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Published in: Aesthetic Plastic Surgery 1/2015

01-02-2015 | Original Article

Classification of the Aging Lips: A Foundation for an Integrated Approach to Perioral Rejuvenation

Authors: Vincenzo Penna, G. Björn Stark, Matthias Voigt, Alexander Mehlhorn, Niklas Iblher

Published in: Aesthetic Plastic Surgery | Issue 1/2015

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Abstract

Background

Although perioral aging is highly individual with several distinct processes taking part simultaneously, there is scarce systematic information which helps to indicate the right rejuvenation approach among the multitude of proposed procedures. Existing data about perioral aging has not yet been transformed into a consistent therapeutic concept. The intention of this study was to provide a simple, yet reproducible classification and to offer appropriate rejuvenation approaches.

Methods

To identify reliable and constant landmarks of the ongoing process of perioral aging, 462 perioral photo documentations were morphometrically analyzed. Based upon the identified landmarks a two-dimensional classification was developed. The classification was validated by three plastic surgeons. Inter- and intra-rater reliability was calculated using Cohen’s kappa coefficient.

Results

Perioral aging can be broken down into changes of the lip shape and changes of the lip surface. Both processes can be classified into three stages each: Lip shape according to the shape in profile view, the lip length in relation to the frontal incisors, and the degree of vermilion inversion. Lip surface according to the presence and degree of radial wrinkles and the visibility of the structural elements Cupid’s bow, philtrum, and white roll. Inter-observer reliability was rated very good (kappa values between 0.819 and 0.963) and perfect for intra-observer reliability (1.0).

Conclusion

A better understanding of perioral aging leads to a simple classification for the aging lips. Using the classification helps to tailor an appropriate treatment to the individual patient and aids to achieve a natural rejuvenation result.

