Skip to main content
Top
Published in: International Orthopaedics 9/2017

01-09-2017 | Original Paper

Comparison of intramedullary nail, plate, and external fixation in the treatment of distal tibia nonunions

Authors: Nabil A. Ebraheim, Brad Evans, Xiaochen Liu, Mina Tanios, Marshall Gillette, Jiayong Liu

Published in: International Orthopaedics | Issue 9/2017

Login to get access

Abstract

Purpose

The purpose of this study was to examine time to union of extra-articular distal tibia nonunions based on fracture type and fixation methods: intramedullary nail (IMN), plate osteosynthesis (PO), and external fixation (EF).

Methods

This retrospective chart review included all patients who presented at a Level I trauma center with AO/OTA 43A & distal third 42A-C fracture nonunions between 2008 and 2014. Fixation methods were recorded and patient course was followed until nonunion had healed clinically.

Results

Thirty-three distal tibia nonunions were included, and 29 reached eventual union (88%). Five AO/OTA fracture types were present. Mean times to union from nonunion diagnosis between original fracture types were compared (p = 0.203). Comminuted fracture types had longer times to union from nonunion diagnosis compared to simple fracture types (78 vs. 46 weeks, p = 0.051) and more revision fixations (1.5 vs. 0.5, p = 0.037). Mean time to union from nonunion diagnosis was shorter when no revision fixation was done compared to revisions (15 vs. 42 weeks, p = 0.102). Times to union from nonunion diagnosis without revision fixation were: IMN (12 weeks), PO (27 weeks), and EF (13 weeks) (p = 0.202). Times to union from definitive revision fixation were: IMN (17 weeks), PO (21 weeks), and EF (66 weeks) (p = 0.009), with EF taking significantly longer than both other methods. 21 patients (64%) underwent revision fixation. Revision fail rates were: IMN (0/6, 0%), PO (2/8, 25%), and EF (15/21, 71%). Time to union was longer in revisions that changed fixation method compared to revisions that used the same method (51 vs. 18 weeks, p = 0.030). Deep infections were also associated with longer union times (81 vs. 47 weeks, p = 0.040).

