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World Journal of Surgery
Published in: World Journal of Surgery 4/2016

01-04-2016 | Reply, Letter to the Editor

Clinical Usefulness of 5-FU Metabolic Enzymes as Predictive Markers of Response to Chemotherapy in Colorectal Cancer

Authors: Kohei Shigeta, Yoshiyuki Ishii, Hirotoshi Hasegawa, Koji Okabayashi, Yuko Kitagawa

Published in: World Journal of Surgery | Issue 4/2016

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Excerpt

To the Editor, …
Literature
1.
Shigeta K, Ishii Y, Hasegawa H et al (2014) Evaluation of 5-fluorouracil metabolic enzymes as predictors of response to adjuvant chemotherapy outcomes in patients with stage II/III colorectal cancer: a decision-curve analysis. World J Surg 38:3248–3256. doi:10.​1007/​s00268-014-2738-1 CrossRefPubMed
2.
Boni V, Bitarte N, Cristobal I et al (2010) miR-192/miR-215 influence 5-fluorouracil resistance through cell cycle-mediated mechanisms complementary to its post-transcriptional thymidilate synthase regulation. Mol Cancer Ther 9:2265–2275CrossRefPubMed
3.
Paradiso A, Simone G, Petroni S et al (2000) Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients. Br J Cancer 82:560–567PubMedCentralCrossRefPubMed
4.
Sadahiro S, Suzuki T, Tanaka A et al (2012) Association of right-sided tumors with high thymidine phosphorylase gene expression levels and the response to oral uracil and tegafur/leucovorin chemotherapy among patients with colorectal cancer. Cancer Chemother Pharmacol 70(285–29):1
5.
Carames C, Cristobal I, Moreno V et al (2015) MicroRNA-21 predicts response to preoperative chemoradiotherapy in locally advanced rectal cancer. Int J Colorectal Dis 30:899–906CrossRefPubMed
Metadata
Title
Clinical Usefulness of 5-FU Metabolic Enzymes as Predictive Markers of Response to Chemotherapy in Colorectal Cancer
Authors
Kohei Shigeta
Yoshiyuki Ishii
Hirotoshi Hasegawa
Koji Okabayashi
Yuko Kitagawa
Publication date
01-04-2016
Publisher
Springer International Publishing
Published in
World Journal of Surgery / Issue 4/2016
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-015-3286-z

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Letter to the Editor

Clinical Usefulness of 5-FU Metabolic Enzymes as Predictive Markers of Response to Chemotherapy in Colorectal Cancer