Level of Evidence IV

This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.​springer.​com/​00266.
Literature
1.
go back to reference Penna V et al (2009) The aging lip: a comparative histological analysis of age-related changes in the upper lip complex. Plast Reconstr Surg 124(2):624–628PubMedCrossRef Penna V et al (2009) The aging lip: a comparative histological analysis of age-related changes in the upper lip complex. Plast Reconstr Surg 124(2):624–628PubMedCrossRef
2.
go back to reference Iblher N et al (2008) Changes in the aging upper lip–a photomorphometric and MRI-based study (on a quest to find the right rejuvenation approach). J Plast Reconstr Aesthet Surg 61(10):1170–1176PubMedCrossRef Iblher N et al (2008) Changes in the aging upper lip–a photomorphometric and MRI-based study (on a quest to find the right rejuvenation approach). J Plast Reconstr Aesthet Surg 61(10):1170–1176PubMedCrossRef
3.
go back to reference Sforza C et al (2010) Age- and sex-related changes in three-dimensional lip morphology. Forensic Sci Int 200(1–3):182 e1–7 Sforza C et al (2010) Age- and sex-related changes in three-dimensional lip morphology. Forensic Sci Int 200(1–3):182 e1–7
4.
go back to reference Penna V et al (2010) Proving the effectiveness of the lip lift for treatment of the aging lip: a morphometric evaluation. Plast Reconstr Surg 126(2):83e–84ePubMedCrossRef Penna V et al (2010) Proving the effectiveness of the lip lift for treatment of the aging lip: a morphometric evaluation. Plast Reconstr Surg 126(2):83e–84ePubMedCrossRef
5.
go back to reference Cohen SR et al (2006) ArteFill: a long-lasting injectable wrinkle filler material–summary of the U.S. Food and Drug Administration trials and a progress report on 4- to 5-year outcomes. Plast Reconstr Surg 118(3 Suppl):64S–76S Cohen SR et al (2006) ArteFill: a long-lasting injectable wrinkle filler material–summary of the U.S. Food and Drug Administration trials and a progress report on 4- to 5-year outcomes. Plast Reconstr Surg 118(3 Suppl):64S–76S
6.
go back to reference Jacono AA (2008) A new classification of lip zones to customize injectable lip augmentation. Arch Facial Plast Surg 10(1):25–29PubMedCrossRef Jacono AA (2008) A new classification of lip zones to customize injectable lip augmentation. Arch Facial Plast Surg 10(1):25–29PubMedCrossRef
7.
go back to reference Sclafani AP (2005) Soft tissue fillers for management of the aging perioral complex. Facial Plast Surg 21(1):74–78PubMedCrossRef Sclafani AP (2005) Soft tissue fillers for management of the aging perioral complex. Facial Plast Surg 21(1):74–78PubMedCrossRef
8.
go back to reference Thaler MP, Ubogy ZI (2005) Artecoll: the Arizona experience and lessons learned. Dermatol Surg 31(11 Pt 2): 1566-1574; discussion 1575–1576 Thaler MP, Ubogy ZI (2005) Artecoll: the Arizona experience and lessons learned. Dermatol Surg 31(11 Pt 2): 1566-1574; discussion 1575–1576
9.
go back to reference Wise JB, Greco T (2006) Injectable treatments for the aging face. Facial Plast Surg 22(2):140–146PubMedCrossRef Wise JB, Greco T (2006) Injectable treatments for the aging face. Facial Plast Surg 22(2):140–146PubMedCrossRef
10.
go back to reference Kridel RW (2001) Acellular human dermis for facial soft tissue augmentation. Facial Plast Surg Clin North Am 9(3):413–437PubMed Kridel RW (2001) Acellular human dermis for facial soft tissue augmentation. Facial Plast Surg Clin North Am 9(3):413–437PubMed
12.
go back to reference Moscona RA, Fodor L (2009) A retrospective study on liquid injectable silicone for lip augmentation: long-term results and patient satisfaction. J Plast Reconstr Aesthet Surg 63(10):1694–1698PubMedCrossRef Moscona RA, Fodor L (2009) A retrospective study on liquid injectable silicone for lip augmentation: long-term results and patient satisfaction. J Plast Reconstr Aesthet Surg 63(10):1694–1698PubMedCrossRef
13.
go back to reference Verret DJ, Leach JL, Gilmore J (2006) Dual-porosity expanded polytetrafluoroethylene implants for lip, nasolabial groove, and melolabial groove augmentation. Arch Facial Plast Surg 8(6):423–425PubMedCrossRef Verret DJ, Leach JL, Gilmore J (2006) Dual-porosity expanded polytetrafluoroethylene implants for lip, nasolabial groove, and melolabial groove augmentation. Arch Facial Plast Surg 8(6):423–425PubMedCrossRef
14.
go back to reference Semchyshyn N, Sengelmann RD (2003) Botulinum toxin A treatment of perioral rhytides. Dermatol Surg 29(5):490–495; discussion 495 Semchyshyn N, Sengelmann RD (2003) Botulinum toxin A treatment of perioral rhytides. Dermatol Surg 29(5):490–495; discussion 495
15.