Conclusions

In this nonunion population, comminuted fracture types needed more time and revisions to reach union. Time to union was only clinically shorter when revision fixation was not performed, but IMN and PO were both successful fixation options with significantly shorter times to union than EF. Mean time to union increased even more when revision of fixation method was performed vs. exchange revision, as did nonunions with deep infections.
Literature
1.
go back to reference Tay WH, de Steiger R, Richardson M, Gruen R, Balogh ZJ (2014) Health outcomes of delayed union and nonunion of femoral and tibial shaft fractures. Injury 45:1653–8CrossRefPubMed Tay WH, de Steiger R, Richardson M, Gruen R, Balogh ZJ (2014) Health outcomes of delayed union and nonunion of femoral and tibial shaft fractures. Injury 45:1653–8CrossRefPubMed
2.
go back to reference Joveniaux P, Ohl X, Harisboure A et al (2010) Distal tibia fractures: management and complications of 101 cases. Int Orthop 34:583–8CrossRefPubMed Joveniaux P, Ohl X, Harisboure A et al (2010) Distal tibia fractures: management and complications of 101 cases. Int Orthop 34:583–8CrossRefPubMed
3.
go back to reference Piatkowski K, Piekarczyk P, Kwiatkowski K, Przybycien M, Chwedczuk B (2015) Comparison of different locking plate fixation methods in distal tibia fractures. Int Orthop 39:2245–51CrossRefPubMed Piatkowski K, Piekarczyk P, Kwiatkowski K, Przybycien M, Chwedczuk B (2015) Comparison of different locking plate fixation methods in distal tibia fractures. Int Orthop 39:2245–51CrossRefPubMed
4.
go back to reference Tarkin IS, Siska PA, Zelle BA (2010) Soft tissue and biomechanical challenges encountered with the management of distal tibia nonunions. Orthop Clin N Am 41:119–26CrossRef Tarkin IS, Siska PA, Zelle BA (2010) Soft tissue and biomechanical challenges encountered with the management of distal tibia nonunions. Orthop Clin N Am 41:119–26CrossRef
5.
go back to reference Avilucea FR, Sathiyakumar V, Greenberg SE et al (2015) Open distal tibial shaft fractures: a retrospective comparison of medial plate versus nail fixation. Eur J Trauma Emerg Surg 42(1):101–106 Avilucea FR, Sathiyakumar V, Greenberg SE et al (2015) Open distal tibial shaft fractures: a retrospective comparison of medial plate versus nail fixation. Eur J Trauma Emerg Surg 42(1):101–106
7.
go back to reference Fong K, Truong V, Foote CJ et al (2013) Predictors of nonunion and reoperation in patients with fractures of the tibia: an observational study. BMC Musculoskelet Discord 14:103CrossRef Fong K, Truong V, Foote CJ et al (2013) Predictors of nonunion and reoperation in patients with fractures of the tibia: an observational study. BMC Musculoskelet Discord 14:103CrossRef
8.
go back to reference Kruppa CG, Hoffmann MF, Sietsema DL, Mulder MB, Jones CB (2015) Outcomes after intramedullary nailing of distal tibial fractures. J Orthop Trauma 29:e309–15CrossRefPubMed Kruppa CG, Hoffmann MF, Sietsema DL, Mulder MB, Jones CB (2015) Outcomes after intramedullary nailing of distal tibial fractures. J Orthop Trauma 29:e309–15CrossRefPubMed
9.
go back to reference Tsang ST, Mills LA, Frantzias J, Baren JP, Keating JF, Simpson AH (2016) Exchange nailing for nonunion of diaphyseal fractures of the tibia: our results and an analysis of the risk factors for failure. Bone Joint J 98-B:534–41CrossRefPubMed Tsang ST, Mills LA, Frantzias J, Baren JP, Keating JF, Simpson AH (2016) Exchange nailing for nonunion of diaphyseal fractures of the tibia: our results and an analysis of the risk factors for failure. Bone Joint J 98-B:534–41CrossRefPubMed
10.
go back to reference Sugaya H, Mishima H, Aoto K et al (2014) Percutaneous autologous concentrated bone marrow grafting in the treatment for nonunion. Eur J Orthop Surg Tr 24:671–8CrossRef Sugaya H, Mishima H, Aoto K et al (2014) Percutaneous autologous concentrated bone marrow grafting in the treatment for nonunion. Eur J Orthop Surg Tr 24:671–8CrossRef
