, welfare, and economic development. The Lancet 386(9993):569–624CrossRef Meara JG, Leather AJM, Hagander L et al (2015) Global Surgery 2030: Evidence and solutions for achieving health, welfare, and economic development. The Lancet 386(9993):569–624CrossRef
3.
go back to reference Chamisa I (2009) A clinicopathological review of 324 appendices removed for acute appendicitis in Durban, South Africa: a retrospective analysis. Ann R Coll Surg Engl 91(8):688–692PubMedPubMedCentralCrossRef Chamisa I (2009) A clinicopathological review of 324 appendices removed for acute appendicitis in Durban, South Africa: a retrospective analysis. Ann R Coll Surg Engl 91(8):688–692PubMedPubMedCentralCrossRef
4.
go back to reference Busch M, Gutzwiller FS, Aellig S et al (2011) In-hospital delay increases the risk of perforation in adults with appendicitis. World J Surg 35(7):1626–1633PubMedCrossRef Busch M, Gutzwiller FS, Aellig S et al (2011) In-hospital delay increases the risk of perforation in adults with appendicitis. World J Surg 35(7):1626–1633PubMedCrossRef
7.
go back to reference Salminen P, Paajanen H, Rautio T et al (2015) Antibiotic therapy vs appendectomy for treatment of uncomplicated acute appendicitis: the APPAC randomized clinical trial. JAMA 313(23):2340–2348PubMedCrossRef Salminen P, Paajanen H, Rautio T et al (2015) Antibiotic therapy vs appendectomy for treatment of uncomplicated acute appendicitis: the APPAC randomized clinical trial. JAMA 313(23):2340–2348PubMedCrossRef
8.
go back to reference Thaddeus S, Maine D (1994) Too far to walk: maternal mortality in context. Soc Sci Med 38(8):1091–1110PubMedCrossRef Thaddeus S, Maine D (1994) Too far to walk: maternal mortality in context. Soc Sci Med 38(8):1091–1110PubMedCrossRef
9.
go back to reference Calvello EJ, Skog AP, Tenner AG et al (2015) Applying the lessons of maternal mortality reduction to global emergency health. Bull World Health Organ 93(6):417–423PubMedPubMedCentralCrossRef Calvello EJ, Skog AP, Tenner AG et al (2015) Applying the lessons of maternal mortality reduction to global emergency health. Bull World Health Organ 93(6):417–423PubMedPubMedCentralCrossRef
10.
go back to reference Anto-Ocrah M, Cushman J, Sanders M et al (2020) A woman’s worth: An access framework for integrating emergency medicine with maternal health to reduce the burden of maternal mortality in sub-Saharan Africa. BMC Emerg Med 20(1):1–8CrossRef Anto-Ocrah M, Cushman J, Sanders M et al (2020) A woman’s worth: An access framework for integrating emergency medicine with maternal health to reduce the burden of maternal mortality in sub-Saharan Africa. BMC Emerg Med 20(1):1–8CrossRef
11.
go back to reference Tricco AC, Lillie E, Zarin W et al (2018) PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med 169:467–473PubMedCrossRef Tricco AC, Lillie E, Zarin W et al (2018) PRISMA extension for scoping reviews (PRISMA-ScR): checklist and explanation. Ann Intern Med 169:467–473PubMedCrossRef
12.
go back to reference Arksey H, O’Malley L (2005) Scoping studies: Towards a methodological framework. Int J Soc Res Methodol 8(1):19–32CrossRef Arksey H, O’Malley L (2005) Scoping studies: Towards a methodological framework. Int J Soc Res Methodol 8(1):19–32CrossRef
13.
go back to reference Tricco AC, Lillie E, Zarin W et al (2016) A scoping review on the conduct and reporting of scoping reviews. BMC Med Res Methodol 16(1):1–10CrossRef Tricco AC, Lillie E, Zarin W et al (2016) A scoping review on the conduct and reporting of scoping reviews. BMC Med Res Methodol 16(1):1–10CrossRef
14.
go back to reference Abantanga FA, Nimako B, Amoah M (2009) The range of abdominal surgical emergencies in children older than 1 year at the Komfo Anokye Teaching Hospital, Kumasi. Ghana Ann Afr Med 8(4):236–242PubMedCrossRef Abantanga FA, Nimako B, Amoah M (2009) The range of abdominal surgical emergencies in children older than 1 year at the Komfo Anokye Teaching Hospital, Kumasi. Ghana Ann Afr Med 8(4):236–242PubMedCrossRef
15.
go back to reference Afenigus AD, Bayieh AM, Kassahun B (2020) Treatment outcomes of acute appendicitis and associated factors among admitted patients with a diagnosis of acute abdomen in Debre Markos Referral Hospital, Amhara Region. North West Ethiopia J Perioper Pract 32(5):123–130PubMed Afenigus AD, Bayieh AM, Kassahun B (2020) Treatment outcomes of acute appendicitis and associated factors among admitted patients with a diagnosis of acute abdomen in Debre Markos Referral Hospital, Amhara Region. North West Ethiopia J Perioper Pract 32(5):123–130PubMed
16.
