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World Journal of Surgery
Published in: World Journal of Surgery 9/2005

01-09-2005

Abdominal Angina in Patients with a Midgut Carcinoid, a Sign of Severe Pathology

Authors: Harry de Vries, M.D., Rob T. M. Wijffels, M.D., Pax H. B. Willemse, M.D., Ph.D., René C. J. Verschueren, M.D., Ph.D., Ido P. Kema, Ph.D., Arend Karrenbeld, M.D., Ted R. Prins, M.D., Elisabeth G. E. de Vries, M.D., Ph.D.

Published in: World Journal of Surgery | Issue 9/2005

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Abstract

In 36 consecutive patients with a foregut carcinoid with extensive local tumor growth and liver metastases with a carcinoid syndrome, six patients had complaints of postprandial abdominal pain and attacks of subileus based on segmental intestinal ischemia. A diagnosis of abdominal angina was supported by a positive response to nitroglycerin in two and ischemia of the ileum demonstrated by angiography in two other patients. Complaints were reduced in all patients after surgery. Histopathology of the resected small bowel specimens showed elastic vascular sclerosis in three patients and ischemic changes in three other patients, confirming the clinical diagnosis. Resection of ischemic bowel can provide relief in patients with segmental intestinal ischemia caused by carcinoid-induced vascular sclerosis.
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Metadata
Title
Abdominal Angina in Patients with a Midgut Carcinoid, a Sign of Severe Pathology
Authors
Harry de Vries, M.D.
Rob T. M. Wijffels, M.D.
Pax H. B. Willemse, M.D., Ph.D.
René C. J. Verschueren, M.D., Ph.D.
Ido P. Kema, Ph.D.
Arend Karrenbeld, M.D.
Ted R. Prins, M.D.
Elisabeth G. E. de Vries, M.D., Ph.D.
Publication date
01-09-2005
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 9/2005
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-005-7825-x

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