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Published in:

01-01-2006

Changing Treatment Strategy for Gastrinoma in Patients with Zollinger-Ellison Syndrome

Authors: Masayuki Imamura, MD, Izumi Komoto, MD, Shuichi Ota, MD

Published in: World Journal of Surgery | Issue 1/2006

Abstract

We overviewed the recent development of curative surgery for gastrinoma that has been rapidly improved since the development of new localization techniques, especially the selective arterial secretagogue injection test (SASI test) and somatostatin receptor scintigraphy (SRS). A number of new pathological findings of gastrinomas in patients with Zollinger-Ellison syndrome have been accumulated in accordance with the increase of curative resection of gastrinomas, and these new findings also have contributed to the progress of the treatment strategy for grastrinomas.

Zollinger RM. Treatment of gastrinoma. Mout Sinai J Med 1984;51:401–403

Imamura M, Takahashi K, Adachi H, et al. Usefulness of selective arterial secretin injection test for localization of gastrinoma in Zollinger-Ellison syndrome. Ann Surg 1987;205:230–239PubMed

Rosato FE, Bonn J, Shapiro M, et al. Selective arterial stimulation of secretin in localization of gastrinomas. Surg Gynecol Obstet 1990;171:196–200PubMed

Doppman JL. Pancreatic endocrine tumors—the search goes on. N Engl J Med 1992;326:1770–1772PubMedCrossRef

Stamm B, Hacki WH, Kloppel G, et al. Gastrin-producing tumors and the Zollinger-Ellison syndrome. In Dayal Y, editor, Endocrine Pathology of the Gut and Pancreas, Boca Raton, FL, CRC Press, 1991;155–194

Thompson NW, Vinik AI, Eckhauser FE. Microgastrinoma of the duodenum a cause of failed operations for the Zollinger-Ellison syndrome. Ann Surg 1989;209:396–404PubMed

Schroeder W, Hoelscher AH, Beckurts KT, et al. Surgical therapy of gastrinoma with associated Zolinger-Ellison syndrome. Z Gastroenterol 1996;34:465–472

Thodiyil PA, El-Masry NS, Williamson RC. Achieving eugastrinaemia in Zollinger-Ellison syndrome: resection or enucleation? Dig Surg 2001;18:118–123PubMedCrossRef

Oberhelman HA Jr, Nelsen TS, Johnson AN, et al. Ulcerogenic tumors of the duodenum. Ann Surg. 1961;153:214–227PubMedCrossRef

10.

Oberhelman HA Jr. Excisional therapy for ulcerogenic tumors of the duodenum.: long term results. Arch Surg 1972;104:447–453PubMed

11.

Plockinger U, Wiedenmann. Neuroendocrine tumors of the gastro-entero-pancreatic system: the role of early diagnosis, genetic testing and preventive surgery. Dig Dis 2002;20:49–60PubMed

12.

Jensen RT. Zollinger-Ellison syndrome. In Doherty GM, Skogseid B, editors, Surgical Endocrinology, Philadelphia, Lippincott Williams & Wilkins, 2001;291–343

13.

Madeira I, Terris M, Voss M, et al. Prognostic factors in patients endocrine tumors of the duodenopancreatic area. Gut 1998;43:422–427PubMedCrossRef

14.

Imamura M, Takahashi K, Isobe Y, et al. Curative resection of multiple gastrinomas aided by selective arterial secretin injection test and intraoperative secretin test. Ann Surg 1989;210:710–718PubMed

15.

Lairmore TC, Piersall LD, DdeBenedetti MK, et al. Clinical genetic testing and early surgical intervention in patients with multiple endocrine neoplasia type 1 (MEN1). Ann Surg 2004;239:637–647PubMed

16.

Imamura M, Takahashi K. Use of selective arterial secretin injection test to guide surgery in patients with Zollinger-Ellison syndrome. World J Surg 1993;17:433–438PubMedCrossRef

17.

Imamura M. Establishment of a new strategy for gastrinomas based on the basic research on endocrine tumors. Formosan J Surg 1999;32:197–201

18.

Sarmiento JM, Farnell MB, Que FG, et al. Pancreaticoduodenectomy for islet tumors of the head of the pancreas. World J Surg 2002;26:1267–1271PubMedCrossRef

19.

Norton JA, Jensen RT. Resolved and unsolved controversies in the surgical management of patients with Zolinger-Ellison syndrome. Ann Surg 2004;240:757–773PubMed

20.