go back to reference Agholor K, Omo-Aghoja L, Okonofua F (2011) Rate of negative appendectomy in pregnant women in Benin City. Nigeria J Obstet Gynaecol Res 37(11):1540–1548PubMedCrossRef Agholor K, Omo-Aghoja L, Okonofua F (2011) Rate of negative appendectomy in pregnant women in Benin City. Nigeria J Obstet Gynaecol Res 37(11):1540–1548PubMedCrossRef
17.
go back to reference Ahmad KA, Ideris N, Abd Aziz SHS (2019) A cross-sectional study of neutrophilto- lymphocyte ratio in diagnosing acute appendicitis in hospital Melaka. Malays J Med Sci 26(6):55–66PubMedPubMedCentral Ahmad KA, Ideris N, Abd Aziz SHS (2019) A cross-sectional study of neutrophilto- lymphocyte ratio in diagnosing acute appendicitis in hospital Melaka. Malays J Med Sci 26(6):55–66PubMedPubMedCentral
18.
go back to reference Akhator A (2012) Appendicitis in the elderly-experience from Nigeria. Biosci Biotechnol Res Asia 9(2):717–719CrossRef Akhator A (2012) Appendicitis in the elderly-experience from Nigeria. Biosci Biotechnol Res Asia 9(2):717–719CrossRef
19.
go back to reference Asad S, Ahmed A, Ahmad S et al (2015) Causes of delayed presentation of acute appendicitis and its impact on morbidity and mortality. J Ayub Med Coll Abbottabad 27(3):620–623PubMed Asad S, Ahmed A, Ahmad S et al (2015) Causes of delayed presentation of acute appendicitis and its impact on morbidity and mortality. J Ayub Med Coll Abbottabad 27(3):620–623PubMed
20.
go back to reference Avci V, Ayengin K (2019) Why is the rate of perforated appendicitis higher in girls in eastern Turkey, unlike the literature? Turk Pediatri Arsivi 54(1):40–43PubMedPubMedCentral Avci V, Ayengin K (2019) Why is the rate of perforated appendicitis higher in girls in eastern Turkey, unlike the literature? Turk Pediatri Arsivi 54(1):40–43PubMedPubMedCentral
21.
go back to reference Ayoade AB, Olawoye OA, Salami BA et al (2006) Acute appendicitis in Olabisi Onabajo University teaching Hospital Sagamu, A three year review. Niger J Clin Pract 9(1):52–56PubMed Ayoade AB, Olawoye OA, Salami BA et al (2006) Acute appendicitis in Olabisi Onabajo University teaching Hospital Sagamu, A three year review. Niger J Clin Pract 9(1):52–56PubMed
22.
go back to reference Azoz M, Elhaj M (2009) Appendicitis in children: audit of outcome in kosti-teaching hospital. SJMS 4(4) Azoz M, Elhaj M (2009) Appendicitis in children: audit of outcome in kosti-teaching hospital. SJMS 4(4)
23.
go back to reference Bagguley D, Fordyce A, Guterres J et al (2019) Access delays to essential surgical care using the Three Delays Framework and Bellwether procedures at Timor Leste’s national referral hospital. BMJ Open 9(8):1–5CrossRef Bagguley D, Fordyce A, Guterres J et al (2019) Access delays to essential surgical care using the Three Delays Framework and Bellwether procedures at Timor Leste’s national referral hospital. BMJ Open 9(8):1–5CrossRef
24.
go back to reference Bekele A, Mekasha A (2006) Clinical profile and risk factors for perforation of acute appendicitis in children. East Afr Med J 83(8):434–439PubMedCrossRef Bekele A, Mekasha A (2006) Clinical profile and risk factors for perforation of acute appendicitis in children. East Afr Med J 83(8):434–439PubMedCrossRef
25.
go back to reference Doumi EA, Abdelrahman IH (2007) Acute appendicitis: still a missed diagnosis in El Obeid. Western Sudan SJMS 2(1):7–8 Doumi EA, Abdelrahman IH (2007) Acute appendicitis: still a missed diagnosis in El Obeid. Western Sudan SJMS 2(1):7–8
26.
go back to reference Doumi EA, Manofali OE (2014) Appendicular mass at El Obeid Hospital. Western Sudan SJMS 9(3):183–186 Doumi EA, Manofali OE (2014) Appendicular mass at El Obeid Hospital. Western Sudan SJMS 9(3):183–186
27.
go back to reference Duduyemi BM (2015) Clinicopathological review of surgically removed appendix in Central Nigeria, Alexandria. J Med 51(3):207–211 Duduyemi BM (2015) Clinicopathological review of surgically removed appendix in Central Nigeria, Alexandria. J Med 51(3):207–211
29.
go back to reference Kumaira Fonseca M, Trindade EN, Costa Filho OP et al (2020) Impact of COVID-19 outbreak on the emergency presentation of acute appendicitis. Am Surg 86(11):1508–1512PubMedPubMedCentralCrossRef Kumaira Fonseca M, Trindade EN, Costa Filho OP et al (2020) Impact of COVID-19 outbreak on the emergency presentation of acute appendicitis. Am Surg 86(11):1508–1512PubMedPubMedCentralCrossRef
30.
