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International Orthopaedics

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01-06-2020 | Tranexamic Acid | Letter to the Editor

Comment on the article “The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial”

Author: Saubhik Das

Published in: International Orthopaedics | Issue 6/2020

Excerpt

To the Editor, …

Lei YT, Xie JW, Huang Q, Huang W, Pei FX (2020) The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial. Int Orthop 44(3):477–486. https://doi.org/10.1007/s00264-019-04469-w CrossRefPubMed

Xu S, Chen JY, Zheng Q et al (2019) The safest and most efficacious route of tranexamic acid administration in total joint arthroplasty: a systematic review and network meta-analysis. Thromb Res 176:61–66. https://doi.org/10.1016/j.thromres.2019.02.006 CrossRefPubMed

Fillingham YA, Ramkumar DB, Jevsevar DS et al (2018) The efficacy of Tranexamic acid in total knee arthroplasty: a network meta-analysis. J Arthroplasty 33(10):3090–3098.e1. https://doi.org/10.1016/j.arth.2018.04.043 CrossRefPubMed

Jain NP, Nisthane PP, Shah NA (2016) Combined administration of systemic and topical tranexamic acid for total knee arthroplasty: can it be a better regimen and yet safe? A randomized controlled trial. J Arthroplast 31(2):542–547. https://doi.org/10.1016/j.arth.2015.09.029 CrossRef

Nielsen CS, Jans Ø, Ørsnes T, Foss NB, Troelsen A, Husted H (2016) Combined intra-articular and intravenous tranexamic acid reduces blood loss in total knee arthroplasty: a randomized, double-blind, placebo-controlled trial. J Bone Joint Surg Am 98(10):835–841CrossRefPubMed

Tzatzairis TK, Drosos GI, Kotsios SE, Ververidis AN, Vogiatzaki TD, Kazakos KI (2016) Intravenous vs topical tranexamic acid in total knee arthroplasty without tourniquet application: a randomized controlled study. J Arthroplast 31(11):2465–2470. https://doi.org/10.1016/j.arth.2016.04.036 CrossRef

Sun Q, Li J, Chen J, Zheng C, Liu C, Jia Y (2019) Comparison of intravenous, topical or combined routes of tranexamic acid administration in patients undergoing total knee and hip arthroplasty: a meta-analysis of randomised controlled trials. BMJ Open 9(1):e024350. Published 2019 Jan 28. https://doi.org/10.1136/bmjopen-2018-024350 CrossRefPubMedPubMedCentral

Title: Comment on the article “The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial”
Author: Saubhik Das
Publication date: 01-06-2020
Publisher: Springer Berlin Heidelberg
Keyword: Tranexamic Acid
Published in: International Orthopaedics / Issue 6/2020
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI: https://doi.org/10.1007/s00264-020-04554-5

At a glance: The STEP trials

Springer Medicine

Comment on the article “The antifibrinolytic and anti-inflammatory effects of a high initial-dose tranexamic acid in total knee arthroplasty: a randomized controlled trial”

Excerpt

At a glance: The STEP trials

Springer Medicine

Excerpt

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