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Published in: Aesthetic Plastic Surgery 1/2018

01-02-2018 | Original Article

Autologous Buccal Micro-Mucosa Free Graft combined with Posterior Scrotal Flap Transfer for Vaginoplasty in Male-To-Female Transsexuals: A Pilot Study

Authors: Shu-Yi Wei, Feng-Yong Li, Qiang Li, Sen-Kai Li, Chuan-De Zhou, Yu Zhou, Yu-Jiao Cao, Si-Ya Zhang, Yang Zhao

Published in: Aesthetic Plastic Surgery | Issue 1/2018

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Abstract

Background

The inverted peno-scrotal flap method is considered the standard method of vaginoplasty in male-to-female genital reassignment surgery. Though with numerous advantages, the method has its limitations regarding skin texture, lack of inherent lubrication, and that the tissues for creating the labia depend on the amount of tissues remaining after vaginoplasty. Our purpose was to describe the procedure and outcome of vaginoplasty applying a new technique: autologous buccal micro-mucosa free graft combined with posterior scrotal flap transfer, which could solve some of the problems the previous methods had.

Methods

Nine male-to-female transsexual patients received our new method of vaginoplasty from July 2010–October 2015. We described the details of the surgical procedure and evaluated the long-term anatomical and functional outcomes.

Results

In a mean clinical follow-up period of 25.3 months and phone interview follow-up of 50.3 months, we observed that the neovaginas in the nine cases were all of sufficient volume, lined with mucosa, with natural mucosal discharge. The oral donor sites resulted in no visible scars or malfunction. Eight patients experienced uneventful postoperative periods, while one patient suffered from scrotal flap prolapse. All the patients were sexually active and reported sexual satisfaction, with no need of lubrication.