go back to reference Fulton J, Lazarus C (1995) Acute appendicitis among black South Africans. S Afr J Surg 33(4):165–166PubMed Fulton J, Lazarus C (1995) Acute appendicitis among black South Africans. S Afr J Surg 33(4):165–166PubMed
31.
go back to reference Gao Z, Li M, Zhou H et al (2020) Complicated appendicitis are common during the epidemic period of 2019 novel coronavirus (2019-nCoV). Asian J Surg 43(10):1002–1005PubMedPubMedCentralCrossRef Gao Z, Li M, Zhou H et al (2020) Complicated appendicitis are common during the epidemic period of 2019 novel coronavirus (2019-nCoV). Asian J Surg 43(10):1002–1005PubMedPubMedCentralCrossRef
32.
go back to reference Ghumro AA, Khaskheli NM, Memon AA et al (1996) Perforated versus non perforated appendicitis: a comparative study. JCPSP 6(4):214–216 Ghumro AA, Khaskheli NM, Memon AA et al (1996) Perforated versus non perforated appendicitis: a comparative study. JCPSP 6(4):214–216
33.
go back to reference Giiti GC, Mazigo HD, Heukelbach J et al (2010) HIV, appendectomy and postoperative complications at a reference hospital in Northwest Tanzania: cross-sectional study. AIDS Res Ther 7(47):1–6 Giiti GC, Mazigo HD, Heukelbach J et al (2010) HIV, appendectomy and postoperative complications at a reference hospital in Northwest Tanzania: cross-sectional study. AIDS Res Ther 7(47):1–6
34.
go back to reference Gürleyik G, Gürleyik E (2003) Age-related clinical features in older patients with acute appendicitis. Eur J Emerg Med 10(3):200–203PubMedCrossRef Gürleyik G, Gürleyik E (2003) Age-related clinical features in older patients with acute appendicitis. Eur J Emerg Med 10(3):200–203PubMedCrossRef
35.
go back to reference Kanumba ES, Mabula JB, Rambau P et al (2011) Modified alvarado scoring system as a diagnostic tool for acute appendicitis at Bugando Medical Centre, Mwanza, Tanzania. BMC Surg 11:1–5CrossRef Kanumba ES, Mabula JB, Rambau P et al (2011) Modified alvarado scoring system as a diagnostic tool for acute appendicitis at Bugando Medical Centre, Mwanza, Tanzania. BMC Surg 11:1–5CrossRef
36.
go back to reference Kong VY, Bulajic B, Allorto NL et al (2012) Acute appendicitis in a developing country. World J Surg 36(9):2068–2073PubMedCrossRef Kong VY, Bulajic B, Allorto NL et al (2012) Acute appendicitis in a developing country. World J Surg 36(9):2068–2073PubMedCrossRef
37.
38.
go back to reference Kong VY, Aldous C, Clarke DL (2014) Understanding the reasons for delay to definitive surgical care of patients with acute appendicitis in rural South Africa. S Afr J Surg 52(1):2–5PubMed Kong VY, Aldous C, Clarke DL (2014) Understanding the reasons for delay to definitive surgical care of patients with acute appendicitis in rural South Africa. S Afr J Surg 52(1):2–5PubMed
39.
go back to reference Kunle AE, Yinka OT, Oluyomi TA et al (2011) Surgical pathologic review of appendectomy at a sub- urban tropical tertiary hospital in Africa. JMMS 2(6):932–938 Kunle AE, Yinka OT, Oluyomi TA et al (2011) Surgical pathologic review of appendectomy at a sub- urban tropical tertiary hospital in Africa. JMMS 2(6):932–938
40.
go back to reference Lee HY, Jayalakshmi P, Syed Noori SH (1990) Acute appendicitis ~ the university hospital experience. Med J Malays 48(1):17–27 Lee HY, Jayalakshmi P, Syed Noori SH (1990) Acute appendicitis ~ the university hospital experience. Med J Malays 48(1):17–27
41.
go back to reference Levy RD, Degiannis E, Kantarovsky A et al (1997) Audit of acute appendicitis in a black South African population. S Afr J Surg 35(4):198–202PubMed Levy RD, Degiannis E, Kantarovsky A et al (1997) Audit of acute appendicitis in a black South African population. S Afr J Surg 35(4):198–202PubMed
42.
go back to reference Li J, Xu R, Hu DM et al (2019) Effect of delay to operation on outcomes in patients with acute appendicitis: a systematic review and meta-analysis. J Gastrointest Surg 23(1):210–223PubMedCrossRef Li J, Xu R, Hu DM et al (2019) Effect of delay to operation on outcomes in patients with acute appendicitis: a systematic review and meta-analysis. J Gastrointest Surg 23(1):210–223PubMedCrossRef
43.
