Published in:
01-01-2005 | Clinical Review
Current and Future Concepts of Abdominal Sepsis
Authors:
Klaus Emmanuel, M.D., Heike Weighardt, Ph.D., Holger Bartels, M.D., Jorg-Rudiger Siewert, M.D., Bernhard Holzmann, M.D.
Published in:
World Journal of Surgery
|
Issue 1/2005
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Excerpt
Severe sepsis is still a major cause of postoperative morbidity and mortality after abdominal surgery. Despite recent progress in understanding the immune conditions of abdominal sepsis, there is a high postoperative incidence (9-12%) and lethality (42-80%) caused by septic complications after major visceral surgery. Therefore, many aspects of the pathophysiology and immunology of sepsis need further elucidation. In particular, a number of studies have of investigated clinical and immunologic parameters to determine the risk of the development and lethal outcome of postoperative abdominal infection. …