11.
go back to reference Cabrolier J, Molina M (2015) Is intramedullary nailing superior to plating in patients with extraarticular fracture of the distal tibia? Med Chem Commun 15:e6306 Cabrolier J, Molina M (2015) Is intramedullary nailing superior to plating in patients with extraarticular fracture of the distal tibia? Med Chem Commun 15:e6306
12.
go back to reference Fadel M, Ahmed MA, Al-Dars AM et al (2015) Ilizarov external fixation versus plate osteosynthesis in the management of extra-articular fractures of the distal tibia. Int Orthop 39:513–9CrossRefPubMed Fadel M, Ahmed MA, Al-Dars AM et al (2015) Ilizarov external fixation versus plate osteosynthesis in the management of extra-articular fractures of the distal tibia. Int Orthop 39:513–9CrossRefPubMed
13.
go back to reference Iqbal HJ, Pidikiti P (2013) Treatment of distal tibia metaphyseal fractures; plating versus intramedullary nailing: a systematic review of recent evidence. Foot Ankle Surg 19:143–147CrossRefPubMed Iqbal HJ, Pidikiti P (2013) Treatment of distal tibia metaphyseal fractures; plating versus intramedullary nailing: a systematic review of recent evidence. Foot Ankle Surg 19:143–147CrossRefPubMed
14.
go back to reference Vallier HA, Le TT, Bedi A (2008) Radiographic and clinical comparisons of distal ribia shaft fractures (4 to 11 cm proximal to the plafond): plating versus intramedullary nailing. J Orthop Trauma 22:207–311 Vallier HA, Le TT, Bedi A (2008) Radiographic and clinical comparisons of distal ribia shaft fractures (4 to 11 cm proximal to the plafond): plating versus intramedullary nailing. J Orthop Trauma 22:207–311
15.
go back to reference Vallier HA, Cureton BA, Patterson BM (2011) Randomized, prospective comparison of plate versus intramedullary nail fixation for distal tibia shaft fractures. J Orthop Trauma 25:736–741CrossRefPubMed Vallier HA, Cureton BA, Patterson BM (2011) Randomized, prospective comparison of plate versus intramedullary nail fixation for distal tibia shaft fractures. J Orthop Trauma 25:736–741CrossRefPubMed
16.
go back to reference Kwok CS, Crossman PT, Loizou CL (2014) Plate versus nail for distal tibial fractures: a systematic review and meta-analysis. J Orthop Trauma 28:542–8CrossRefPubMed Kwok CS, Crossman PT, Loizou CL (2014) Plate versus nail for distal tibial fractures: a systematic review and meta-analysis. J Orthop Trauma 28:542–8CrossRefPubMed
17.
go back to reference Mao Z, Wang G, Zhang L et al (2015) Intramedullary nailing versus plating for distal tibia fractures without articular involvement: a meta-analysis. J Orthop Surg Res 10:95CrossRefPubMedPubMedCentral Mao Z, Wang G, Zhang L et al (2015) Intramedullary nailing versus plating for distal tibia fractures without articular involvement: a meta-analysis. J Orthop Surg Res 10:95CrossRefPubMedPubMedCentral
18.
go back to reference Zhang QX, Gao FQ, Sun W, Wang YT, Yang YR, Li Z (2015) Minimally invasive percutaneous plate osteosynthesis versus open reduction and internal fixation for distal tibial fractures in adults: a meta-analysis. Zhongguo Gu Shang 28:757–62PubMed Zhang QX, Gao FQ, Sun W, Wang YT, Yang YR, Li Z (2015) Minimally invasive percutaneous plate osteosynthesis versus open reduction and internal fixation for distal tibial fractures in adults: a meta-analysis. Zhongguo Gu Shang 28:757–62PubMed
19.
go back to reference Zhou Y, Wang Y, Liu L, Zhou Z, Cao X (2015) Locking compression plate as an external fixator in the treatment of closed distal tibial fractures. Int Orthop 39:2227–37CrossRefPubMed Zhou Y, Wang Y, Liu L, Zhou Z, Cao X (2015) Locking compression plate as an external fixator in the treatment of closed distal tibial fractures. Int Orthop 39:2227–37CrossRefPubMed