go back to reference Moustakis J, Piperidis AA, Ogunrombi AB (2020) The effect of COVID-19 on essential surgical admissions in South Africa: a retrospective observational analysis of admissions before and during lockdown at a tertiary healthcare complex. S Afr Med J 110(9):910–915PubMedCrossRef Moustakis J, Piperidis AA, Ogunrombi AB (2020) The effect of COVID-19 on essential surgical admissions in South Africa: a retrospective observational analysis of admissions before and during lockdown at a tertiary healthcare complex. S Afr Med J 110(9):910–915PubMedCrossRef
44.
go back to reference Ngim CF, Quek KF, Dhanoa A et al (2014) Pediatric appendicitis in a developing country: What are the clinical predictors and outcome of perforation? J Trop Pediatr 60(6):409–414PubMedCrossRef Ngim CF, Quek KF, Dhanoa A et al (2014) Pediatric appendicitis in a developing country: What are the clinical predictors and outcome of perforation? J Trop Pediatr 60(6):409–414PubMedCrossRef
45.
go back to reference Nshuti R, Kruger D, Luvhengo TE (2014) Clinical presentation of acute appendicitis in adults at the Chris Hani Baragwanath academic hospital. Int J Emerg Med 7(1):1–6CrossRef Nshuti R, Kruger D, Luvhengo TE (2014) Clinical presentation of acute appendicitis in adults at the Chris Hani Baragwanath academic hospital. Int J Emerg Med 7(1):1–6CrossRef
46.
go back to reference Ohene-Yeboah M, Togbe B (2006) An audit of appendicitis and appendicectomy in Kumasi. Ghana West Afr J Med 25(2):138–143PubMed Ohene-Yeboah M, Togbe B (2006) An audit of appendicitis and appendicectomy in Kumasi. Ghana West Afr J Med 25(2):138–143PubMed
47.
go back to reference Paydar S, Javidi Parsijani P, Akbarzadeh A et al (2013) Short-term outcome of open appendectomy in Southern Iran: a single center experience. Bull Emerg Trauma 1(3):123–126PubMedPubMedCentral Paydar S, Javidi Parsijani P, Akbarzadeh A et al (2013) Short-term outcome of open appendectomy in Southern Iran: a single center experience. Bull Emerg Trauma 1(3):123–126PubMedPubMedCentral
48.
go back to reference Shambe I, Dikkol N, Ozoilo K (2016) Pregnancy outcome following non-obstetric abdominal surgery in Jos University Teaching Hospital: a 5-year retrospective study. Niger J Clin Pract 19(5):591–594PubMedCrossRef Shambe I, Dikkol N, Ozoilo K (2016) Pregnancy outcome following non-obstetric abdominal surgery in Jos University Teaching Hospital: a 5-year retrospective study. Niger J Clin Pract 19(5):591–594PubMedCrossRef
49.
go back to reference Singh M, Kadian Y, Rattan K et al (2014) Complicated appendicitis: Analysis of risk factors in children. Afr J Paediatr Surg 11(2):109–113PubMedCrossRef Singh M, Kadian Y, Rattan K et al (2014) Complicated appendicitis: Analysis of risk factors in children. Afr J Paediatr Surg 11(2):109–113PubMedCrossRef
50.
go back to reference Steinman M, Rogeri PS, Lenci LL et al (2013) Appendicitis: What does really make the difference between private and public hospitals? BMC Emerg Med 13(15):1–5 Steinman M, Rogeri PS, Lenci LL et al (2013) Appendicitis: What does really make the difference between private and public hospitals? BMC Emerg Med 13(15):1–5
51.
go back to reference Williams BM, Purcell LN, Varela C et al (2021) Appendicitis mortality in a resource-limited setting: issues of access and failure to rescue. J Surg Res 259:320–325PubMedCrossRef Williams BM, Purcell LN, Varela C et al (2021) Appendicitis mortality in a resource-limited setting: issues of access and failure to rescue. J Surg Res 259:320–325PubMedCrossRef
52.
go back to reference Doumi EAMM (2009) Acute Abdomen at El Obeid hospital, Western Sudan. SJMS 4(2) Doumi EAMM (2009) Acute Abdomen at El Obeid hospital, Western Sudan. SJMS 4(2)
53.
go back to reference Seqsaqa M, Rozeik AE, Khalifa M, et al (2021) Geographic influence on postoperative complications in children with complicated appendicitis: a single center study. Ann of Pediatric Surg 17(1) Seqsaqa M, Rozeik AE, Khalifa M, et al (2021) Geographic influence on postoperative complications in children with complicated appendicitis: a single center study. Ann of Pediatric Surg 17(1)
54.
go back to reference Langenscheidt P, Lang C, Püschel W et al (1999) High rates of appendicectomy in a developing country: an attempt to contribute to a more rational use of surgical resources. Eur J Surg 165(3):248–252PubMedCrossRef Langenscheidt P, Lang C, Püschel W et al (1999) High rates of appendicectomy in a developing country: an attempt to contribute to a more rational use of surgical resources. Eur J Surg 165(3):248–252PubMedCrossRef
55.
go back to reference Maroju NK, Smile SR, Sistla SC et al (2004) Delay in surgery for acute appendicitis. ANZ J Surg 74(9):773–776PubMedCrossRef Maroju NK, Smile SR, Sistla SC et al (2004) Delay in surgery for acute appendicitis. ANZ J Surg 74(9):773–776PubMedCrossRef
57.