go back to reference Lowe NJ, Yamauchi P (2004) Cosmetic uses of botulinum toxins for lower aspects of the face and neck. Clin Dermatol 22(1):18–22PubMedCrossRef Lowe NJ, Yamauchi P (2004) Cosmetic uses of botulinum toxins for lower aspects of the face and neck. Clin Dermatol 22(1):18–22PubMedCrossRef
16.
go back to reference Langsdon PR, Milburn M, Yarber R (2000) Comparison of the laser and phenol chemical peel in facial skin resurfacing. Arch Otolaryngol Head Neck Surg 126(10):1195–1199PubMedCrossRef Langsdon PR, Milburn M, Yarber R (2000) Comparison of the laser and phenol chemical peel in facial skin resurfacing. Arch Otolaryngol Head Neck Surg 126(10):1195–1199PubMedCrossRef
17.
go back to reference Dijkema SJ, van der Lei B (2005) Long-term results of upper lips treated for rhytides with carbon dioxide laser. Plast Reconstr Surg 115(6):1731–1735PubMedCrossRef Dijkema SJ, van der Lei B (2005) Long-term results of upper lips treated for rhytides with carbon dioxide laser. Plast Reconstr Surg 115(6):1731–1735PubMedCrossRef
19.
go back to reference Pitanguy I et al (1987) Esthetic surgery of the aging lip. Compendium 8(6):460–463, 465 Pitanguy I et al (1987) Esthetic surgery of the aging lip. Compendium 8(6):460–463, 465
20.
go back to reference Hinderer UT (1995) Aging of the upper lip: a new treatment technique. Aesthetic Plast Surg 19(6):519–526PubMedCrossRef Hinderer UT (1995) Aging of the upper lip: a new treatment technique. Aesthetic Plast Surg 19(6):519–526PubMedCrossRef
21.
go back to reference Guerrissi JO, Sanchez LI (1993) An approach to the senile upper lip. Plast Reconstr Surg 92(6):1187–1191PubMedCrossRef Guerrissi JO, Sanchez LI (1993) An approach to the senile upper lip. Plast Reconstr Surg 92(6):1187–1191PubMedCrossRef
22.
24.
go back to reference Santanche P, Bonarrigo C (2004) Lifting of the upper lip: personal technique. Plast Reconstr Surg 113(6):1828–1835; discussion 1836–1837 Santanche P, Bonarrigo C (2004) Lifting of the upper lip: personal technique. Plast Reconstr Surg 113(6):1828–1835; discussion 1836–1837
25.
26.
go back to reference Altman DG (1991) Practical Statistics for Medical Research. Chapman & Hall/CRC, Boca Raton Altman DG (1991) Practical Statistics for Medical Research. Chapman & Hall/CRC, Boca Raton
27.
go back to reference Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33(1):159–174PubMedCrossRef Landis JR, Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33(1):159–174PubMedCrossRef
28.
go back to reference Kane MA et al (2012) Validation of a lip fullness scale for assessment of lip augmentation. Plast Reconstr Surg 129(5):822e–828ePubMedCrossRef Kane MA et al (2012) Validation of a lip fullness scale for assessment of lip augmentation. Plast Reconstr Surg 129(5):822e–828ePubMedCrossRef
29.
go back to reference Wollina U (2013) Perioral rejuvenation: restoration of attractiveness in aging females by minimally invasive procedures. Clin Interv Aging 8:1149–1155PubMedCentralPubMedCrossRef Wollina U (2013) Perioral rejuvenation: restoration of attractiveness in aging females by minimally invasive procedures. Clin Interv Aging 8:1149–1155PubMedCentralPubMedCrossRef
30.
go back to reference Loose NA, et al (2014) Anatomy and lip enhancement. E2e Master collection. vol 4. E2e Medical Publishing, Paris Loose NA, et al (2014) Anatomy and lip enhancement. E2e Master collection. vol 4. E2e Medical Publishing, Paris
31.
go back to reference Solish N, Swift A (2011) An open-label, pilot study to assess the effectiveness and safety of hyaluronic acid gel in the restoration of soft tissue fullness of the lips. J Drugs Dermatol 10(2):145–149PubMed Solish N, Swift A (2011) An open-label, pilot study to assess the effectiveness and safety of hyaluronic acid gel in the restoration of soft tissue fullness of the lips. J Drugs Dermatol 10(2):145–149PubMed
32.
go back to reference Trelles MA, Shohat M, Urdiales F (2011) Safe and effective one-session fractional skin resurfacing using a carbon dioxide laser device in super-pulse mode: a clinical and histologic study. Aesthetic Plast Surg. 35(1):31–42PubMedCrossRef Trelles MA, Shohat M, Urdiales F (2011) Safe and effective one-session fractional skin resurfacing using a carbon dioxide laser device in super-pulse mode: a clinical and histologic study. Aesthetic Plast Surg. 35(1):31–42PubMedCrossRef
33.
go back to reference Suryadevara AC (2008) Update on perioral cosmetic enhancement. Curr Opin Otolaryngol Head Neck Surg 16(4):347–351PubMedCrossRef Suryadevara AC (2008) Update on perioral cosmetic enhancement. Curr Opin Otolaryngol Head Neck Surg 16(4):347–351PubMedCrossRef
34.
go back to reference Perkins SW, Balikian R (2007) Treatment of perioral rhytids. Facial Plast Surg Clin North Am 15(4):409–414 vPubMedCrossRef Perkins SW, Balikian R (2007) Treatment of perioral rhytids. Facial Plast Surg Clin North Am 15(4):409–414 vPubMedCrossRef