Conclusion

The reported technique achieves the outcomes of creating a neovagina of sufficient volume, without serious stenosis in long-term follow-up. The neovagina is lined with mucosa and has appropriate lubrication as well as good sexual sensation. The reported method is easy and economical to perform and retains enough tissues for vulvoplasty to achieve a superior cosmetic appearance, with rare risk of complications and donor area malfunction. Additionally, this technique is feasible and advantageous to the patients who have insufficient peno-scrotal skin for neovaginal lining as well as those with unfavorable previous vaginoplasty. All of these indicate that this technique is a promising option for vaginoplasty in male-to-female transsexual surgery.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
Literature
1.
go back to reference Leclere FM, Casoli V, Baudet J, Weigert R (2015) Description of the Baudet surgical technique and introduction of a systematic method for training surgeons to perform male-to-female sex reassignment surgery. Aesthet Plast Surg 39:927–934CrossRef Leclere FM, Casoli V, Baudet J, Weigert R (2015) Description of the Baudet surgical technique and introduction of a systematic method for training surgeons to perform male-to-female sex reassignment surgery. Aesthet Plast Surg 39:927–934CrossRef
2.
go back to reference Kanhai RC (2016) Sensate vagina pedicled-spot for male-to-female transsexuals: the experience in the first 50 patients. Aesthet Plast Surg 40:284–287CrossRef Kanhai RC (2016) Sensate vagina pedicled-spot for male-to-female transsexuals: the experience in the first 50 patients. Aesthet Plast Surg 40:284–287CrossRef
3.
go back to reference Gennaro Selvaggi PC, De Cuypere Griet et al (2005) Gender identity disorder: general overview and surgical treatment for vaginoplasty in male-to-female transsexuals. Plast Reconstr Surg 116:135e–145eCrossRefPubMed Gennaro Selvaggi PC, De Cuypere Griet et al (2005) Gender identity disorder: general overview and surgical treatment for vaginoplasty in male-to-female transsexuals. Plast Reconstr Surg 116:135e–145eCrossRefPubMed
4.
5.
go back to reference Raigosa M, Avvedimento S, Yoon TS, Cruz-Gimeno J, Rodriguez G, Fontdevila J (2015) Male-to-female genital reassignment surgery: a retrospective review of surgical technique and complications in 60 patients. J Sex Med 12:1837–1845CrossRefPubMed Raigosa M, Avvedimento S, Yoon TS, Cruz-Gimeno J, Rodriguez G, Fontdevila J (2015) Male-to-female genital reassignment surgery: a retrospective review of surgical technique and complications in 60 patients. J Sex Med 12:1837–1845CrossRefPubMed
6.
go back to reference Fang RHCC, Ma S (1992) A new methods for clitoroplasty in male-to-female sex reassignment surgery. Plast Reconstr Surg 89:679–682CrossRefPubMed Fang RHCC, Ma S (1992) A new methods for clitoroplasty in male-to-female sex reassignment surgery. Plast Reconstr Surg 89:679–682CrossRefPubMed
7.
go back to reference Puppo V (2011) Embryology and anatomy of the vulva: the female orgasm and women’s sexual health. Eur J Obstet Gynecol Reprod Biol 154:3–8CrossRefPubMed Puppo V (2011) Embryology and anatomy of the vulva: the female orgasm and women’s sexual health. Eur J Obstet Gynecol Reprod Biol 154:3–8CrossRefPubMed
8.
go back to reference Zhang CY, Cui HX (2002) The female reproductive system. In: Zheng SJ, Huang Y, Wu JB (eds) The anotomy measurements of Chinese People. People’s Medical Publishing House, Beijing, pp 206–227 Zhang CY, Cui HX (2002) The female reproductive system. In: Zheng SJ, Huang Y, Wu JB (eds) The anotomy measurements of Chinese People. People’s Medical Publishing House, Beijing, pp 206–227
9.
go back to reference Cao Y, Li Q, Zhou C, Li F, Li S, Zhou Y (2015) Measurements of female genital appearance in Chinese adults seeking genital cosmetic surgery: a preliminary report from a gynecological center. Int Urogynecol J 26:729–735CrossRefPubMed Cao Y, Li Q, Zhou C, Li F, Li S, Zhou Y (2015) Measurements of female genital appearance in Chinese adults seeking genital cosmetic surgery: a preliminary report from a gynecological center. Int Urogynecol J 26:729–735CrossRefPubMed
10.
go back to reference Taylor GI, Townsend P, Corlett R (1979) Superiority of the deep circumflex iliac vessels as the supply for free groin flaps. Plast Reconstr Surg 64:745–759CrossRefPubMed Taylor GI, Townsend P, Corlett R (1979) Superiority of the deep circumflex iliac vessels as the supply for free groin flaps. Plast Reconstr Surg 64:745–759CrossRefPubMed
11.
go back to reference Millard DR Jr (1986) Tissue losses should be replaced in kind. In: Millard DR Jr (ed) Principalization of plastic surgery. Lippincott Williams & Wilkins Inc., Boston, pp 191–228 Millard DR Jr (1986) Tissue losses should be replaced in kind. In: Millard DR Jr (ed) Principalization of plastic surgery. Lippincott Williams & Wilkins Inc., Boston, pp 191–228
12.
go back to reference Lin WC (2003) Use of autologous buccal mucosa for vaginoplasty: a study of eight cases. Hum Reprod 18:604–607CrossRefPubMed Lin WC (2003) Use of autologous buccal mucosa for vaginoplasty: a study of eight cases. Hum Reprod 18:604–607CrossRefPubMed
13.
