Skip to main content
Top
Published in: International Orthopaedics 5/2021

01-05-2021 | Orthopaedic Heritage

The history of intramedullary nailing

Authors: Achilles Bekos, Spyridon Sioutis, Andreas Kostroglou, Theodosios Saranteas, Andreas F. Mavrogenis

Published in: International Orthopaedics | Issue 5/2021

Login to get access

Abstract

Purpose

To summarize the evolution of intramedullary nailing, highlight important milestones, introduce the atmosphere of the era concerning the first uses and development of intramedullary nailing, and present the status of nailing in modern international orthopaedics and traumatology.

Method

A thorough literature search was undertaken in PubMed and Google Scholar as well as in physical books in libraries to summarize the literature on the history and evolution of intramedullary nailing.

Results

The first use of an intramedullary device was attested in ancient Egypt; however, the first use of intramedullary nailing was reported in 1524 in Mexico, and the first medical journals reported on intramedullary nailing around the mid-1800s. The evolutions of intramedullary nailing including approach, material, cross-section and shape, and reaming technique occurred in the twentieth century. During the 1960s, intramedullary nailing was abandoned in favour of plate and screws osteosynthesis; however, in the 1970s, 1980s, and 1990s, a surge of novelties including flexible reaming, interlocking, and use of image intensification and titanium nails led to the advent of the second-generation intramedullary nailing. Today, intramedullary nailing has become the standard treatment of long bone fractures with low infection rates, small scars, excellent stabilization of the fractures, and immediate mobilization of the patients.