go back to reference Ahmed A, Dauda M, Garba S et al (2010) Emergency abdominal surgery in Zaria. Nigeria S Afr J Surg 48(2):59–62 Ahmed A, Dauda M, Garba S et al (2010) Emergency abdominal surgery in Zaria. Nigeria S Afr J Surg 48(2):59–62
58.
go back to reference Fahim F, Shirjeel S (2005) A comparison between presentation time and delay in surgery in simple and advanced appendicitis. J Ayub Med Coll Abbottabad 17(2):37–39PubMed Fahim F, Shirjeel S (2005) A comparison between presentation time and delay in surgery in simple and advanced appendicitis. J Ayub Med Coll Abbottabad 17(2):37–39PubMed
59.
go back to reference Kong VY, van de Linde S, Aldous C et al (2013) Quantifying the disparity in outcome between urban and rural patients with acute appendicitis in South Africa. S Afr Med J 103(10):742–745PubMedCrossRef Kong VY, van de Linde S, Aldous C et al (2013) Quantifying the disparity in outcome between urban and rural patients with acute appendicitis in South Africa. S Afr Med J 103(10):742–745PubMedCrossRef
60.
go back to reference Mohammed IF, AlBayati BA (2020) Acute appendicitis in pregnancy: the presentation and the outcome. Eur J Mol Clin Med 7(6):450–455 Mohammed IF, AlBayati BA (2020) Acute appendicitis in pregnancy: the presentation and the outcome. Eur J Mol Clin Med 7(6):450–455
61.
go back to reference Hernandez MC, Finnesgaard E, Aho JM et al (2018) Appendicitis: rural patient status is associated with increased duration of prehospital symptoms and worse outcomes in high- and low-middle-income countries. World J Surg 42(6):1573–1580PubMedCrossRef Hernandez MC, Finnesgaard E, Aho JM et al (2018) Appendicitis: rural patient status is associated with increased duration of prehospital symptoms and worse outcomes in high- and low-middle-income countries. World J Surg 42(6):1573–1580PubMedCrossRef
62.
go back to reference Hernandez MC, Kong VY, Bruce JL et al (2018) Pediatric appendicitis severity in KwaZulu-Natal, South Africa: a retrospective cohort analysis. World J Surg 42(11):3785–3791PubMedCrossRef Hernandez MC, Kong VY, Bruce JL et al (2018) Pediatric appendicitis severity in KwaZulu-Natal, South Africa: a retrospective cohort analysis. World J Surg 42(11):3785–3791PubMedCrossRef
63.
go back to reference Sobnach S, Ede C, Van Der Linde G et al (2019) A study comparing outcomes of appendectomy between HIV-infected and HIV-negative patients. Chirurgia (Bucur) 114(4):467–474PubMedCrossRef Sobnach S, Ede C, Van Der Linde G et al (2019) A study comparing outcomes of appendectomy between HIV-infected and HIV-negative patients. Chirurgia (Bucur) 114(4):467–474PubMedCrossRef
64.
go back to reference Ademola TO, Oludayo SA, Samuel OA et al (2015) Clinicopathological review of 156 appendicectomies for acute appendicitis in children in Ile-Ife, Nigeria: a retrospective analysis. BMC Emerg Med 15:7PubMedPubMedCentralCrossRef Ademola TO, Oludayo SA, Samuel OA et al (2015) Clinicopathological review of 156 appendicectomies for acute appendicitis in children in Ile-Ife, Nigeria: a retrospective analysis. BMC Emerg Med 15:7PubMedPubMedCentralCrossRef
65.
go back to reference Bhandari TR, Shahi S, Acharya S (2017) Acute appendicitis in pregnancy and the developing world. Int Sch Res Notices 2017:1–5CrossRef Bhandari TR, Shahi S, Acharya S (2017) Acute appendicitis in pregnancy and the developing world. Int Sch Res Notices 2017:1–5CrossRef
66.
go back to reference Calis H (2018) Morbidity and mortality in appendicitis in the elderly. J Coll Physicians Surg Pak 28(11):875–878PubMedCrossRef Calis H (2018) Morbidity and mortality in appendicitis in the elderly. J Coll Physicians Surg Pak 28(11):875–878PubMedCrossRef
67.
go back to reference Edino ST, Mohammed AZ, Ochicha O et al (2004) Appendicitis in Kano, Nigeria: A 5-year review of pattern, morbidity and mortality. Ann Afr Med 3(1):38–41 Edino ST, Mohammed AZ, Ochicha O et al (2004) Appendicitis in Kano, Nigeria: A 5-year review of pattern, morbidity and mortality. Ann Afr Med 3(1):38–41
68.
go back to reference Gupta A, Regmi S, Hazra NK et al (2010) Clinically monitored delay-a valid option in cases with doubtful diagnosis of acute appendicitis. Indian J Surg 72(3):215–219PubMedPubMedCentralCrossRef Gupta A, Regmi S, Hazra NK et al (2010) Clinically monitored delay-a valid option in cases with doubtful diagnosis of acute appendicitis. Indian J Surg 72(3):215–219PubMedPubMedCentralCrossRef
69.