go back to reference Yesim Ozgenel G, Ozcan M (2003) Neovaginal construction with buccal mucosal grafts. Plast Reconstr Surg 111:2250–2254CrossRefPubMed Yesim Ozgenel G, Ozcan M (2003) Neovaginal construction with buccal mucosal grafts. Plast Reconstr Surg 111:2250–2254CrossRefPubMed
14.
go back to reference Zhao M, Li P, Li S, Li Q (2009) Use of autologous micro-mucosa graft for vaginoplasty in vaginal agenesis. Ann Plast Surg 63:645–649CrossRefPubMed Zhao M, Li P, Li S, Li Q (2009) Use of autologous micro-mucosa graft for vaginoplasty in vaginal agenesis. Ann Plast Surg 63:645–649CrossRefPubMed
15.
go back to reference Li FY, Xu YS, Zhou CD, Zhou Y, Li SK, Li Q (2014) Long-term outcomes of vaginoplasty with autologous buccal micro-mucosa. Obstet Gynecol 123:951–956CrossRefPubMed Li FY, Xu YS, Zhou CD, Zhou Y, Li SK, Li Q (2014) Long-term outcomes of vaginoplasty with autologous buccal micro-mucosa. Obstet Gynecol 123:951–956CrossRefPubMed
16.
go back to reference Wangjiraniran B, Selvaggi G, Chokrungvaranont P, Jindarak S, Khobunsongserm S, Tiewtranon P (2015) Male-to-female vaginoplasty: Preecha’s surgical technique. J Plast Surg Hand Surg 49:153–159CrossRefPubMed Wangjiraniran B, Selvaggi G, Chokrungvaranont P, Jindarak S, Khobunsongserm S, Tiewtranon P (2015) Male-to-female vaginoplasty: Preecha’s surgical technique. J Plast Surg Hand Surg 49:153–159CrossRefPubMed
17.
go back to reference Dekker JJ, Hage JJ, Karim RB, Bloemena E (2007) Do histologic changes in the skin-lined neovagina of male-to-female transsexuals really occur? Ann Plast Surg 59:546–549CrossRefPubMed Dekker JJ, Hage JJ, Karim RB, Bloemena E (2007) Do histologic changes in the skin-lined neovagina of male-to-female transsexuals really occur? Ann Plast Surg 59:546–549CrossRefPubMed
18.
go back to reference Morrison SD, Satterwhite T, Grant DW, Kirby J, Laub DR Sr, VanMaasdam J (2015) Long-term outcomes of rectosigmoid neocolporrhaphy in male-to-female gender reassignment surgery. Plast Reconstr Surg 136:386–394CrossRefPubMed Morrison SD, Satterwhite T, Grant DW, Kirby J, Laub DR Sr, VanMaasdam J (2015) Long-term outcomes of rectosigmoid neocolporrhaphy in male-to-female gender reassignment surgery. Plast Reconstr Surg 136:386–394CrossRefPubMed
19.
go back to reference Guerrissi JO, Belmonte J (2004) Surgical treatment of dry eye syndrome: conjunctival graft of the minor salivary gland. Craniofac Surg 15:6–10CrossRef Guerrissi JO, Belmonte J (2004) Surgical treatment of dry eye syndrome: conjunctival graft of the minor salivary gland. Craniofac Surg 15:6–10CrossRef
20.
go back to reference Cheung LKSN, Tideman H (1994) The epithelialization process of the temporalis myofascial flap in maxillary reconstruction. J Craniomaxillofac Surg 22:84CrossRef Cheung LKSN, Tideman H (1994) The epithelialization process of the temporalis myofascial flap in maxillary reconstruction. J Craniomaxillofac Surg 22:84CrossRef
21.
go back to reference Zhang ML, Wang CY, Chang ZD, Cao DX, Han X (1986) Microskin grafting. II. Clinical report. Burns Incl Therm Inj 12:544–548CrossRefPubMed Zhang ML, Wang CY, Chang ZD, Cao DX, Han X (1986) Microskin grafting. II. Clinical report. Burns Incl Therm Inj 12:544–548CrossRefPubMed
22.
go back to reference Mardovin WMS, Eppinger M, Finley RK (1992) Micrografts: the “super” expansion graft. J Burn Care Rehabil 13:556–559CrossRefPubMed Mardovin WMS, Eppinger M, Finley RK (1992) Micrografts: the “super” expansion graft. J Burn Care Rehabil 13:556–559CrossRefPubMed
23.
go back to reference Zhang ML, Chang ZD, Han X, Zhu M (1986) Microskin grafting. I animal experiments. Burns Incl Therm Inj 12:540–543CrossRefPubMed Zhang ML, Chang ZD, Han X, Zhu M (1986) Microskin grafting. I animal experiments. Burns Incl Therm Inj 12:540–543CrossRefPubMed
24.
go back to reference Lin SD, Lai CS, Chou CK, Tsai CW, Wu KF, Chang CW (1992) Microskin autograft with pigskin xenograft overlay: a preliminary report of studies on patients. Burns 18:321–325CrossRefPubMed Lin SD, Lai CS, Chou CK, Tsai CW, Wu KF, Chang CW (1992) Microskin autograft with pigskin xenograft overlay: a preliminary report of studies on patients. Burns 18:321–325CrossRefPubMed
25.
go back to reference Dessy LA, Mazzocchi M, Corrias F, Ceccarelli S, Marchese C, Scuderi N (2014) The use of cultured autologous oral epithelial cells for vaginoplasty in male-to-female transsexuals: a feasibility, safety, and advantageousness clinical pilot study. Plast Reconstr Surg 133:158–161CrossRefPubMed Dessy LA, Mazzocchi M, Corrias F, Ceccarelli S, Marchese C, Scuderi N (2014) The use of cultured autologous oral epithelial cells for vaginoplasty in male-to-female transsexuals: a feasibility, safety, and advantageousness clinical pilot study. Plast Reconstr Surg 133:158–161CrossRefPubMed
26.
go back to reference Grafenberg E (1950) The role of urethra in female orgasm. Int J Sexol 3:145–148 Grafenberg E (1950) The role of urethra in female orgasm. Int J Sexol 3:145–148
Metadata
Title
Autologous Buccal Micro-Mucosa Free Graft combined with Posterior Scrotal Flap Transfer for Vaginoplasty in Male-To-Female Transsexuals: A Pilot Study
Authors
Shu-Yi Wei
Feng-Yong Li
Qiang Li
Sen-Kai Li
Chuan-De Zhou
Yu Zhou
Yu-Jiao Cao
Si-Ya Zhang
Yang Zhao
Publication date
01-02-2018
Publisher
Springer US
Published in
Aesthetic Plastic Surgery / Issue 1/2018
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-017-0977-x

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