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Published in: International Orthopaedics 7/2015

01-07-2015 | Original Paper

The influence of pre-existing radiographic osteoarthritis on functional outcome after trochanteric fracture

Authors: Christoph Kolja Boese, Benjamin Buecking, Tim Schwarting, Florian Debus, Steffen Ruchholtz, Christoph Bliemel, Michael Frink, Philipp Lechler

Published in: International Orthopaedics | Issue 7/2015

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Abstract

Purpose

It is crucially important to optimise functional outcome after fixation of trochanteric femoral fractures. While a number of risk factors that predict a poor clinical course have been identified, the influence of pre-existing radiographic osteoarthritis (OA) of the hip is unclear.

Methods

The influence of pre-existing radiographic OA of the hip on short- to mid-term functional outcome was prospectively analysed in a cohort of patients undergoing proximal femoral nailing for trochanteric fracture. OA was graded according to Kellgren and Lawrence; functional outcome was assessed at six and 12 months by the Harris hip score (HHS), the timed up and go (TUG) test and the Barthel Index.

Results

Our cohort comprised 188 patients (58 were male and 130 female), with a mean age of 82 years. At six and 12 months postoperatively, the HHS (p < 0.001 and p = 0.008, respectively) and Barthel Index (p < 0.001 and p = 0.02, respectively) correlated significantly with the grade of pre-existing OA. After adjustment for confounding variables, there was a significant association between the grade of pre-existing OA and the HHS at six months (p = 0.02). Although we observed trends suggestive of other relationships, none reached statistical significance.

