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01-11-2018 | Original Scientific Report

Risk Factors for Postoperative Delirium After Gastrectomy in Gastric Cancer Patients

Authors: Shinsaku Honda, Kenichiro Furukawa, Noriyuki Nishiwaki, Keiichi Fujiya, Hayato Omori, Sanae Kaji, Rie Makuuchi, Tomoyuki Irino, Yutaka Tanizawa, Etsuro Bando, Taiichi Kawamura, Masanori Terashima

Published in: World Journal of Surgery | Issue 11/2018

Abstract

Purpose

The incidence of postoperative delirium is reported to range from 9 to 87%; however, no report has focused on cases of postoperative delirium in gastric cancer surgery alone. Therefore, we investigated the incidence of and risk factors for postoperative delirium after gastrectomy in patients with gastric cancer.

Methods

A total of 1037 patients who underwent surgery were included in the study. Patients were divided into two groups—those with (delirium group) or without (non-delirium group) postoperative delirium—and their backgrounds were compared. The short-term outcomes and the overall survival were also investigated.

Results

Postoperative delirium was observed in 47 of 1037 patients (4.5%). A multivariate analysis revealed that male gender, age ≥ 75 years, a history of cerebrovascular disease, and the habitual use of sleeping pills were independent predictive factors for postoperative delirium. The postoperative hospital stay was significantly longer in the postoperative delirium group than in the non-delirium group. Postoperative delirium was significantly associated with postoperative complications. The 3-year overall survival was 74.3% in the delirium group and 85.5% in the non-delirium group (log-rank p = 0.006). A multivariate analysis revealed that postoperative delirium was an independent prognostic factor, along with the age and cancer stage.

Conclusion

The incidence of postoperative delirium was 4.5% in gastric cancer patients. Male gender, age ≥ 75 years, a history of cerebrovascular disease, and the habitual use of narcoleptic agents were risk factors for postoperative delirium after gastrectomy in gastric cancer patients. Postoperative delirium was strongly associated with other postoperative complications and a poor survival after surgery.

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Title: Risk Factors for Postoperative Delirium After Gastrectomy in Gastric Cancer Patients
Authors: Shinsaku Honda
Kenichiro Furukawa
Noriyuki Nishiwaki
Keiichi Fujiya
Hayato Omori
Sanae Kaji
Rie Makuuchi
Tomoyuki Irino
Yutaka Tanizawa
Etsuro Bando
Taiichi Kawamura
Masanori Terashima
Publication date: 01-11-2018
Publisher: Springer International Publishing
Published in: World Journal of Surgery / Issue 11/2018
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-018-4682-y

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Risk Factors for Postoperative Delirium After Gastrectomy in Gastric Cancer Patients

Abstract

Purpose

Methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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