35.
go back to reference Recupero WD, McCollough EG (2010) Comparison of lip enhancement using autologous superficial musculoaponeurotic system tissue and postauricular fascia in conjunction with lip advancement. Arch Facial Plast Surg 12(5):342–348PubMedCrossRef Recupero WD, McCollough EG (2010) Comparison of lip enhancement using autologous superficial musculoaponeurotic system tissue and postauricular fascia in conjunction with lip advancement. Arch Facial Plast Surg 12(5):342–348PubMedCrossRef
36.
go back to reference Leaf N, Firouz JS (2002) Lip augmentation with superficial musculoaponeurotic system grafts: report of 103 cases. Plast Reconstr Surg 109(1):319–326; discussion 327–328 Leaf N, Firouz JS (2002) Lip augmentation with superficial musculoaponeurotic system grafts: report of 103 cases. Plast Reconstr Surg 109(1):319–326; discussion 327–328
37.
go back to reference Citarella ER, Sterodimas A, Conde-Green A (2009) Lip rejuvenation using perioral myotomies and orbicularis oculi muscle as autologous filler. Plast Reconstr Surg 124(6):446e–448ePubMedCrossRef Citarella ER, Sterodimas A, Conde-Green A (2009) Lip rejuvenation using perioral myotomies and orbicularis oculi muscle as autologous filler. Plast Reconstr Surg 124(6):446e–448ePubMedCrossRef
38.
go back to reference Cartier H et al (2012) Perioral rejuvenation with a range of customized hyaluronic acid fillers: efficacy and safety over six months with a specific focus on the lips. J Drugs Dermatol 11(1 Suppl):s17–s26PubMed Cartier H et al (2012) Perioral rejuvenation with a range of customized hyaluronic acid fillers: efficacy and safety over six months with a specific focus on the lips. J Drugs Dermatol 11(1 Suppl):s17–s26PubMed
39.
go back to reference Fagien S (1999) Botox for the treatment of dynamic and hyperkinetic facial lines and furrows: adjunctive use in facial aesthetic surgery. Plast Reconstr Surg 103(2):701–713PubMedCrossRef Fagien S (1999) Botox for the treatment of dynamic and hyperkinetic facial lines and furrows: adjunctive use in facial aesthetic surgery. Plast Reconstr Surg 103(2):701–713PubMedCrossRef
40.
go back to reference Carruthers J, Carruthers A (2004) Botulinum toxin A in the mid and lower face and neck. Dermatol Clin 22(2):151–158PubMedCrossRef Carruthers J, Carruthers A (2004) Botulinum toxin A in the mid and lower face and neck. Dermatol Clin 22(2):151–158PubMedCrossRef
41.
go back to reference Kaplan SE et al (2007) The use of botulinum toxin A in perioral rejuvenation. Facial Plast Surg Clin North Am 15(4):415–421 v–viPubMedCrossRef Kaplan SE et al (2007) The use of botulinum toxin A in perioral rejuvenation. Facial Plast Surg Clin North Am 15(4):415–421 v–viPubMedCrossRef
42.
go back to reference Carruthers A et al (2010) Multicenter, randomized, parallel-group study of the safety and effectiveness of onabotulinumtoxinA and hyaluronic acid dermal fillers (24-mg/ml smooth, cohesive gel) alone and in combination for lower facial rejuvenation. Dermatol Surg 36(Suppl 4):2121–2134PubMedCrossRef Carruthers A et al (2010) Multicenter, randomized, parallel-group study of the safety and effectiveness of onabotulinumtoxinA and hyaluronic acid dermal fillers (24-mg/ml smooth, cohesive gel) alone and in combination for lower facial rejuvenation. Dermatol Surg 36(Suppl 4):2121–2134PubMedCrossRef
43.
go back to reference Ascher B et al (2010) International consensus recommendations on the aesthetic usage of botulinum toxin type A (Speywood Unit)–Part II: Wrinkles on the middle and lower face, neck and chest. J Eur Acad Dermatol Venereol 24(11):1285–1295PubMedCrossRef Ascher B et al (2010) International consensus recommendations on the aesthetic usage of botulinum toxin type A (Speywood Unit)–Part II: Wrinkles on the middle and lower face, neck and chest. J Eur Acad Dermatol Venereol 24(11):1285–1295PubMedCrossRef
44.
go back to reference Kane MA (2005) Botox injections for lower facial rejuvenation. Oral Maxillofac Surg Clin North Am 17(1):41–49 viPubMedCrossRef Kane MA (2005) Botox injections for lower facial rejuvenation. Oral Maxillofac Surg Clin North Am 17(1):41–49 viPubMedCrossRef
45.
go back to reference Klein AW (2004) Contraindications and complications with the use of botulinum toxin. Clin Dermatol 22(1):66–75PubMedCrossRef Klein AW (2004) Contraindications and complications with the use of botulinum toxin. Clin Dermatol 22(1):66–75PubMedCrossRef
46.
