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Published in: World Journal of Surgery 3/2012

01-03-2012

How to Manage Thyroid Nodules With Two Consecutive Non-Diagnostic Results on Ultrasonography-Guided Fine-Needle Aspiration

Authors: Hee Jung Moon, Jin Young Kwak, Yoon Seong Choi, Eun-Kyung Kim

Published in: World Journal of Surgery | Issue 3/2012

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Abstract

Background

The aim of this study was to investigate the factors for considering surgery on thyroid nodules that had non-diagnostic results on two consecutive cytology examinations.

Methods

A total of 104 thyroid nodules with two consecutive non-diagnostic cytology examinations in 104 patients were investigated. Nodules with one or more suspicious ultrasonography (US) features of marked hypoechogenicity, a not well defined margin, microcalcifications, or a taller-than-wide shape were assessed as sonographically suspicious. Those without any suspicious features were assessed as sonographically benign. The clinicopathologic characteristics of patients and US features of the nodules were compared according to malignancy and benignity. The odds ratio for predicting malignancy was calculated.

Results

Altogether, 12 nodules were malignant, and 92 were benign. Age, sex, nodule size, and solidness were not associated with malignancy (P = 0.73, 0.92, 0.48, and 0.73, respectively). The malignancy rate of sonographically suspicious nodules was 25.7%, higher than the 4.3% of sonographically benign nodules (P = 0.002). The odds ratio of sonographically suspicious nodules for predicting malignancy was 16.01 (95% confidence interval 2.36–108.54, P = 0.005).

Conclusions

Based on sonographic features, surgery can be performed selectively on nodules with two consecutive non-diagnostic cytology results.
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Metadata
Title
How to Manage Thyroid Nodules With Two Consecutive Non-Diagnostic Results on Ultrasonography-Guided Fine-Needle Aspiration
Authors
Hee Jung Moon
Jin Young Kwak
Yoon Seong Choi
Eun-Kyung Kim
Publication date
01-03-2012
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 3/2012
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-011-1397-8

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