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01-09-2015 | Original Scientific Report

Quality of Life After Living Donor Hepatectomy for Liver Transplantation

Authors: Abu Bakar Hafeez Bhatti, Haseeb Zia, Faisal Saud Dar, Mariam Qasim Zia, Amara Nasir, Farah Saif, Abdul WahabYousafzai, Farah Imtiaz, Mohammad Salih, Najmul Hassan Shah

Published in: World Journal of Surgery | Issue 9/2015

Abstract

Background

Living donor liver transplantation (LDLT) involves healthy individuals undergoing voluntary major hepatic resection. LDLT program only started in 2012 in Pakistan and its impact on donor’s quality of life (QOL) post resection is not known. The objective of this study was to determine health-related QOL in donors who underwent hepatectomy in country’s first liver transplant program.

Methods

A total of 60 donors who underwent hepatectomy between 2012 and 2014 with a minimum follow-up of 6 months were included in the study. Short form (SF-36) and Profile of mood states (POMS-65) was used to assess QOL. In addition scores were compared between patients who did and did not develop complications.

Result

Mean time duration between hepatectomy and administration of questionnaire was 15 ± 5.1 months. Median age was 28 (19–45) years. Mean BMI was 24.4 ± 3.7. A total of 7 (11.6 %) Grade 3 and above complications were observed in donors. Donors exceeded a score of 90 in 6 out of 8 evaluated categories on SF-36. The highest mean score was recorded for emotional role limitation 95.5 ± 17.1 and lowest for energy 84.8 ± 17.5. The mean score for anger was 6.6 ± 7.5. Donors also did well on the POMS vigor score with a mean of 22.7 ± 5. No significant difference in scores was observed between donors with and without complications for any of the categories except tension. Donors who developed complications post-operatively had a significantly low mean tension score of 1.5 versus 3.8 for donors without complications.

Conclusion

Acceptable post donation QOL was achieved and surgical complications did not adversely affect SF-36 and POMS scores.

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Title: Quality of Life After Living Donor Hepatectomy for Liver Transplantation
Authors: Abu Bakar Hafeez Bhatti
Haseeb Zia
Faisal Saud Dar
Mariam Qasim Zia
Amara Nasir
Farah Saif
Abdul WahabYousafzai
Farah Imtiaz
Mohammad Salih
Najmul Hassan Shah
Publication date: 01-09-2015
Publisher: Springer International Publishing
Published in: World Journal of Surgery / Issue 9/2015
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-015-3086-5

At a glance: The STEP trials

Springer Medicine

Quality of Life After Living Donor Hepatectomy for Liver Transplantation

Abstract

Background

Methods

Result

Conclusion

At a glance: The STEP trials

Springer Medicine

Abstract

Background

Methods

Result

Conclusion

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