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World Journal of Surgery

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01-09-2019 | Opioids | Scientific Review

Chronic Postoperative Opioid Use: A Systematic Review

Authors: Ashley Hinther, Omar Abdel-Rahman, Winson Y. Cheung, May Lynn Quan, Joseph C. Dort

Published in: World Journal of Surgery | Issue 9/2019

Abstract

Background

There are a number of studies in the literature that describe the prevalence, causes, and factors associated with chronic postoperative opioid use, but there is a lack of synthesis of the literature to guide clinicians in optimally managing postoperative pain while avoiding opioid dependence. Thus, the goal of this study was to perform a systematic review of the literature to investigate the prevalence of chronic postoperative opioid use and the associated risk factors.

Materials and methods

A systematic search was performed using Ovid Medline and Embase according to PRISMA guidelines. Data were collected on the following outcomes of interest: prevalence of opioid use at 3, 6, and 12 months postoperatively, and risk factors associated with chronic postoperative opioid use.

Results

Forty-three articles were included in the final analysis. The mean prevalence of chronic postoperative opioid use in all populations at 3, 6, and 12 months postoperatively was 30.5%, 25.6%, and 25.2%, respectively. The prevalence of patients who developed chronic opioid use at 3, 6, and 12 months postoperatively was 10.4%, 8.5%, and 9.8%, respectively. Forty of the articles analyzed risk factors associated with chronic postoperative opioid use. The most common associated risk factor identified was preoperative opioid use with 27 articles demonstrating a significant association with chronic postoperative opioid use.

Discussion

The current opioid crisis is in part secondary to the prevalence of chronic opioid use following surgery. This study identified associated risk factors with chronic postoperative opioid use, which may help identify patients at risk for developing chronic postoperative opioid use.

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Title: Chronic Postoperative Opioid Use: A Systematic Review
Authors: Ashley Hinther
Omar Abdel-Rahman
Winson Y. Cheung
May Lynn Quan
Joseph C. Dort
Publication date: 01-09-2019
Publisher: Springer International Publishing
Keywords: Opioids
Opioids
Published in: World Journal of Surgery / Issue 9/2019
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-019-05016-9

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Chronic Postoperative Opioid Use: A Systematic Review

Abstract

Background

Materials and methods

Results

Discussion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Materials and methods

Results

Discussion

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