Conclusion

Intramedullary nailing has revolutionized the treatment of long bone fractures. However, with numerous nail designs, a lot of information on their efficacy is lacking. Considerably more work will need to be done to determine the optimal nail specifications.
Literature
1.
go back to reference Rosa N, Marta M, Vaz M et al (2019) Intramedullary nailing biomechanics: evolution and challenges. Proc Inst Mech Eng H 233:295–308PubMed Rosa N, Marta M, Vaz M et al (2019) Intramedullary nailing biomechanics: evolution and challenges. Proc Inst Mech Eng H 233:295–308PubMed
2.
go back to reference El Moumni M, Leenhouts PA, Ten Duis HJ, Wendt KW (2009) The incidence of non-union following unreamed intramedullary nailing of femoral shaft fractures. Injury 40:205–208PubMed El Moumni M, Leenhouts PA, Ten Duis HJ, Wendt KW (2009) The incidence of non-union following unreamed intramedullary nailing of femoral shaft fractures. Injury 40:205–208PubMed
3.
go back to reference Farill J (1952) Orthopedics in Mexico. J Bone Joint Surg Am 24(A):506–512PubMed Farill J (1952) Orthopedics in Mexico. J Bone Joint Surg Am 24(A):506–512PubMed
4.
go back to reference Markatos K, Mavrogenis A, Brilakis E et al (2019) Abulcasis (936–1013): his work and contribution to orthopaedics. Int Orthop 43:2199–2203PubMed Markatos K, Mavrogenis A, Brilakis E et al (2019) Abulcasis (936–1013): his work and contribution to orthopaedics. Int Orthop 43:2199–2203PubMed
5.
go back to reference Mavrogenis AF, Markatos K, Saranteas T et al (2019) The history of microsurgery. Eur J Orthop Surg Traumatol 29:247–254PubMed Mavrogenis AF, Markatos K, Saranteas T et al (2019) The history of microsurgery. Eur J Orthop Surg Traumatol 29:247–254PubMed
6.
go back to reference Mavrogenis AF, Saranteas T, Markatos K et al (2019) Pharmacies for pain and trauma in ancient Greece. Int Orthop 43:1529–1536PubMed Mavrogenis AF, Saranteas T, Markatos K et al (2019) Pharmacies for pain and trauma in ancient Greece. Int Orthop 43:1529–1536PubMed
7.
go back to reference Markatos K, Karamanou M, Saranteas T, Mavrogenis AF (2019) Hallmarks of amputation surgery. Int Orthop 43:493–499PubMed Markatos K, Karamanou M, Saranteas T, Mavrogenis AF (2019) Hallmarks of amputation surgery. Int Orthop 43:493–499PubMed
8.
go back to reference Markatos K, Mavrogenis AF, Karamanou M, Androutsos G (2018) Pycnodysostosis: the disease of Henri de Toulouse-Lautrec. Eur J Orthop Surg Traumatol 28:1569–1572PubMed Markatos K, Mavrogenis AF, Karamanou M, Androutsos G (2018) Pycnodysostosis: the disease of Henri de Toulouse-Lautrec. Eur J Orthop Surg Traumatol 28:1569–1572PubMed
9.
go back to reference Markatos K, Androutsos G, Karamanou M et al (2018) Jean-Louis Petit (1674–1750): a pioneer anatomist and surgeon and his contribution to orthopaedic surgery and trauma surgery. Int Orthop 42:2003–2007PubMed Markatos K, Androutsos G, Karamanou M et al (2018) Jean-Louis Petit (1674–1750): a pioneer anatomist and surgeon and his contribution to orthopaedic surgery and trauma surgery. Int Orthop 42:2003–2007PubMed
10.
go back to reference Mavrogenis AF, Markatos K, Nikolaou V et al (2018) Congenital anomalies of the limbs in mythology and antiquity. Int Orthop 42:957–965PubMed Mavrogenis AF, Markatos K, Nikolaou V et al (2018) Congenital anomalies of the limbs in mythology and antiquity. Int Orthop 42:957–965PubMed
11.
go back to reference Markatos K, Korres D, Chytas D et al (2018) Apollonius of Citium (first century BC) and his work on the treatment of joint dislocations. Int Orthop 42:1191–1196PubMed Markatos K, Korres D, Chytas D et al (2018) Apollonius of Citium (first century BC) and his work on the treatment of joint dislocations. Int Orthop 42:1191–1196PubMed
12.
go back to reference Markatos K, Karamanou M, Tsourouflis G et al (2018) Ambroise Paré (1510–1590): on the diagnosis and treatment of shoulder dislocations. Int Orthop 42:215–218PubMed Markatos K, Karamanou M, Tsourouflis G et al (2018) Ambroise Paré (1510–1590): on the diagnosis and treatment of shoulder dislocations. Int Orthop 42:215–218PubMed
13.
go back to reference Korres D, Markatos K, Chytas D et al (2017) Injuries of the spine and of the spinal cord in the Hippocratic Corpus of medicine. Int Orthop 41:2627–2629PubMed Korres D, Markatos K, Chytas D et al (2017) Injuries of the spine and of the spinal cord in the Hippocratic Corpus of medicine. Int Orthop 41:2627–2629PubMed
14.
go back to reference Colton C (2013) Orthopaedic challenges in Ancient Egypt. Bone & Joint 360(2):2–7 Colton C (2013) Orthopaedic challenges in Ancient Egypt. Bone & Joint 360(2):2–7
17.
go back to reference Senn N (1893) I. A new method of direct fixation of the fragments in compound and ununited fractures. Ann Surg 18:125–151PubMedPubMedCentral Senn N (1893) I. A new method of direct fixation of the fragments in compound and ununited fractures. Ann Surg 18:125–151PubMedPubMedCentral
