Skip to main content
Top
Published in: Aesthetic Plastic Surgery 5/2003

01-10-2003

Porcine Dermal Collagen (Permacol) for Facial Contour Augmentation: Preliminary Report

Author: Aydin Saray

Published in: Aesthetic Plastic Surgery | Issue 5/2003

Login to get access

Abstract

Soft tissue loss or damage can occur for various reasons, including trauma, surgery, and disease. Reconstruction of normal contours can be achieved by using either alloplastic implants or autogenous tissues. Permacol, a dermal replacement material derived from fibrous acellular porcine dermal collagen, has been used for restoration of soft-tissue contours in the face. Eight patients were treated with porcine collagen in an attempt to achieve a smooth contour and a natural feel. Clinically visible soft tissue defects were successfully covered and aesthetic results were satisfying. Transient swelling that subsided within a week was noted in all patients. Meticulous and aseptic technique is mandatory for Permacol use. With this limited experience, Permacol was successfully used as a filler implant in reconstruction of post-traumatic soft-tissue defects, correcting post-parotidectomy hallowing and secondary nasal surgery to cover osseocartilaginous irregularities. However, there is a potential risk of inflammation and skin contractures in thin-skinned patients when implants are placed superficially.
Literature
1.
go back to reference Achauer, BM, VanderKam, VM, Celiköz, B, Jacobson, DG 1998Augmentation of facial soft-tissue defects with Alloderm dermal graft.Ann Plast Surg41503PubMed Achauer, BM, VanderKam, VM, Celiköz, B, Jacobson, DG 1998Augmentation of facial soft-tissue defects with Alloderm dermal graft.Ann Plast Surg41503PubMed
2.
go back to reference Adedeji, OA, Bailey, CA, Varma, JS 2002Porcine dermal collagen graft in abdominal-wall reconstruction.Br J Plast Surg5585CrossRefPubMed Adedeji, OA, Bailey, CA, Varma, JS 2002Porcine dermal collagen graft in abdominal-wall reconstruction.Br J Plast Surg5585CrossRefPubMed
3.
go back to reference Alster, TS, West, TB 2000Human-derived and new synthetic injectable materials for soft-tissue augmentation: Current status and role in cosmetic surgery.Plast Reconstr Surg1052515 Alster, TS, West, TB 2000Human-derived and new synthetic injectable materials for soft-tissue augmentation: Current status and role in cosmetic surgery.Plast Reconstr Surg1052515
4.
go back to reference Barrington, JW, Edwards, G .Minimal access sling using PelvicolTM.Int J Urogynaecol J11V8 S122 Barrington, JW, Edwards, G .Minimal access sling using PelvicolTM.Int J Urogynaecol J11V8 S122
5.
go back to reference Belcher, HJCR, Zic, R 2001Adverse effect of porcine collagen interposition after trapezoidectomy. A comparative study.J Hand Surg (Br)26B159CrossRefPubMed Belcher, HJCR, Zic, R 2001Adverse effect of porcine collagen interposition after trapezoidectomy. A comparative study.J Hand Surg (Br)26B159CrossRefPubMed
6.
go back to reference Billings Jr, E, May Jr, JW 1989Historical review and present status of free fat graft autotransplantation in plastic and reconstructive surgery.Plast Reconstr Surg83368PubMed Billings Jr, E, May Jr, JW 1989Historical review and present status of free fat graft autotransplantation in plastic and reconstructive surgery.Plast Reconstr Surg83368PubMed
7.
go back to reference Castor, SA, To, WC, Papay, FA 1999Lip augmentation with Alloderm acellular dermal graft and fat autograft: A comparison with autologous fat injection.Aesth Plast Surg23218CrossRef Castor, SA, To, WC, Papay, FA 1999Lip augmentation with Alloderm acellular dermal graft and fat autograft: A comparison with autologous fat injection.Aesth Plast Surg23218CrossRef
8.
go back to reference Chiu, DTW, Edgerton, BW 1990Repair and grafting of dermis, fat, and fascia.McCarthy, JG eds. Plastic Surgery.WB SaundersPhiladelphia508526 Chiu, DTW, Edgerton, BW 1990Repair and grafting of dermis, fat, and fascia.McCarthy, JG eds. Plastic Surgery.WB SaundersPhiladelphia508526
9.
go back to reference Coleman, WP, Lawrence, N, Sherman, RN, Reed, RJ, Pinski, KS 1993Autologous collagen. Lipocytic dermal augmentation: A histopathologic study.J Dermatol Surg Oncol191032PubMed Coleman, WP, Lawrence, N, Sherman, RN, Reed, RJ, Pinski, KS 1993Autologous collagen. Lipocytic dermal augmentation: A histopathologic study.J Dermatol Surg Oncol191032PubMed
10.
go back to reference Erol, OO 2000Facial autologous soft-tissue contouring by adjunction of tissue cocktail injection (Micrograft and minigraft mixture of dermis, fascia, and fat).Plast Reconstr Surg1061375 Erol, OO 2000Facial autologous soft-tissue contouring by adjunction of tissue cocktail injection (Micrograft and minigraft mixture of dermis, fascia, and fat).Plast Reconstr Surg1061375
