Skip to main content
Top
Published in: World Journal of Surgery 5/2009

01-05-2009

Predictive Factors for Morbidity and Mortality in Patients Undergoing Laparoscopic Paraesophageal Hernia Repair: Age, ASA Score and Operation Type Influence Morbidity

Authors: Hannes J. Larusson, Urs Zingg, Dieter Hahnloser, Karen Delport, Burkhardt Seifert, Daniel Oertli

Published in: World Journal of Surgery | Issue 5/2009

Login to get access

Abstract

Background

Patients undergoing laparoscopic paraesophageal hernia (PEH) repair risk substantial morbidity. The aim of the present study was to analyze predictive factors for postoperative morbidity and mortality.

Methods

A total of 354 laparoscopic PEH repairs were analyzed from the database of the Swiss Association for Laparoscopic and Thoracoscopic Surgery (SALTS). Age (<70 and ≥70 years) and risk (low: American Society of Anesthesiologists (ASA) scores 1 + 2; high ASA scores 3 + 4) groups were defined and multivariate logistic regression was conducted.

Results

In patients ≥70 years of age postoperative morbidity (24.4% versus 10.1%; p = 0.001) and mortality (2.4% versus 0%; p = 0.045) were significantly higher than in patients <70 years of age. In patients with gastropexy, this significant age difference was again present (38.8% versus 10.5%; p = 0.001) whereas in patients with fundoplication no difference between age groups occurred (11.9% versus 10.1%; p = 0.65). Mortality did not differ. High-risk patients had a significantly higher morbidity (26.0% versus 11.2%; p = 0.001) but not mortality (2.1% versus 0.4%; p = 0.18). The multivariate logistic regression identified the following variables as influencing postoperative morbidity: Age ≥70 years (Odds Ratio [OR] 1.99 [95% CI 1.06 to 3.74], p = 0.033); ASA 3 + 4 (OR 2.29 [95% Confidence Interval (CI) 1.22 to 4.3]; p = 0.010); type of operation (gastropexy) (OR 2.36 [95% CI 1.27 to 4.37]; p = 0.006).