18.
go back to reference Bircher H (1886) Eine neue methode unmittelbarer retention bei fracturen der rohrenknochen. Arch Klin Chir 34:410–419 Bircher H (1886) Eine neue methode unmittelbarer retention bei fracturen der rohrenknochen. Arch Klin Chir 34:410–419
19.
go back to reference Gluck T (1890) Autoplastik-transplantation-implantation von Fremdkörpern. Klin Wschr 27:421–427 Gluck T (1890) Autoplastik-transplantation-implantation von Fremdkörpern. Klin Wschr 27:421–427
20.
go back to reference Contzen H (1987) Die entwicklung der marknagelung und des verriegelungsnagels. Aktuelle Traumatologie 17:250–252PubMed Contzen H (1987) Die entwicklung der marknagelung und des verriegelungsnagels. Aktuelle Traumatologie 17:250–252PubMed
21.
go back to reference Groves EWH (1918) Ununited fractures, with special reference to gunshot injuries and the use of bone grafting. BJS (Br J Surg) 6:203–247 Groves EWH (1918) Ununited fractures, with special reference to gunshot injuries and the use of bone grafting. BJS (Br J Surg) 6:203–247
22.
go back to reference Bong MR (2006) The history of intramedullary nailing. Bull NYU Hosp Jt Dis 64:4 Bong MR (2006) The history of intramedullary nailing. Bull NYU Hosp Jt Dis 64:4
23.
go back to reference Smith-Petersen MN, Cave EF, Vangorder GW (1931) Intracapsular fractures of the neck of femur: Treatment by internal fixation. Arch Surg 23:715–759 Smith-Petersen MN, Cave EF, Vangorder GW (1931) Intracapsular fractures of the neck of femur: Treatment by internal fixation. Arch Surg 23:715–759
25.
go back to reference Fischer AW, Maatz R (1942) Weitere erfahrungen mit der marknagelung nach Küntscher. Arch Klin Chir 203:531 Fischer AW, Maatz R (1942) Weitere erfahrungen mit der marknagelung nach Küntscher. Arch Klin Chir 203:531
27.
go back to reference Rehnberg SV (1947) Treatment of fractures and pseudarthroses with marrow nailing. Ann Chir Gynaec Fenn 36:2 Rehnberg SV (1947) Treatment of fractures and pseudarthroses with marrow nailing. Ann Chir Gynaec Fenn 36:2
28.
go back to reference Born CT, Pidgeon T, Taglang G (2014) 75 years of contemporary intramedullary nailing. J Orthop Trauma 28(Suppl 8):S1–S2PubMed Born CT, Pidgeon T, Taglang G (2014) 75 years of contemporary intramedullary nailing. J Orthop Trauma 28(Suppl 8):S1–S2PubMed
30.
go back to reference Marí R, Valverde Vilamala D, León García A, Guirro P, Marqués López F (2016) A technical note for extracting an incarcerated femoral Kuntscher nail. J Orthop Case Rep 6:10–12PubMedCentral Marí R, Valverde Vilamala D, León García A, Guirro P, Marqués López F (2016) A technical note for extracting an incarcerated femoral Kuntscher nail. J Orthop Case Rep 6:10–12PubMedCentral
31.
go back to reference Gerhard BG (1958) Kuntscher-the Kuntscher’s method of intramedullary fixation: J. Bone Joint Surg 40:17–26 Gerhard BG (1958) Kuntscher-the Kuntscher’s method of intramedullary fixation: J. Bone Joint Surg 40:17–26
32.
go back to reference Smith J, Greaves I, Porter K (2010) Oxford Desk Reference-major trauma. Oxford University Press Smith J, Greaves I, Porter K (2010) Oxford Desk Reference-major trauma. Oxford University Press
33.
go back to reference Muller ME (1961) Principes d’osteosynthese. Helv Chir Acta 28:198–206 Muller ME (1961) Principes d’osteosynthese. Helv Chir Acta 28:198–206
34.
go back to reference Müller ME, Allgöwer M, Willenegger H (2013) Technik der Operativen Frakturenbehandlung. Springer-Verlag Müller ME, Allgöwer M, Willenegger H (2013) Technik der Operativen Frakturenbehandlung. Springer-Verlag
35.
go back to reference DeCoster T (2012) A brief history of medullary nailing, New Mexico perspective. UNM Orthop Res J 1:16 DeCoster T (2012) A brief history of medullary nailing, New Mexico perspective. UNM Orthop Res J 1:16
36.
go back to reference Seligson D (2015) History of intramedullary nailing. In: Intramedullary nailing. Springer, pp 3–12 Seligson D (2015) History of intramedullary nailing. In: Intramedullary nailing. Springer, pp 3–12
37.
go back to reference Browner BD, Cole JD (1987) Current status of locked intramedullary nailing: a review. J Orthop Trauma 1:183PubMed Browner BD, Cole JD (1987) Current status of locked intramedullary nailing: a review. J Orthop Trauma 1:183PubMed
38.
go back to reference Dagrenat D, Kempf I (2002) Biomechanics of locked intramedullary fixation of fractures. In: Practice of Intramedullary Locked Nails. Springer, pp 43–49 Dagrenat D, Kempf I (2002) Biomechanics of locked intramedullary fixation of fractures. In: Practice of Intramedullary Locked Nails. Springer, pp 43–49
39.
go back to reference Thakur AJ (2015) Elements of francture fixation, 3rd edn. Elsevier Health Sciences, New Delhi, India Thakur AJ (2015) Elements of francture fixation, 3rd edn. Elsevier Health Sciences, New Delhi, India
