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International Orthopaedics
Published in: International Orthopaedics 4/2021

01-04-2021 | Magnetic Resonance Imaging | Original Paper

Meniscal scaffold for the treatment of partial meniscal defect—clinical and radiological outcomes in a two-year follow-up

Authors: Umer Butt, Filip Vuletić, Gregor Stenhouse, Damir Hudetz, Neil Bradbury

Published in: International Orthopaedics | Issue 4/2021

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Abstract

Purpose

The aim of meniscal scaffolds is to fill the defect, allow regeneration of meniscal-like tissues, and to prevent long-term risk of cartilage wear and tear. The aim of this study was to evaluate clinical results after two years and magnetic resonance imaging (MRI) results a year after implantation of a meniscal scaffold.

Methods

Fifteen patients were recruited into a prospective, single-arm, single-center study, and treated with meniscal scaffolds as a result of segmental meniscal defect due to previous partial meniscectomy. Patients were evaluated using functional knee scores used pre-operatively and 6, 12, and 24 months postoperatively. The radiological outcome was assessed using MRI at 12 months by evaluating scaffold size, morphology, and intensity according to the Genovese grading system. Cartilage assessment was completed according to The International Cartilage Repair Society (ICRS) score.

Results

All patients completed a follow-up of 24 months. A statistically significant increase in mean levels of all functional scores was present in all patients. On the MRI, all but one of the patients presented an incorporated meniscal implant. In most of the patients (73%), the meniscal implant was a Genovese type III. Type II and III signal intensities were present in all scaffolds when compared with the residual meniscal tissue. A stable cartilage (ICRS) status was observed in 80% of the patients compared with the pre-operative cartilage scores.

Conclusion

In our case series of patients treated with the meniscal scaffold implant, we observed good clinical results at a two year follow-up. Furthermore, MRI findings suggest that meniscal scaffolds might have a beneficial effect on articular cartilage.
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Metadata
Title
Meniscal scaffold for the treatment of partial meniscal defect—clinical and radiological outcomes in a two-year follow-up
Authors
Umer Butt
Filip Vuletić
Gregor Stenhouse
Damir Hudetz
Neil Bradbury
Publication date
01-04-2021
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 4/2021
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-020-04811-7

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