go back to reference Lehrer MS, Benedetto AV (2005) Botulinum toxin—an update on its use in facial rejuvenation. J Cosmet Dermatol 4:285–297PubMedCrossRef Lehrer MS, Benedetto AV (2005) Botulinum toxin—an update on its use in facial rejuvenation. J Cosmet Dermatol 4:285–297PubMedCrossRef
47.
go back to reference Lanigan S (2011) An observational study of a 24 mg/mL hyaluronic acid with pre-incorporated lidocaine for lip definition and enhancement. J Cosmet Dermatol 10(1):11–14PubMedCrossRef Lanigan S (2011) An observational study of a 24 mg/mL hyaluronic acid with pre-incorporated lidocaine for lip definition and enhancement. J Cosmet Dermatol 10(1):11–14PubMedCrossRef
48.
go back to reference Scarano A, Carinci F, Piattelli A (2009) Lip augmentation with a new filler (agarose gel): a 3-year follow-up study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108(2):e11–e15PubMedCrossRef Scarano A, Carinci F, Piattelli A (2009) Lip augmentation with a new filler (agarose gel): a 3-year follow-up study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108(2):e11–e15PubMedCrossRef
49.
go back to reference De Boulle K et al (2009) Lip augmentation and contour correction with a ribose cross-linked collagen dermal filler. J Drugs Dermatol 8(3 Suppl):1–8PubMed De Boulle K et al (2009) Lip augmentation and contour correction with a ribose cross-linked collagen dermal filler. J Drugs Dermatol 8(3 Suppl):1–8PubMed
50.
go back to reference Carruthers J et al (2010) Multicenter, randomized, parallel-group study of onabotulinumtoxinA and hyaluronic acid dermal fillers (24-mg/ml smooth, cohesive gel) alone and in combination for lower facial rejuvenation: satisfaction and patient-reported outcomes. Dermatol Surg 36(Suppl 4):2135–2145PubMedCrossRef Carruthers J et al (2010) Multicenter, randomized, parallel-group study of onabotulinumtoxinA and hyaluronic acid dermal fillers (24-mg/ml smooth, cohesive gel) alone and in combination for lower facial rejuvenation: satisfaction and patient-reported outcomes. Dermatol Surg 36(Suppl 4):2135–2145PubMedCrossRef
51.
go back to reference Trussler AP et al (2008) Upper lip augmentation: palmaris longus tendon as an autologous filler. Plast Reconstr Surg 121(3):1024–1032PubMedCrossRef Trussler AP et al (2008) Upper lip augmentation: palmaris longus tendon as an autologous filler. Plast Reconstr Surg 121(3):1024–1032PubMedCrossRef
52.
go back to reference Mojallal A et al (2009) Improvement of skin quality after fat grafting: clinical observation and an animal study. Plast Reconstr Surg 124(3):765–774PubMedCrossRef Mojallal A et al (2009) Improvement of skin quality after fat grafting: clinical observation and an animal study. Plast Reconstr Surg 124(3):765–774PubMedCrossRef
53.
go back to reference Christensen L et al (2005) Adverse reactions to injectable soft tissue permanent fillers. Aesthetic Plast Surg 29(1):34–48PubMedCrossRef Christensen L et al (2005) Adverse reactions to injectable soft tissue permanent fillers. Aesthetic Plast Surg 29(1):34–48PubMedCrossRef
54.
go back to reference Lombardi T et al (2004) Orofacial granulomas after injection of cosmetic fillers. Histopathologic and clinical study of 11 cases. J Oral Pathol Med 33(2):115–120PubMedCrossRef Lombardi T et al (2004) Orofacial granulomas after injection of cosmetic fillers. Histopathologic and clinical study of 11 cases. J Oral Pathol Med 33(2):115–120PubMedCrossRef
55.
go back to reference Wolfram D, Tzankov A, Piza-Katzer H (2006) Surgery for foreign body reactions due to injectable fillers. Dermatology 213(4):300–304PubMedCrossRef Wolfram D, Tzankov A, Piza-Katzer H (2006) Surgery for foreign body reactions due to injectable fillers. Dermatology 213(4):300–304PubMedCrossRef
56.
go back to reference Andre P et al (2005) Adverse reactions to dermal fillers: a review of European experiences. J Cosmet Laser Ther 7(3–4):171–176PubMedCrossRef Andre P et al (2005) Adverse reactions to dermal fillers: a review of European experiences. J Cosmet Laser Ther 7(3–4):171–176PubMedCrossRef
57.
go back to reference Magne P, Gallucci GO, Belser UC (2003) Anatomic crown width/length ratios of unworn and worn maxillary teeth in white subjects. J Prosthet Dent 89(5):453–461PubMedCrossRef Magne P, Gallucci GO, Belser UC (2003) Anatomic crown width/length ratios of unworn and worn maxillary teeth in white subjects. J Prosthet Dent 89(5):453–461PubMedCrossRef
Metadata
Title
Classification of the Aging Lips: A Foundation for an Integrated Approach to Perioral Rejuvenation
Authors
Vincenzo Penna
G. Björn Stark
Matthias Voigt
Alexander Mehlhorn
Niklas Iblher
Publication date
01-02-2015
Publisher
Springer US
Published in
Aesthetic Plastic Surgery / Issue 1/2015
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-014-0415-2

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