Conclusions

In patients undergoing laparoscopic paraesophageal hernia repair age, ASA score, and type of operation significantly influence postoperative morbidity and mortality. Morbidity is substantial among elderly patients and those with co-morbidity, questioning the paradigm for surgery in all patients. The indication for surgery must be carefully balanced against the individual patient’s co-morbidities, age, and symptoms, and the potentially life threatening complications.
Literature
1.
go back to reference Gantert WA, Patti MG, Arcerito M et al (1998) Laparoscopic repair of paraesophageal hiatal hernias. J Am Coll Surg 186:428–432 discussion 432–423PubMedCrossRef Gantert WA, Patti MG, Arcerito M et al (1998) Laparoscopic repair of paraesophageal hiatal hernias. J Am Coll Surg 186:428–432 discussion 432–423PubMedCrossRef
2.
go back to reference Ferri LE, Feldman LS, Stanbridge D et al (2005) Should laparoscopic paraesophageal hernia repair be abandoned in favour of the open approach? Surg Endosc 19:4–8PubMedCrossRef Ferri LE, Feldman LS, Stanbridge D et al (2005) Should laparoscopic paraesophageal hernia repair be abandoned in favour of the open approach? Surg Endosc 19:4–8PubMedCrossRef
3.
go back to reference Draaisma WA, Gooszen HG, Tournoij E et al (2005) Controversies in paraesophageal hernia repair: a review of literature. Surg Endosc 19:1300–1308PubMedCrossRef Draaisma WA, Gooszen HG, Tournoij E et al (2005) Controversies in paraesophageal hernia repair: a review of literature. Surg Endosc 19:1300–1308PubMedCrossRef
4.
go back to reference Mehta S, Boddy A, Rhodes M (2006) Review of outcome after laparoscopic paraesophageal hiatal hernia repair. Surg Laparosc Endosc Percutan Tech 16:301–306PubMedCrossRef Mehta S, Boddy A, Rhodes M (2006) Review of outcome after laparoscopic paraesophageal hiatal hernia repair. Surg Laparosc Endosc Percutan Tech 16:301–306PubMedCrossRef
5.
go back to reference Skinner DB, Belsey RH (1967) Surgical management of esophageal reflux and hiatus hernia. Long-term results with 1,030 patients. J Thorac Cardiovasc Surg 53:33–54PubMed Skinner DB, Belsey RH (1967) Surgical management of esophageal reflux and hiatus hernia. Long-term results with 1,030 patients. J Thorac Cardiovasc Surg 53:33–54PubMed
6.
go back to reference Stylopoulos N, Gazelle GS, Rattner DW (2002) Paraesophageal hernias: operation or observation? Ann Surg 236:492–500; discussion 500–501PubMedCrossRef Stylopoulos N, Gazelle GS, Rattner DW (2002) Paraesophageal hernias: operation or observation? Ann Surg 236:492–500; discussion 500–501PubMedCrossRef
7.
go back to reference Parameswaran R, Ali A, Velmurugan S et al (2006) Laparoscopic repair of large paraesophageal hiatus hernia: quality of life and durability. Surg Endosc 20:1221–1224PubMedCrossRef Parameswaran R, Ali A, Velmurugan S et al (2006) Laparoscopic repair of large paraesophageal hiatus hernia: quality of life and durability. Surg Endosc 20:1221–1224PubMedCrossRef
8.
go back to reference Targarona EM, Novell J, Vela S et al (2004) Mid term analysis of safety and quality of life after the laparoscopic repair of paraesophageal hiatal hernia. Surg Endosc 18:1045–1050PubMedCrossRef Targarona EM, Novell J, Vela S et al (2004) Mid term analysis of safety and quality of life after the laparoscopic repair of paraesophageal hiatal hernia. Surg Endosc 18:1045–1050PubMedCrossRef
9.
go back to reference Zaninotto G, Portale G, Costantini M et al (2007) Objective follow-up after laparoscopic repair of large type III hiatal hernia. Assessment of safety and durability. World J Surg 31:2177–2183PubMedCrossRef Zaninotto G, Portale G, Costantini M et al (2007) Objective follow-up after laparoscopic repair of large type III hiatal hernia. Assessment of safety and durability. World J Surg 31:2177–2183PubMedCrossRef
10.
go back to reference Pierre AF, Luketich JD, Fernando HC et al (2002) Results of laparoscopic repair of giant paraesophageal hernias: 200 consecutive patients. Ann Thorac Surg 74:1909–1915; discussion 1915–1906PubMedCrossRef Pierre AF, Luketich JD, Fernando HC et al (2002) Results of laparoscopic repair of giant paraesophageal hernias: 200 consecutive patients. Ann Thorac Surg 74:1909–1915; discussion 1915–1906PubMedCrossRef
11.
go back to reference Mattar SG, Bowers SP, Galloway KD et al (2002) Long-term outcome of laparoscopic repair of paraesophageal hernia. Surg Endosc 16:745–749PubMedCrossRef Mattar SG, Bowers SP, Galloway KD et al (2002) Long-term outcome of laparoscopic repair of paraesophageal hernia. Surg Endosc 16:745–749PubMedCrossRef
12.
go back to reference Wu JS, Dunnegan DL, Soper NJ (1999) Clinical and radiologic assessment of laparoscopic paraesophageal hernia repair. Surg Endosc 13:497–502PubMedCrossRef Wu JS, Dunnegan DL, Soper NJ (1999) Clinical and radiologic assessment of laparoscopic paraesophageal hernia repair. Surg Endosc 13:497–502PubMedCrossRef
13.
go back to reference Hashemi M, Peters JH, DeMeester TR et al (2000) Laparoscopic repair of large type III hiatal hernia: objective followup reveals high recurrence rate. J Am Coll Surg 190:553–560 discussion 560–551PubMedCrossRef Hashemi M, Peters JH, DeMeester TR et al (2000) Laparoscopic repair of large type III hiatal hernia: objective followup reveals high recurrence rate. J Am Coll Surg 190:553–560 discussion 560–551PubMedCrossRef