11.
go back to reference Griffiths, RW, Shakespeare, PG 1982Human dermal collagen allografts: A three year histopathological study.Br J Plast Surg35519PubMed Griffiths, RW, Shakespeare, PG 1982Human dermal collagen allografts: A three year histopathological study.Br J Plast Surg35519PubMed
12.
go back to reference Harper, C 2001Permacol™: clinical experience with a new biomaterial.Hosp Med6290PubMed Harper, C 2001Permacol™: clinical experience with a new biomaterial.Hosp Med6290PubMed
13.
go back to reference Holl-Allen, RTJ 1984Porcine dermal collagen implants in man.J R Coll Surg Edinb29151PubMed Holl-Allen, RTJ 1984Porcine dermal collagen implants in man.J R Coll Surg Edinb29151PubMed
14.
go back to reference Jackson, IT, Yavuzer, R 2000Hydroxyapatite cement: An alternative for craniofacial skeletal contour refinements.Br J Plast Surg5324PubMed Jackson, IT, Yavuzer, R 2000Hydroxyapatite cement: An alternative for craniofacial skeletal contour refinements.Br J Plast Surg5324PubMed
15.
go back to reference Kononas, TC, Bucky, LP, Hurley, C, May Jr, JW 1993The fate of suctioned and surgically removed fat after implantation for soft-tissue augmentation: A volumetric and histologic study in the rabbit.Plast Reconstr Surg91763 Kononas, TC, Bucky, LP, Hurley, C, May Jr, JW 1993The fate of suctioned and surgically removed fat after implantation for soft-tissue augmentation: A volumetric and histologic study in the rabbit.Plast Reconstr Surg91763
16.
go back to reference Little, JW 2002Applications of the classic dermal fat graft in primary and secondary facial rejuvenation.Plast Reconstr Surg109788 Little, JW 2002Applications of the classic dermal fat graft in primary and secondary facial rejuvenation.Plast Reconstr Surg109788
17.
go back to reference Nacul, AM, Nacul, AP, de Born, AG 1998Bioplastique as a complement in conventional plastic surgery.Aesth Plast Surg22444CrossRef Nacul, AM, Nacul, AP, de Born, AG 1998Bioplastique as a complement in conventional plastic surgery.Aesth Plast Surg22444CrossRef
18.
go back to reference Nicolle, FV, Matti, BA, Scamp, T 1992Dermal and fascial autografts in facial aesthetic surgery.Aesth Plast Surg16219 Nicolle, FV, Matti, BA, Scamp, T 1992Dermal and fascial autografts in facial aesthetic surgery.Aesth Plast Surg16219
19.
go back to reference Ruparelia, BA, GunasheelaSundar, K 2000Anterior and posterior vaginal collapse repairs with porcine skin collagen (Permacol™) implant.Int Urogynaecol J11FDP33 S45 Ruparelia, BA, GunasheelaSundar, K 2000Anterior and posterior vaginal collapse repairs with porcine skin collagen (Permacol™) implant.Int Urogynaecol J11FDP33 S45
20.
go back to reference Sevin, K, Askar, I, Saray, A, Yormuk, E 2000Exposure of high-density porous polyethylene (Medpor) used for contour restoration and treatment.Br J Oral Maxillofac Surg3844PubMed Sevin, K, Askar, I, Saray, A, Yormuk, E 2000Exposure of high-density porous polyethylene (Medpor) used for contour restoration and treatment.Br J Oral Maxillofac Surg3844PubMed
21.
go back to reference Sclafani, AP, Romo III, T 2000Biology and chemistry of facial implants.Facial Plast Surg163PubMed Sclafani, AP, Romo III, T 2000Biology and chemistry of facial implants.Facial Plast Surg163PubMed
22.
go back to reference Sclafani, AP, Romo III, T, Parker, A, McCormick, SA, Cocker, R, Jacono, A 2002Homologous collagen dispersion (Dermalogen) as a dermal filler: Persistence and histology compared with bovine collagen.Ann Plast Surg49181CrossRefPubMed Sclafani, AP, Romo III, T, Parker, A, McCormick, SA, Cocker, R, Jacono, A 2002Homologous collagen dispersion (Dermalogen) as a dermal filler: Persistence and histology compared with bovine collagen.Ann Plast Surg49181CrossRefPubMed
23.
go back to reference Ward, BB, Feinberg, SE, Friedman, CD 2002Tissue matrices for soft tissue and mucosal augmentation and replacement.Facial Plast Surg183CrossRefPubMed Ward, BB, Feinberg, SE, Friedman, CD 2002Tissue matrices for soft tissue and mucosal augmentation and replacement.Facial Plast Surg183CrossRefPubMed
Metadata
Title
Porcine Dermal Collagen (Permacol) for Facial Contour Augmentation: Preliminary Report
Author
Aydin Saray
Publication date
01-10-2003
Publisher
Springer-Verlag
Published in
Aesthetic Plastic Surgery / Issue 5/2003
Print ISSN: 0364-216X
Electronic ISSN: 1432-5241
DOI
https://doi.org/10.1007/s00266-003-3012-3

Other articles of this Issue 5/2003

Aesthetic Plastic Surgery 5/2003 Go to the issue