20.
go back to reference Yu Y, Yu KH, Chen Y et al (2014) Comparison of three fixation methods for the treatment of tibial fractures in adolescents. Zhongguo Gu Shang 27:874–7PubMed Yu Y, Yu KH, Chen Y et al (2014) Comparison of three fixation methods for the treatment of tibial fractures in adolescents. Zhongguo Gu Shang 27:874–7PubMed
21.
go back to reference Shah SB, Mishra AK, Chalise P, Shah RK, Singh RP, Shrivatava MP (2014) Outcome of treatment of nonunion tibial shaft fracture by intramedullary interlocking nail augmentated with autogenous cancellous bone graft. Nepal Med Coll J 16:58–62PubMed Shah SB, Mishra AK, Chalise P, Shah RK, Singh RP, Shrivatava MP (2014) Outcome of treatment of nonunion tibial shaft fracture by intramedullary interlocking nail augmentated with autogenous cancellous bone graft. Nepal Med Coll J 16:58–62PubMed
22.
go back to reference Lonner JH, Koval KJ, Golyakhovsky V, Frankel VH (1995) Posttraumatic nonunion of the distal tibial metaphysis-Treatment using the Ilizarov circular external fixator. Am J Orthop Suppl 16–21 Lonner JH, Koval KJ, Golyakhovsky V, Frankel VH (1995) Posttraumatic nonunion of the distal tibial metaphysis-Treatment using the Ilizarov circular external fixator. Am J Orthop Suppl 16–21
23.
go back to reference Xu K, Fu X, Li YM, Wang CG, Li ZJ (2014) A treatment for large defects of the tibia caused by infected nonunion: ilizarov method with bone segment extension. Irish J Med Sci 183:423–8CrossRefPubMed Xu K, Fu X, Li YM, Wang CG, Li ZJ (2014) A treatment for large defects of the tibia caused by infected nonunion: ilizarov method with bone segment extension. Irish J Med Sci 183:423–8CrossRefPubMed
24.
go back to reference Zhao X, Wang PF, Zhang YT, Zhang CC, Xu SG, Zhang X (2014) Advanced bone graft combined with locking compression plate for the treatment of middle and distal tibia nonunion. Zhongguo Gu Shang 27:1008–11PubMed Zhao X, Wang PF, Zhang YT, Zhang CC, Xu SG, Zhang X (2014) Advanced bone graft combined with locking compression plate for the treatment of middle and distal tibia nonunion. Zhongguo Gu Shang 27:1008–11PubMed
25.
go back to reference Schoenleber SJ, Hutson JJ Jr (2015) Treatment of hypertrophic distal tibia nonunion and early malunion with callus distraction. Foot Ankle Int 36:400–7CrossRefPubMed Schoenleber SJ, Hutson JJ Jr (2015) Treatment of hypertrophic distal tibia nonunion and early malunion with callus distraction. Foot Ankle Int 36:400–7CrossRefPubMed
26.
go back to reference Marsh JL, Slongo TF, Agel J et al (2007) Fracture and dislocation classification compendium - 2007: orthopaedic trauma association classification, database and outcomes committee. J Orthop Trauma 21(10):S1–S163CrossRefPubMed Marsh JL, Slongo TF, Agel J et al (2007) Fracture and dislocation classification compendium - 2007: orthopaedic trauma association classification, database and outcomes committee. J Orthop Trauma 21(10):S1–S163CrossRefPubMed
27.
go back to reference IBM Corp (2012) IBM SPSS statistics for macintosh, version 21.0. IBM Corp, Armonk IBM Corp (2012) IBM SPSS statistics for macintosh, version 21.0. IBM Corp, Armonk
28.
go back to reference Metsemakers WJ, Roels N, Belmans A, Reynders P, Nijs S (2015) Risk factors for nonunion after intramedullary nailing of femoral shaft fractures: remaining controversies. Injury 46:1601–7CrossRefPubMed Metsemakers WJ, Roels N, Belmans A, Reynders P, Nijs S (2015) Risk factors for nonunion after intramedullary nailing of femoral shaft fractures: remaining controversies. Injury 46:1601–7CrossRefPubMed
29.
