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01-10-2006

Outcomes of Surgery for Intraductal Papillary Mucinous Neoplasms of the Pancreas

Authors: Yasuhiro Fujino, MD, PhD, Yasuyuki Suzuki, MD, PhD, Takuro Yoshikawa, MD, PhD, Tetsuo Ajiki, MD, PhD, Takashi Ueda, MD, PhD, Ippei Matsumoto, MD, PhD, Yoshikazu Kuroda, MD, PhD

Published in: World Journal of Surgery | Issue 10/2006

Abstract

Background

Our objective was to evaluate outcomes of surgery for intraductal papillary mucinous neoplasms of the pancreas (IPMN) in terms of the clinicopathological features.

Methods

Fifty-seven patients with IPMN were examined using clinicopathological analyses to evaluate appropriate surgical treatment, including total pancreatectomy (TP). IPMN was classified into two types: main-duct type (MD, n = 33) and branch-duct type (BD, n = 24).

Results

Ultrasound (US) and computed tomography (CT) examinations easily revealed the main site of the lesions. Intraoperative US was the most useful device for diagnosis of lateral spreading, and accuracy rates were 74% for MD and 96% for BD. TP was performed on 16 patients and was appropriate for removing neoplastic lesions with malignancy or malignant potential in 12. Three patients who underwent partial pancreatectomy with involved cancer died of progressive disease. MD is a strong predictive factor in malignancy and indicative of TP. Concerning long-term outcomes, 5 of 16 patients suffered from severe hypoglycemia, and 2 of 16 died from this condition.

Conclusion

Partial resection with cancer clearance was applied for BD-type IPMN. TP should be performed on selected patients with MD-type IPMN.

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Title: Outcomes of Surgery for Intraductal Papillary Mucinous Neoplasms of the Pancreas
Authors: Yasuhiro Fujino, MD, PhD
Yasuyuki Suzuki, MD, PhD
Takuro Yoshikawa, MD, PhD
Tetsuo Ajiki, MD, PhD
Takashi Ueda, MD, PhD
Ippei Matsumoto, MD, PhD
Yoshikazu Kuroda, MD, PhD
Publication date: 01-10-2006
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 10/2006
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-006-0051-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Outcomes of Surgery for Intraductal Papillary Mucinous Neoplasms of the Pancreas

Abstract

Background

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusion

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