14.
go back to reference Gangopadhyay N, Perrone JM, Soper NJ et al (2006) Outcomes of laparoscopic pa24raesophageal hernia repair in elderly and high-risk patients. Surgery 140:491–498 discussion 498–499PubMedCrossRef Gangopadhyay N, Perrone JM, Soper NJ et al (2006) Outcomes of laparoscopic pa24raesophageal hernia repair in elderly and high-risk patients. Surgery 140:491–498 discussion 498–499PubMedCrossRef
15.
go back to reference Edye MB, Canin-Endres J, Gattorno F et al (1998) Durability of laparoscopic repair of paraesophageal hernia. Ann Surg 228:528–535PubMedCrossRef Edye MB, Canin-Endres J, Gattorno F et al (1998) Durability of laparoscopic repair of paraesophageal hernia. Ann Surg 228:528–535PubMedCrossRef
16.
go back to reference Casabella F, Sinanan M, Horgan S et al (1996) Systematic use of gastric fundoplication in laparoscopic repair of paraesophageal hernias. Am J Surg 171:485–489PubMedCrossRef Casabella F, Sinanan M, Horgan S et al (1996) Systematic use of gastric fundoplication in laparoscopic repair of paraesophageal hernias. Am J Surg 171:485–489PubMedCrossRef
17.
go back to reference Lal DR, Pellegrini CA, Oelschlager BK (2005) Laparoscopic repair of paraesophageal hernia. Surg Clin North Am 85:105–118PubMedCrossRef Lal DR, Pellegrini CA, Oelschlager BK (2005) Laparoscopic repair of paraesophageal hernia. Surg Clin North Am 85:105–118PubMedCrossRef
18.
go back to reference Leeder PC, Smith G, Dehn TC (2003) Laparoscopic management of large paraesophageal hiatal hernia. Surg Endosc 17:1372–1375PubMedCrossRef Leeder PC, Smith G, Dehn TC (2003) Laparoscopic management of large paraesophageal hiatal hernia. Surg Endosc 17:1372–1375PubMedCrossRef
19.
go back to reference Dahlberg PS, Deschamps C, Miller DL et al (2001) Laparoscopic repair of large paraesophageal hiatal hernia. Ann Thorac Surg 72:1125–1129PubMedCrossRef Dahlberg PS, Deschamps C, Miller DL et al (2001) Laparoscopic repair of large paraesophageal hiatal hernia. Ann Thorac Surg 72:1125–1129PubMedCrossRef
20.
go back to reference Oelschlager BK, Pellegrini CA, Hunter J et al (2006) Biologic prosthesis reduces recurrence after laparoscopic paraesophageal hernia repair: a multicenter, prospective, randomized trial. Ann Surg 244:481–490PubMed Oelschlager BK, Pellegrini CA, Hunter J et al (2006) Biologic prosthesis reduces recurrence after laparoscopic paraesophageal hernia repair: a multicenter, prospective, randomized trial. Ann Surg 244:481–490PubMed
22.
go back to reference Francis J, Kapoor WN (1992) Prognosis after hospital discharge of older medical patients with delirium. J Am Geriatr Soc 40:601–606PubMed Francis J, Kapoor WN (1992) Prognosis after hospital discharge of older medical patients with delirium. J Am Geriatr Soc 40:601–606PubMed
23.
go back to reference Andujar JJ, Papasavas PK, Birdas T et al (2004) Laparoscopic repair of large paraesophageal hernia is associated with a low incidence of recurrence and reoperation. Surg Endosc 18:444–447PubMedCrossRef Andujar JJ, Papasavas PK, Birdas T et al (2004) Laparoscopic repair of large paraesophageal hernia is associated with a low incidence of recurrence and reoperation. Surg Endosc 18:444–447PubMedCrossRef
24.
go back to reference Luketich JD, Raja S, Fernando HC et al (2000) Laparoscopic repair of giant paraesophageal hernia: 100 consecutive cases. Ann Surg 232:608–618PubMedCrossRef Luketich JD, Raja S, Fernando HC et al (2000) Laparoscopic repair of giant paraesophageal hernia: 100 consecutive cases. Ann Surg 232:608–618PubMedCrossRef
25.
go back to reference Allen MS, Trastek VF, Deschamps C et al (1993) Intrathoracic stomach. Presentation and results of operation. J Thorac Cardiovasc Surg 105:253–258; discussion 258–259PubMed Allen MS, Trastek VF, Deschamps C et al (1993) Intrathoracic stomach. Presentation and results of operation. J Thorac Cardiovasc Surg 105:253–258; discussion 258–259PubMed
26.
go back to reference Diaz S, Brunt LM, Klingensmith ME et al (2003) Laparoscopic paraesophageal hernia repair, a challenging operation: medium-term outcome of 116 patients. J Gastrointest Surg 7:59–66; discussion 66–57PubMedCrossRef Diaz S, Brunt LM, Klingensmith ME et al (2003) Laparoscopic paraesophageal hernia repair, a challenging operation: medium-term outcome of 116 patients. J Gastrointest Surg 7:59–66; discussion 66–57PubMedCrossRef
27.
go back to reference Velanovich V, Karmy-Jones R (2001) Surgical management of paraesophageal hernias: outcome and quality of life analysis. Dig Surg 18:432–437; discussion 437–438PubMedCrossRef Velanovich V, Karmy-Jones R (2001) Surgical management of paraesophageal hernias: outcome and quality of life analysis. Dig Surg 18:432–437; discussion 437–438PubMedCrossRef
Metadata
Title
Predictive Factors for Morbidity and Mortality in Patients Undergoing Laparoscopic Paraesophageal Hernia Repair: Age, ASA Score and Operation Type Influence Morbidity
Authors
Hannes J. Larusson
Urs Zingg
Dieter Hahnloser
Karen Delport
Burkhardt Seifert
Daniel Oertli
Publication date
01-05-2009
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 5/2009
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-009-9958-9

Other articles of this Issue 5/2009

World Journal of Surgery 5/2009 Go to the issue