go back to reference Ibis C, Albayrak D, Hatipoglu AR et al (2010) The amount of comorbidities as a single parameter has no effect in predicting the outcome in appendicitis patients older than 60 years. South Med J 103(3):202–206PubMedCrossRef Ibis C, Albayrak D, Hatipoglu AR et al (2010) The amount of comorbidities as a single parameter has no effect in predicting the outcome in appendicitis patients older than 60 years. South Med J 103(3):202–206PubMedCrossRef
70.
go back to reference Njoku TA, Okobia MN (2006) Perforated appendicitis: Risk factors and outcomes of management. Niger J Surg Sci 16(2):76–79 Njoku TA, Okobia MN (2006) Perforated appendicitis: Risk factors and outcomes of management. Niger J Surg Sci 16(2):76–79
71.
go back to reference Osifo OD, Ogiemwonyi SO (2009) Appendicitis in children: an increasing health scourge in a developing country. Pak J Med Sci 25(3):490–495 Osifo OD, Ogiemwonyi SO (2009) Appendicitis in children: an increasing health scourge in a developing country. Pak J Med Sci 25(3):490–495
72.
go back to reference Osuigwe AN, Ekwunife CN, Anyanwu SNC (2004) Childhood acute appendicitis In Nnewi Nigeria. Niger J Clin Pract 7(1):11–14 Osuigwe AN, Ekwunife CN, Anyanwu SNC (2004) Childhood acute appendicitis In Nnewi Nigeria. Niger J Clin Pract 7(1):11–14
73.
go back to reference Ozguner IF, Buyukyavuz BI, Savas MC (2004) The influence of delay on perforation in childhood appendicitis. A retrospective analysis of 58 cases. Saudi Med J 25(9):1232–1236PubMed Ozguner IF, Buyukyavuz BI, Savas MC (2004) The influence of delay on perforation in childhood appendicitis. A retrospective analysis of 58 cases. Saudi Med J 25(9):1232–1236PubMed
74.
go back to reference Pokharel N, Sapkota P, Kc B et al (2011) Acute appendicitis in elderly patients: a challenge for surgeons. Nepal Med Coll J 13(4):285–288PubMed Pokharel N, Sapkota P, Kc B et al (2011) Acute appendicitis in elderly patients: a challenge for surgeons. Nepal Med Coll J 13(4):285–288PubMed
75.
go back to reference Rahman GA, Debrah SA (2017) Complicated appendicitis: experience from central region of Ghana. Int Surg J 5(1):277–277CrossRef Rahman GA, Debrah SA (2017) Complicated appendicitis: experience from central region of Ghana. Int Surg J 5(1):277–277CrossRef
76.
go back to reference Rana MUI, Amna A, Fawad M (2018) Prevalance of appendicitis in children in a developing countries: a research study on painful and swollen appendix is increasing in the countries. Indo Am J Pharm Sci 5(10):10256–10261 Rana MUI, Amna A, Fawad M (2018) Prevalance of appendicitis in children in a developing countries: a research study on painful and swollen appendix is increasing in the countries. Indo Am J Pharm Sci 5(10):10256–10261
77.
go back to reference Reiter AJ, Schlottmann F, Kajombo C et al (2019) Surgical outcomes of acute appendicitis in high-middle- and low-income countries. Am Surg 85(2):E97–E99PubMedCrossRef Reiter AJ, Schlottmann F, Kajombo C et al (2019) Surgical outcomes of acute appendicitis in high-middle- and low-income countries. Am Surg 85(2):E97–E99PubMedCrossRef
78.
go back to reference Rogers AD, Hampton MI, Bunting M et al (2008) Audit of appendicectomies at Frere Hospital. Eastern Cape S Afr J Surg 46(3):74–77 Rogers AD, Hampton MI, Bunting M et al (2008) Audit of appendicectomies at Frere Hospital. Eastern Cape S Afr J Surg 46(3):74–77
79.
go back to reference Sulu B, Günerhan Y, Palanci Y et al (2010) Epidemiological and demographic features of appendicitis and influences of several environmental factors. Ulus Travma Acil Cerrahi Derg 16(1):38–42PubMed Sulu B, Günerhan Y, Palanci Y et al (2010) Epidemiological and demographic features of appendicitis and influences of several environmental factors. Ulus Travma Acil Cerrahi Derg 16(1):38–42PubMed
80.
go back to reference Tan PH, Teng XX, Gan ZY et al (2020) A study on the clinical factors associated with acute appendicitis and perforated appendicitis among children in a secondary medical Centre in Malaysia. Malays J Med Sci 27(4):139–146PubMedPubMedCentral Tan PH, Teng XX, Gan ZY et al (2020) A study on the clinical factors associated with acute appendicitis and perforated appendicitis among children in a secondary medical Centre in Malaysia. Malays J Med Sci 27(4):139–146PubMedPubMedCentral
81.
