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International Orthopaedics

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01-03-2018 | Original Paper

Comparable outcome of culture-negative and culture-positive periprosthetic hip joint infection for patients undergoing two-stage revision

Authors: Jin Wang, Qiaojie Wang, Hao Shen, Xianlong Zhang

Published in: International Orthopaedics | Issue 3/2018

Abstract

Purpose

Lack of peri-operative microbiological evidence is an unfavourable factor in one-stage revision. The objective of this study was to figure out whether being culture-negative was an unfavourable factor for periprosthetic hip joint infection (PHJI) in patients undergoing two-stage revision.

Methods

Records of PHJI patients treated between October 2003 and December 2016 were reviewed at our institution. Information such as microbiological data, clinical outcomes, and other details of patients’ clinical courses were recorded.

Results

A total of the 58 cases were reviewed. The median follow-up duration was 68.5 months. The infection control rate of PHJI was 93.1% after two-stage revision. Kaplan–Meier analysis showed no significant difference in infection control rates between culture-negative and culture-positive groups. Culture-positive sinus secretions were significantly associated with an increased rate of reinfection (P = 0.039).

Conclusions

Two-stage revision had a high success rate for eradication of PHJI. Culture-negative PHJI had a comparable outcome with culture-positive PHJI.

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Title: Comparable outcome of culture-negative and culture-positive periprosthetic hip joint infection for patients undergoing two-stage revision
Authors: Jin Wang
Qiaojie Wang
Hao Shen
Xianlong Zhang
Publication date: 01-03-2018
Publisher: Springer Berlin Heidelberg
Published in: International Orthopaedics / Issue 3/2018
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI: https://doi.org/10.1007/s00264-018-3783-4

At a glance: The STEP trials

Springer Medicine

Comparable outcome of culture-negative and culture-positive periprosthetic hip joint infection for patients undergoing two-stage revision

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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