Skip to main content
Top
Published in: World Journal of Surgery 8/2006

01-08-2006

Biomedical Industrial Sponsorship and Its Impact on the Medical Literature

Author: Peter J. Morris, AC, FRS, FRCS

Published in: World Journal of Surgery | Issue 8/2006

Login to get access

Excerpt

The pharmaceutical industry plays a vital role in the development of new drugs. The industry is involved at two levels. The first is in the design and discovery of new drugs, which may occur in their own laboratories or in the university environment. The second is the research and development that brings a drug onto the market as a result of clinical trials; the latter take place in the clinic in both university and nonuniversity institutions and, for the most part, are sponsored by industry. …
Literature
1.
2.
go back to reference Montaner JSG, O’Shaughnessy MV, Schechter T. Industry-sponsored clinical research: a double edged sword. Lancet 2001;358:1893PubMedCrossRef Montaner JSG, O’Shaughnessy MV, Schechter T. Industry-sponsored clinical research: a double edged sword. Lancet 2001;358:1893PubMedCrossRef
6.
go back to reference Lexchin J, Bero LA, Djulbegovic B, et al. Pharmaceutical industry sponsorship and research outcome and quality: systematic review. BMJ 2003;326:1167PubMedCrossRef Lexchin J, Bero LA, Djulbegovic B, et al. Pharmaceutical industry sponsorship and research outcome and quality: systematic review. BMJ 2003;326:1167PubMedCrossRef
7.
go back to reference Bhandari M, Busse JW, Jackowski D, et al. Association between industry funding and statistically significant pro-industry findings in medical and surgical randomized trials. Can Med Assoc J 2004;170:477 Bhandari M, Busse JW, Jackowski D, et al. Association between industry funding and statistically significant pro-industry findings in medical and surgical randomized trials. Can Med Assoc J 2004;170:477
8.
go back to reference Melander H, Ahlqvist-Rastad J, Meijer B, et al. Evidence b(i)ased medicine: selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applications. BMJ 2003;326:xCrossRef Melander H, Ahlqvist-Rastad J, Meijer B, et al. Evidence b(i)ased medicine: selective reporting from studies sponsored by pharmaceutical industry: review of studies in new drug applications. BMJ 2003;326:xCrossRef
9.
go back to reference Als-Nielsen B, Chen W, Gluud C, et al. Association of funding and conclusions in randomized drug trials: a reflection of treatment effect or adverse events. JAMA 2003;290:921PubMedCrossRef Als-Nielsen B, Chen W, Gluud C, et al. Association of funding and conclusions in randomized drug trials: a reflection of treatment effect or adverse events. JAMA 2003;290:921PubMedCrossRef
10.
go back to reference Cho MK, Bero LA. The quality of drug studies published in symposium proceedings. Ann Intern Med 1996;124:485PubMed Cho MK, Bero LA. The quality of drug studies published in symposium proceedings. Ann Intern Med 1996;124:485PubMed
11.
go back to reference Bekelman JE, Li Y, Gross GP. Scope and impact of financial conflicts of interest in biomedical research. JAMA 2003;289:454PubMedCrossRef Bekelman JE, Li Y, Gross GP. Scope and impact of financial conflicts of interest in biomedical research. JAMA 2003;289:454PubMedCrossRef
12.
go back to reference Choudhry NK, Stelfox HT, Detsky AS. Relationships between authors of clinical practice guidelines and the pharmaceutical industry. JAMA 2002;287:612PubMedCrossRef Choudhry NK, Stelfox HT, Detsky AS. Relationships between authors of clinical practice guidelines and the pharmaceutical industry. JAMA 2002;287:612PubMedCrossRef
13.
go back to reference Stelfox HT, Chua G, O’Rourke K, et al. Conflict of interest in the debate over calcium-channel antagonists. N Engl J Med 1998;338:101PubMedCrossRef Stelfox HT, Chua G, O’Rourke K, et al. Conflict of interest in the debate over calcium-channel antagonists. N Engl J Med 1998;338:101PubMedCrossRef
Metadata
Title
Biomedical Industrial Sponsorship and Its Impact on the Medical Literature
Author
Peter J. Morris, AC, FRS, FRCS
Publication date
01-08-2006
Publisher
Springer-Verlag
Published in
World Journal of Surgery / Issue 8/2006
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI
https://doi.org/10.1007/s00268-005-0710-9

Other articles of this Issue 8/2006

World Journal of Surgery 8/2006 Go to the issue