go back to reference Turanli S, Kiziltan G (2021) Did the COVID-19 pandemic cause a delay in the diagnosis of acute appendicitis? World J Surg 45(1):18–22PubMedCrossRef Turanli S, Kiziltan G (2021) Did the COVID-19 pandemic cause a delay in the diagnosis of acute appendicitis? World J Surg 45(1):18–22PubMedCrossRef
82.
go back to reference Willmore WS, Hill AG (2001) Acute appendicitis in a Kenyan rural hospital. East Afr Med J 78(7):355–357PubMedCrossRef Willmore WS, Hill AG (2001) Acute appendicitis in a Kenyan rural hospital. East Afr Med J 78(7):355–357PubMedCrossRef
83.
go back to reference Zhou Y, Cen LS (2020) Managing acute appendicitis during the COVID-19 pandemic in Jiaxing. China World J Clin Cases 8(19):4349–4359PubMedCrossRef Zhou Y, Cen LS (2020) Managing acute appendicitis during the COVID-19 pandemic in Jiaxing. China World J Clin Cases 8(19):4349–4359PubMedCrossRef
84.
go back to reference Miloudi N, Brahem M, Ben Abid S et al (2012) Acute appendicitis in pregnancy: specific features of diagnosis and treatment. Journal de Chirurgie Viscerale 149(4):309–314CrossRef Miloudi N, Brahem M, Ben Abid S et al (2012) Acute appendicitis in pregnancy: specific features of diagnosis and treatment. Journal de Chirurgie Viscerale 149(4):309–314CrossRef
85.
go back to reference Ghali MAE, Kaabia O, Mefteh ZB et al (2018) Acute appendicitis complicating pregnancy: a 33 case series, diagnosis and management, features, maternal and neonatal outcomes. Pan Afr Med J 30:212PubMedPubMedCentral Ghali MAE, Kaabia O, Mefteh ZB et al (2018) Acute appendicitis complicating pregnancy: a 33 case series, diagnosis and management, features, maternal and neonatal outcomes. Pan Afr Med J 30:212PubMedPubMedCentral
86.
go back to reference Terzi A, Yildiz F, Vural M et al (2010) A case series of 46 appendectomies during pregnancy. Wien Klin Wochenschr 122(23):686–690PubMedCrossRef Terzi A, Yildiz F, Vural M et al (2010) A case series of 46 appendectomies during pregnancy. Wien Klin Wochenschr 122(23):686–690PubMedCrossRef
87.
go back to reference De U, Ghosh S (2002) Acute appendicectomy for appendicular mass: a study of 87 patients. Ceylon Med J 47(4):117–118PubMedCrossRef De U, Ghosh S (2002) Acute appendicectomy for appendicular mass: a study of 87 patients. Ceylon Med J 47(4):117–118PubMedCrossRef
88.
go back to reference Ahmad N, Ali AA (2020) Acute appendicitis is still a morbid disease in the developing world. Pak J Med Health Sci 14(3):537–539 Ahmad N, Ali AA (2020) Acute appendicitis is still a morbid disease in the developing world. Pak J Med Health Sci 14(3):537–539
89.
go back to reference Sayyahfar S, Nasiri J, Dehghan KT et al (2019) Pitfalls in the diagnosis of acute appendicitis in tehran children’s hospital. Arch Pediatr Infect Dis 7(3):3–7CrossRef Sayyahfar S, Nasiri J, Dehghan KT et al (2019) Pitfalls in the diagnosis of acute appendicitis in tehran children’s hospital. Arch Pediatr Infect Dis 7(3):3–7CrossRef
90.
go back to reference Magaam S (2011) Acute appendicitis in patients with different ages at Hodeidah City. Yemen World J Med Sci 6(3):136–141 Magaam S (2011) Acute appendicitis in patients with different ages at Hodeidah City. Yemen World J Med Sci 6(3):136–141
91.
go back to reference Hernandez MC, Kong VY, Aho JM et al (2017) Increased anatomic severity in appendicitis is associated with outcomes in a South African population. J Trauma Acute Care Surg 83(1):175–181PubMedPubMedCentralCrossRef Hernandez MC, Kong VY, Aho JM et al (2017) Increased anatomic severity in appendicitis is associated with outcomes in a South African population. J Trauma Acute Care Surg 83(1):175–181PubMedPubMedCentralCrossRef
92.
go back to reference Khan MS, Siddiqui MTH, Shahzad N et al (2019) Factors associated with complicated appendicitis: view from a low-middle income country. Cureus 11:1–7 Khan MS, Siddiqui MTH, Shahzad N et al (2019) Factors associated with complicated appendicitis: view from a low-middle income country. Cureus 11:1–7
93.
go back to reference Rahman MAM, Chowdhury TK, Chowdhury MZ et al (2020) Early appendectomy for appendicular mass: operative findings and outcome in 220 children - a developing country perspective. Ann Pediatric Surg 16(39):1–5 Rahman MAM, Chowdhury TK, Chowdhury MZ et al (2020) Early appendectomy for appendicular mass: operative findings and outcome in 220 children - a developing country perspective. Ann Pediatric Surg 16(39):1–5
94.
