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Published in:

01-10-2013

National Survey of Fluid Therapy in Acute Pancreatitis: Current Practice Lacks a Sound Evidence Base

Authors: Matthew D. Haydock, Anubhav Mittal, Marc van den Heever, Jeremy I. Rossaak, Saxon Connor, Michael Rodgers, Maxim S. Petrov, John A. Windsor, On behalf of the Pancreas Network of New Zealand

Published in: World Journal of Surgery | Issue 10/2013

Abstract

Background

Fluid therapy (FT) is a critical intervention in managing acute pancreatitis (AP). There is a paucity of evidence to guide FT and virtually no data on current prescribing practice. This survey aims to characterize current practice and opinion with regard to FT in AP throughout New Zealand.

Methods

Information was collected on fluid selection, administration, and goal-directed FT. The survey was distributed online and in print to all doctors employed in General Surgery Departments in New Zealand on 1 May 2012. Monthly email reminders were sent for 6 months.

Results

The overall response rate was 47 % (n = 190/408). Crystalloids were the preferred initial fluid for all categories of severity; however, colloid use increased with severity (p < 0.001). Fluid volume also increased with severity (p = 0.001), with 74 % of respondents prescribing >4 L for AP with organ failure (OF). Clinicians treating 26–50 patients per year with AP were less likely to prescribe colloid for AP with OF (8 vs 43 %) (p = 0.001). Rate of fluid administration in AP with OF varied according to physicians’ seniority (p = 0.004); consultants prescribed >4 L more than other groups (83 vs 68 %). Only 17 % of respondents reported the use of guidelines.

Conclusions

This survey reveals significant variation in prescription of FT for AP, and aggressive FT is commonly prescribed for AP with OF. There is little adherence to published guidelines or best available evidence.

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Title: National Survey of Fluid Therapy in Acute Pancreatitis: Current Practice Lacks a Sound Evidence Base
Authors: Matthew D. Haydock
Anubhav Mittal
Marc van den Heever
Jeremy I. Rossaak
Saxon Connor
Michael Rodgers
Maxim S. Petrov
John A. Windsor
On behalf of the Pancreas Network of New Zealand
Publication date: 01-10-2013
Publisher: Springer US
Published in: World Journal of Surgery / Issue 10/2013
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-013-2105-7

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

National Survey of Fluid Therapy in Acute Pancreatitis: Current Practice Lacks a Sound Evidence Base

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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