40.
go back to reference Gimeno MS, Albareda JA, Vernet JC et al (1997) Biomechanical study of the Grosse-Kempf femoral nail. Int Orthop 21:115–118PubMedCentral Gimeno MS, Albareda JA, Vernet JC et al (1997) Biomechanical study of the Grosse-Kempf femoral nail. Int Orthop 21:115–118PubMedCentral
41.
go back to reference Russell TA (2011) Intramedullary nailing: evolutions of femoral intramedullary nailing: first to fourth generations. J Orthop Trauma 25:S135–S138PubMed Russell TA (2011) Intramedullary nailing: evolutions of femoral intramedullary nailing: first to fourth generations. J Orthop Trauma 25:S135–S138PubMed
42.
43.
go back to reference Brumback RJ, Uwagie-Ero S, Lakatos RP et al (1988) Intramedullary nailing of femoral shaft fracture. Part II: Fracture-healing with static interlocking fixations. J Bone Joint Surg Am 70:1453–1462PubMed Brumback RJ, Uwagie-Ero S, Lakatos RP et al (1988) Intramedullary nailing of femoral shaft fracture. Part II: Fracture-healing with static interlocking fixations. J Bone Joint Surg Am 70:1453–1462PubMed
44.
go back to reference Lee DB, Pohrelyuk I, Yaskiv O, Lee JC (2012) Gas nitriding and subsequent oxidation of Ti-6Al-4V alloys. Nanoscale Res Lett 7:21PubMedPubMedCentral Lee DB, Pohrelyuk I, Yaskiv O, Lee JC (2012) Gas nitriding and subsequent oxidation of Ti-6Al-4V alloys. Nanoscale Res Lett 7:21PubMedPubMedCentral
45.
go back to reference Wall EJ, Jain V, Vora V et al (2008) Complications of titanium and stainless steel elastic nail fixation of pediatric femoral fractures. JBJS 90:1305–1313 Wall EJ, Jain V, Vora V et al (2008) Complications of titanium and stainless steel elastic nail fixation of pediatric femoral fractures. JBJS 90:1305–1313
46.
go back to reference Morawska-Chochól A, Chlopek J, Szaraniec B et al (2015) Influence of the intramedullary nail preparation method on nail’s mechanical properties and degradation rate. Mater Sci Eng C 51:99–106 Morawska-Chochól A, Chlopek J, Szaraniec B et al (2015) Influence of the intramedullary nail preparation method on nail’s mechanical properties and degradation rate. Mater Sci Eng C 51:99–106
47.
go back to reference Vécsei V, Hajdu S, Negrin LL (2011) Intramedullary nailing in fracture treatment: history, science and Küntscher’s revolutionary influence in Vienna, Austria. Injury 42:S1–S5PubMed Vécsei V, Hajdu S, Negrin LL (2011) Intramedullary nailing in fracture treatment: history, science and Küntscher’s revolutionary influence in Vienna, Austria. Injury 42:S1–S5PubMed
48.
go back to reference Samiezadeh S, Avval PT, Fawaz Z, Bougherara H (2014) Biomechanical assessment of composite versus metallic intramedullary nailing system in femoral shaft fractures: a finite element study. Clin Biomech 29:803–810 Samiezadeh S, Avval PT, Fawaz Z, Bougherara H (2014) Biomechanical assessment of composite versus metallic intramedullary nailing system in femoral shaft fractures: a finite element study. Clin Biomech 29:803–810
49.
go back to reference Kojic N, Rangger C, Özgün C et al (2017) Carbon-Fibre-Reinforced PEEK radiolucent intramedullary nail for humeral shaft fracture fixation: technical features and a pilot clinical study. Injury 48:S8–S11PubMed Kojic N, Rangger C, Özgün C et al (2017) Carbon-Fibre-Reinforced PEEK radiolucent intramedullary nail for humeral shaft fracture fixation: technical features and a pilot clinical study. Injury 48:S8–S11PubMed
50.
go back to reference Li G, Zhang L, Wang L et al (2018) Dual modulation of bone formation and resorption with zoledronic acid-loaded biodegradable magnesium alloy implants improves osteoporotic fracture healing: an in vitro and in vivo study. Acta Biomater 65:486–500PubMed Li G, Zhang L, Wang L et al (2018) Dual modulation of bone formation and resorption with zoledronic acid-loaded biodegradable magnesium alloy implants improves osteoporotic fracture healing: an in vitro and in vivo study. Acta Biomater 65:486–500PubMed
51.
go back to reference Bhandari M, Schemitsch E, Jönsson A et al (2009) Gamma nails revisited: gamma nails versus compression hip screws in the management of intertrochanteric fractures of the hip: a meta-analysis. J Orthop Trauma 23:460–464PubMed Bhandari M, Schemitsch E, Jönsson A et al (2009) Gamma nails revisited: gamma nails versus compression hip screws in the management of intertrochanteric fractures of the hip: a meta-analysis. J Orthop Trauma 23:460–464PubMed
Metadata
Title
The history of intramedullary nailing
Authors
Achilles Bekos
Spyridon Sioutis
Andreas Kostroglou
Theodosios Saranteas
Andreas F. Mavrogenis
Publication date
01-05-2021
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 5/2021
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-021-04973-y

Other articles of this Issue 5/2021

International Orthopaedics 5/2021 Go to the issue