go back to reference Singh N (2009) A new global malaria eradication strategy: implications for malaria research from an Indian perspective. Trans R Soc Trop Med Hyg 103(12):1202–1203PubMedCrossRef Singh N (2009) A new global malaria eradication strategy: implications for malaria research from an Indian perspective. Trans R Soc Trop Med Hyg 103(12):1202–1203PubMedCrossRef
95.
go back to reference Renjith V, Yesodharan R, Noronha JA, et al (2021) Qualitative methods in health care research. Int J Prev Med 12(20) Renjith V, Yesodharan R, Noronha JA, et al (2021) Qualitative methods in health care research. Int J Prev Med 12(20)
96.
go back to reference Lee SL, Shekherdimian S, Chiu VY (2011) Effect of race and socioeconomic status in the treatment of appendicitis in patients with equal health care access. Arch Surg 146(2):156–161PubMedCrossRef Lee SL, Shekherdimian S, Chiu VY (2011) Effect of race and socioeconomic status in the treatment of appendicitis in patients with equal health care access. Arch Surg 146(2):156–161PubMedCrossRef
97.
go back to reference Zafar SN, Fatmi Z, Iqbal A et al (2013) Disparities in access to surgical care within a lower income country: an alarming inequity. World J Surg 37(7):1470–1477PubMedCrossRef Zafar SN, Fatmi Z, Iqbal A et al (2013) Disparities in access to surgical care within a lower income country: an alarming inequity. World J Surg 37(7):1470–1477PubMedCrossRef
98.
go back to reference Paquette IM, Zuckerman R, Finlayson SRG (2011) Perforated appendicitis among rural and urban patients: Implications of access to care. Ann Surg 253(3):534–538PubMedCrossRef Paquette IM, Zuckerman R, Finlayson SRG (2011) Perforated appendicitis among rural and urban patients: Implications of access to care. Ann Surg 253(3):534–538PubMedCrossRef
99.
go back to reference Lassi ZS, Middleton P, Bhutta ZA, et al (2019) Health care seeking for maternal and newborn illnesses in low- and middle-income countries: a systematic review of observational and qualitative studies. F1000Res 8:200 Lassi ZS, Middleton P, Bhutta ZA, et al (2019) Health care seeking for maternal and newborn illnesses in low- and middle-income countries: a systematic review of observational and qualitative studies. F1000Res 8:200
100.
go back to reference Kempthorne P, Morriss WW, Mellin-Olsen J et al (2017) The WFSA global anesthesia workforce survey. Anesth Analg 125(3):981–990PubMedCrossRef Kempthorne P, Morriss WW, Mellin-Olsen J et al (2017) The WFSA global anesthesia workforce survey. Anesth Analg 125(3):981–990PubMedCrossRef
101.
go back to reference O’Flynn E, Andrew J, Hutch A et al (2016) The specialist surgeon workforce in East, Central and Southern Africa: a situation analysis. World J Surg 40(11):2620–2627PubMedCrossRef O’Flynn E, Andrew J, Hutch A et al (2016) The specialist surgeon workforce in East, Central and Southern Africa: a situation analysis. World J Surg 40(11):2620–2627PubMedCrossRef
102.
go back to reference Siddiqi S, Kielmann AA, Khan MS et al (2001) The effectiveness of patient referral in Pakistan. Health Policy Plan 16(2):193–198PubMedCrossRef Siddiqi S, Kielmann AA, Khan MS et al (2001) The effectiveness of patient referral in Pakistan. Health Policy Plan 16(2):193–198PubMedCrossRef
103.
go back to reference Odland ML, Whitaker J, Nepogodiev D et al (2020) Identifying, prioritizing and visually mapping barriers to Injury Care in Rwanda: a multi-disciplinary stakeholder exercise. World J Surg 44(9):2903–2918PubMedPubMedCentralCrossRef Odland ML, Whitaker J, Nepogodiev D et al (2020) Identifying, prioritizing and visually mapping barriers to Injury Care in Rwanda: a multi-disciplinary stakeholder exercise. World J Surg 44(9):2903–2918PubMedPubMedCentralCrossRef
104.
go back to reference Swart O, Esterhuizen TM, Voss M (2021) The role of treatment delays in surgical site infection after appendicectomy in a South African rural regional hospital. S Afr Med J 111(3):271–275PubMedCrossRef Swart O, Esterhuizen TM, Voss M (2021) The role of treatment delays in surgical site infection after appendicectomy in a South African rural regional hospital. S Afr Med J 111(3):271–275PubMedCrossRef
Metadata
Title
Factors Contributing to Delays to Accessing Appendectomy in Low- and Middle-Income Countries: A Scoping Review
Authors
Johnelize Louw
M. McCaul
R. English
P. S. Nyasulu
J. Davies
C. Fourie
J. Jassat
K. M. Chu
Publication date
25-09-2023
Publisher
Springer International Publishing
Published in
World Journal of Surgery / Issue 12/2023
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-023-07183-2

Other articles of this Issue 12/2023

World Journal of Surgery 12/2023 Go to the issue