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World Journal of Surgery

Published in:

01-02-2010

Central Lymph Node Metastasis: Is It a Reliable Indicator of Lateral Node Involvement in Papillary Thyroid Carcinoma?

Authors: Gui-Zhou Xiao, Li Gao

Published in: World Journal of Surgery | Issue 2/2010

Abstract

Background

The purpose of the present study was to evaluate the reliability of central lymph node metastases in predicting lateral node involvement in papillary thyroid carcinoma (PTC).

Methods

This retrospective study consists of 121 patients with PTC who underwent ipsilateral selective neck dissection. The quantitative relationship between central and lateral lymph node metastases (LNM) was analyzed.

Results

A total of 86 patients (71.1%) had pathologically proven LNM; 55 patients had LNM in both the central and lateral compartments, 22 patients had only central LNM, and 9 patients had skip metastasis to lateral nodes. The sensitivity of central node involvement to predict lateral LNM was 85.9%, the specificity was 61.4%. The presence of two or more positive central nodes was associated with a high incidence of lateral LNM (70–93.3%), when compared with none (20.5%) or one (47.4%) positive central node.

Conclusions

The node status of the central compartment is moderately predictive of that of lateral compartment. The presence of two or more positive central nodes may be of value in predicting lateral node involvement.

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Title: Central Lymph Node Metastasis: Is It a Reliable Indicator of Lateral Node Involvement in Papillary Thyroid Carcinoma?
Authors: Gui-Zhou Xiao
Li Gao
Publication date: 01-02-2010
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 2/2010
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-009-0347-1

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Central Lymph Node Metastasis: Is It a Reliable Indicator of Lateral Node Involvement in Papillary Thyroid Carcinoma?

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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