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Published in: International Orthopaedics 5/2017

01-05-2017 | Original Paper

The cost of infection in severe open tibial fractures treated with a free flap

Authors: Ulrik Kähler Olesen, Nicolas Jones Pedersen, Henrik Eckardt, Line Lykke-Meyer, Christian Thorsten Bonde, Upender Martin Singh, Martin McNally

Published in: International Orthopaedics | Issue 5/2017

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Abstract

Purpose

Open tibial fractures needing soft tissue cover are challenging injuries. Infection risk is high, making treatment difficult and expensive. Delayed skin closure has been shown to increase the infection rate in several studies. We aimed at calculating the direct and indirect cost of treatment, and to determine the effect of delayed skin closure on this cost.

Methods

We reviewed all records of patients treated with a free flap in our institution for an open tibial fracture from 2002 to 2013. We calculated direct costs based on length of stay (LOS) and orthopaedic and plastic surgical procedures performed, including medications and intensive care. We analysed indirect cost in terms of absenteeism and unemployment benefits. The primary goal was to establish the extra cost incurred by an infection.

Results

We analysed 46 injuries in 45 patients. Infection increased the LOS from 41 to 74 days and increased the cost of treatment from € 49,817 in uninfected fractures to € 81,155 for infected fractures. Employed patients spent 430 days more on unemployment benefits, than a matched cohort in the background population. Achieving skin cover within seven days of injury decreased the infection rate from 60 to 27 %.

Conclusions

Severe open tibial fractures covered with free flaps, cause over a year of absenteeism. Infection increases direct cost of treatment over 60 % and roughly doubles LOS. Early soft-tissue cover and correct antibiotics have been shown to improve outcomes—underscoring the need for rapid referral to centres with an ortho-plastic set-up to handle such injuries.
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Footnotes
1
(60 × 81,155 + 40 × 49,817) / 100 = 68,620 (late group) (27 × 81,155 + 72 × 49,817) / 100 = 57,780 (early group) 68,620 - 57,780 = € 10,840 mean saving per patient.
 
Literature
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go back to reference Pedersen J (2014) Longitudinal risk assessment tool for sickness absence, unemployment, return to work and early retirement from the labour market. National Research Centre for the Working Environment, Copenhagen Pedersen J (2014) Longitudinal risk assessment tool for sickness absence, unemployment, return to work and early retirement from the labour market. National Research Centre for the Working Environment, Copenhagen
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go back to reference Herwaldt LA, Cullen JJ, Scholz D, French P, Zimmerman MB, Pfaller MA, Wenzel RP, Perl TM (2006) A prospective study of outcomes, healthcare resource utilization, and costs associated with postoperative nosocomial infections. Infect Control Hosp Epidemiol 27(12):1291–1298. http://www.ncbi.nlm.nih.gov/pubmed/17152025 Herwaldt LA, Cullen JJ, Scholz D, French P, Zimmerman MB, Pfaller MA, Wenzel RP, Perl TM (2006) A prospective study of outcomes, healthcare resource utilization, and costs associated with postoperative nosocomial infections. Infect Control Hosp Epidemiol 27(12):1291–1298. http://​www.​ncbi.​nlm.​nih.​gov/​pubmed/​17152025
Metadata
Title
The cost of infection in severe open tibial fractures treated with a free flap
Authors
Ulrik Kähler Olesen
Nicolas Jones Pedersen
Henrik Eckardt
Line Lykke-Meyer
Christian Thorsten Bonde
Upender Martin Singh
Martin McNally
Publication date
01-05-2017
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 5/2017
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-016-3337-6

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