go back to reference Braly HL, O’Connor DP, Brinker MR (2013) Percutaneous autologous bone marrow injection in the treatment of distal meta-diaphyseal tibial nonunions and delayed unions. J Orthop Trauma 27:527–33CrossRefPubMed Braly HL, O’Connor DP, Brinker MR (2013) Percutaneous autologous bone marrow injection in the treatment of distal meta-diaphyseal tibial nonunions and delayed unions. J Orthop Trauma 27:527–33CrossRefPubMed
30.
go back to reference Zelle BA, Bhandari M, Espiritu M, Koval KJ, Zlowodzki M (2006) Treatment of distal tibia fractures without articular involvement: a systematic review of 1125 fractures. J Orthop Trauma 20:76–9CrossRefPubMed Zelle BA, Bhandari M, Espiritu M, Koval KJ, Zlowodzki M (2006) Treatment of distal tibia fractures without articular involvement: a systematic review of 1125 fractures. J Orthop Trauma 20:76–9CrossRefPubMed
31.
go back to reference Sathiyakumar V, Thakore RV, Ihejirika RC, Obremskey WT, Sethi MK (2014) Distal tibia fractures and medial plating: factors influending re-operation. Int Orthop 38:1483–8CrossRefPubMedPubMedCentral Sathiyakumar V, Thakore RV, Ihejirika RC, Obremskey WT, Sethi MK (2014) Distal tibia fractures and medial plating: factors influending re-operation. Int Orthop 38:1483–8CrossRefPubMedPubMedCentral
32.
go back to reference Richmond J, Colleran K, Borens O, Kloen P, Helfet DL (2004) Nonunions of the distal tibia treated by reamed intramedullary nailing. J Orthop Trauma 18:603–10CrossRefPubMed Richmond J, Colleran K, Borens O, Kloen P, Helfet DL (2004) Nonunions of the distal tibia treated by reamed intramedullary nailing. J Orthop Trauma 18:603–10CrossRefPubMed
33.
go back to reference Paraschou S, Bekir H, Anastasopoulos H et al (2009) Evaluation of interlocking intramedullary nailing in distal tibial fractures and nonunions. Acta Orthop Traumatol Turc 43:472–7CrossRefPubMed Paraschou S, Bekir H, Anastasopoulos H et al (2009) Evaluation of interlocking intramedullary nailing in distal tibial fractures and nonunions. Acta Orthop Traumatol Turc 43:472–7CrossRefPubMed
34.
go back to reference Wu CC (2011) Single-stage surgical treatment of infected nonunion of the distal tibia. J Orthop Trauma 25:156–61CrossRefPubMed Wu CC (2011) Single-stage surgical treatment of infected nonunion of the distal tibia. J Orthop Trauma 25:156–61CrossRefPubMed
35.
go back to reference Megas P, Saridis A, Kouzelis A, Kallivokas A, Mylonas S, Tyllianakis M (2010) The treatment of infected nonunion of the tibia following intramedullary nailing by the Ilizarov method. Injury 41:294–9CrossRefPubMed Megas P, Saridis A, Kouzelis A, Kallivokas A, Mylonas S, Tyllianakis M (2010) The treatment of infected nonunion of the tibia following intramedullary nailing by the Ilizarov method. Injury 41:294–9CrossRefPubMed
36.
go back to reference Litrenta J, Tornetta P 3rd, Vallier H et al (2015) Dynamizations and exchanges: success rates and indications. J Orthop Trauma 29:569–73CrossRefPubMed Litrenta J, Tornetta P 3rd, Vallier H et al (2015) Dynamizations and exchanges: success rates and indications. J Orthop Trauma 29:569–73CrossRefPubMed
37.
go back to reference Swanson EA, Garrard EC, O’Connor DP, Brinker MR (2015) Results of a systematic approach to exchange nailing for the treatment of aseptic tibial nonunions. J Orthop Trauma 29:28–35CrossRefPubMed Swanson EA, Garrard EC, O’Connor DP, Brinker MR (2015) Results of a systematic approach to exchange nailing for the treatment of aseptic tibial nonunions. J Orthop Trauma 29:28–35CrossRefPubMed
Metadata
Title
Comparison of intramedullary nail, plate, and external fixation in the treatment of distal tibia nonunions
Authors
Nabil A. Ebraheim
Brad Evans
Xiaochen Liu
Mina Tanios
Marshall Gillette
Jiayong Liu
Publication date
01-09-2017
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 9/2017
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-017-3432-3

Other articles of this Issue 9/2017

International Orthopaedics 9/2017 Go to the issue