Krenning EP, Kwekkeboom DJ, Oei HY. Somatostatin receptor scintigraphy in gastroenteropancreatic tumors. Ann N Y Acad Sci 1994;733:41–424

21.

Clark OH. What’s new in endocrine surgery. J Am Coll Surg 1997;184:126–136PubMed

22.

Imamura M, Kanda M, Takahashi K, et al. Clinicopathological characteristics of duodenal microgastrinomas. World J Surg 1992;16:703–709PubMedCrossRef

23.

Pipeleers-Marichal M, Donow C, Heiz PU, et al. Pathologic aspects of gastrinomas in patients with Zollinger-Ellison syndrome with and without multiple endocrine neoplasia type 1. World J Surg 1993;17:481–488PubMedCrossRef

24.

Thompson NW. Current concepts in the surgical management of multiple endocrine neoplasia type 1 pancreatic-duodenal disease. Results in the treatment of 40 patients with Zollinger-Ellison syndrome, hypoglycemia or both. J Intern Med 1997;243:495–500

25.

Delcore R, Cheung LY, Friesen SR. Outcome of lymph node involvement in patients with the Zollinger-Ellison syndrome. Ann Surg 1988;208:291–298PubMed

26.

Gibril F, Venzon DJ, Ojeaburu JV, et al. Prospective study of the natural history of gastrinoma in patients with MEN-1: definition of an aggressive and a nonaggressive form. J Clin Endocrinol Metab 2001;86:5282–5293PubMedCrossRef

27.

Zogakis TG, Gibril F, Libutti SK, et al. Management and outcome of patients with sporadic gastrinoma arising in the duodenum. Ann Surg 2003;238:42–48PubMedCrossRef

28.

Imamura M, Adachi H, Takahashi K, et al. Gastrin release from gastrinoma cells stimulated with secretin. Dig Dis Sci 1982;27:1130–1136PubMedCrossRef

29.

Passaro E Jr, Basso N, Walsh JH. Calcium challenge in the Zollinger-Ellison syndrome. Surgery 1972;72:60–67PubMed

30.

Itami A, Kato M, Komoto I, et al. Human gastrinoma cells express calcium-sensing receptor. Life Sci 2001;70:119–127PubMedCrossRef

31.

Doppman JL, Miller DL, Chang R, et al. Gastrinomas:localization by means of selective intraarterial injection of secretin. Radiology 1990;174:25–29PubMed

32.

Wada M, Komoto I, Doi R, et al. Intravenous calcium injection test is a novel complementary procedure in differential diagnosis for gastrinoma. World J Surg 2002;26:1291–1299PubMedCrossRef

33.

Turner LLO, Wren AM, Jackson JE, et al. Localization of gastrinomas by selective intra-arterial calcium injection. Clin Endocrinol 2002;57:821–825CrossRef

34.

Noda S, Norton JA, Jensen RT, et al. Surgical resection of intracardiac gastrinoma. Ann Thorac Surg 1999;67:532–553PubMedCrossRef

35.

Kato M, Imamura M, Hosotani R, et al. Curative resection of microgastrinomas based on the intraoperative secretin test. World J Surg 2000;24:1425–1430PubMed

36.

Chen H, Hardare JM, Uzar A, et al. Isolated liver metastases from neroendocrine tumors: does resection prolong survival? J Am Coll Surg 1998;187:88–93PubMedCrossRef

37.

Okuzawa A, Kobayashi S, Sakamoto K, et al. Metastatic gastrinoma to the liver after primary resection. J Gastroenterol 2000;35:717–720PubMedCrossRef

38.

Fraker DL, Norton JA, Alexander HR, et al. Surgery in Zollinger-Ellison syndrome alters the natural history of gastrinoma. Ann Surg 1994;220:320–330PubMed

39.

Imamura M, Komoto I, Doi R, et al. New pancreas-preserving total duodenectomy technique. World J Surg 2005;29:203–207PubMed

40.

Chung RS, Church JM, Stolk R. Pancreas-sparing duodenectomy: indications, surgical technique, and results. Surgery 1995;117:254–259PubMed

Title: Changing Treatment Strategy for Gastrinoma in Patients with Zollinger-Ellison Syndrome
Authors: Masayuki Imamura, MD
Izumi Komoto, MD
Shuichi Ota, MD
Publication date: 01-01-2006
Publisher: Springer-Verlag
Published in: World Journal of Surgery / Issue 1/2006
Print ISSN: 0364-2313
Electronic ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-005-0341-1

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Changing Treatment Strategy for Gastrinoma in Patients with Zollinger-Ellison Syndrome

Abstract

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