Conclusions

Pre-existing radiographic OA of the hip is an important determinant of clinical outcome in elderly patients with a trochanteric femoral fracture. Further studies will be needed to establish the most effective means of restoring hip function after trochanteric femoral fracture in patients with radiographic OA of the hip.
Literature
1.
go back to reference Rosengren BE, Karlsson MK (2014) The annual number of hip fractures in Sweden will double from year 2002 to 2050: projections based on local and nationwide data. Acta Orthop 85(3):234–237PubMedCentralPubMedCrossRef Rosengren BE, Karlsson MK (2014) The annual number of hip fractures in Sweden will double from year 2002 to 2050: projections based on local and nationwide data. Acta Orthop 85(3):234–237PubMedCentralPubMedCrossRef
2.
go back to reference Kannegaard PN, van der Mark S, Eiken P, Abrahamsen B (2010) Excess mortality in men compared with women following a hip fracture. National analysis of comedications, comorbidity and survival. Age Ageing 39(2):203–209PubMedCrossRef Kannegaard PN, van der Mark S, Eiken P, Abrahamsen B (2010) Excess mortality in men compared with women following a hip fracture. National analysis of comedications, comorbidity and survival. Age Ageing 39(2):203–209PubMedCrossRef
3.
4.
go back to reference Talsnes O, Hjelmstedt F, Dahl OE, Pripp AH, Reikerås O (2011) Clinical and biochemical prediction of early fatal outcome following hip fracture in the elderly. Int Orthop 35(6):903–907PubMedCentralPubMedCrossRef Talsnes O, Hjelmstedt F, Dahl OE, Pripp AH, Reikerås O (2011) Clinical and biochemical prediction of early fatal outcome following hip fracture in the elderly. Int Orthop 35(6):903–907PubMedCentralPubMedCrossRef
5.
go back to reference Giessauf C, Glehr M, Bernhardt GA, Seibert FJ, Gruber K, Sadoghi P, Leithner A, Gruber G (2012) Quality of life after pertrochanteric femoral fractures treated with a γ nail: a single center study of 62 patients. BMC Musculoskelet Disord 13:214PubMedCentralPubMedCrossRef Giessauf C, Glehr M, Bernhardt GA, Seibert FJ, Gruber K, Sadoghi P, Leithner A, Gruber G (2012) Quality of life after pertrochanteric femoral fractures treated with a γ nail: a single center study of 62 patients. BMC Musculoskelet Disord 13:214PubMedCentralPubMedCrossRef
6.
go back to reference Radcliff TA, Regan E, Cowper Ripley DC, Hutt E (2012) Increased use of intramedullary nails for intertrochanteric proximal femoral fractures in veterans affairs hospitals: a comparative effectiveness study. J Bone Joint Surg Am 94(9):833–840PubMedCrossRef Radcliff TA, Regan E, Cowper Ripley DC, Hutt E (2012) Increased use of intramedullary nails for intertrochanteric proximal femoral fractures in veterans affairs hospitals: a comparative effectiveness study. J Bone Joint Surg Am 94(9):833–840PubMedCrossRef
7.
go back to reference Bonnaire F, Lein T, Bula P (2011) Trochanteric femoral fractures: anatomy, biomechanics and choice of implants. Unfallchirurg 114(6):491–500PubMedCrossRef Bonnaire F, Lein T, Bula P (2011) Trochanteric femoral fractures: anatomy, biomechanics and choice of implants. Unfallchirurg 114(6):491–500PubMedCrossRef
9.
go back to reference Roth T, Kammerlander C, Gosch M, Luger TJ, Blauth M (2010) Outcome in geriatric fracture patients and how it can be improved. Osteoporos Int 21:S615–S619PubMedCrossRef Roth T, Kammerlander C, Gosch M, Luger TJ, Blauth M (2010) Outcome in geriatric fracture patients and how it can be improved. Osteoporos Int 21:S615–S619PubMedCrossRef
10.
go back to reference Matre K, Vinje T, Havelin LI, Gjertsen JE, Furnes O, Espehaug B, Kjellevold SH, Fevang JM (2013) TRIGEN INTERTAN intramedullary nail versus sliding hip screw: a prospective, randomized multicenter study on pain, function, and complications in 684 patients with an intertrochanteric or subtrochanteric fracture and one year of follow-up. J Bone Joint Surg Am 95(3):200–208PubMedCrossRef Matre K, Vinje T, Havelin LI, Gjertsen JE, Furnes O, Espehaug B, Kjellevold SH, Fevang JM (2013) TRIGEN INTERTAN intramedullary nail versus sliding hip screw: a prospective, randomized multicenter study on pain, function, and complications in 684 patients with an intertrochanteric or subtrochanteric fracture and one year of follow-up. J Bone Joint Surg Am 95(3):200–208PubMedCrossRef
11.
go back to reference Hoffmann M, Hartel M, Rueger JM, Lehmann W (2014) Primary prosthetic replacement in per- and intertrochanteric fractures. Eur J Trauma Emerg Surg 40(3):273–277CrossRef Hoffmann M, Hartel M, Rueger JM, Lehmann W (2014) Primary prosthetic replacement in per- and intertrochanteric fractures. Eur J Trauma Emerg Surg 40(3):273–277CrossRef
12.
go back to reference Kim SY, Kim YG, Hwang JK (2005) Cementless calcar-replacement hemiarthroplasty compared with intramedullary fixation of unstable intertrochanteric fractures. A prospective, randomized study. J Bone Joint Surg Am 87(10):2186–2192PubMedCrossRef Kim SY, Kim YG, Hwang JK (2005) Cementless calcar-replacement hemiarthroplasty compared with intramedullary fixation of unstable intertrochanteric fractures. A prospective, randomized study. J Bone Joint Surg Am 87(10):2186–2192PubMedCrossRef
13.
go back to reference Shen J, Wang DL, Chen GX, Yang HL, Li L, Wei MX, Cai XQ, Yu ZH, Cheng L, Zhang XX, Zou TM (2012) Bipolar hemiarthroplasty compared with internal fixation for unstable intertrochanteric fractures in elderly patients. J Orthop Sci 17(6):722–729PubMedCrossRef Shen J, Wang DL, Chen GX, Yang HL, Li L, Wei MX, Cai XQ, Yu ZH, Cheng L, Zhang XX, Zou TM (2012) Bipolar hemiarthroplasty compared with internal fixation for unstable intertrochanteric fractures in elderly patients. J Orthop Sci 17(6):722–729PubMedCrossRef
14.
go back to reference Kim C, Linsenmeyer KD, Vlad S, Guermazi A, Clancy MM, Niu J, Felson DT (2014) Prevalence of radiographic and symptomatic hip osteoarthritis in an urban United States community: the Framingham osteoarthritis study. Arthritis Rheumatol 66(11):3013–3017. doi:10.1002/art.38795 PubMedCrossRef Kim C, Linsenmeyer KD, Vlad S, Guermazi A, Clancy MM, Niu J, Felson DT (2014) Prevalence of radiographic and symptomatic hip osteoarthritis in an urban United States community: the Framingham osteoarthritis study. Arthritis Rheumatol 66(11):3013–3017. doi:10.​1002/​art.​38795 PubMedCrossRef
15.
go back to reference Calderazzi F, Groppi G, Ricotta A, Ceccarelli F (2014) Does hip osteoarthritis have a protective effect against proximal femoral fractures? A retrospective study. Hip Int 24(3):231–236PubMed Calderazzi F, Groppi G, Ricotta A, Ceccarelli F (2014) Does hip osteoarthritis have a protective effect against proximal femoral fractures? A retrospective study. Hip Int 24(3):231–236PubMed
16.
go back to reference Hutchings L, Fox R, Chesser T (2011) Proximal femoral fractures in the elderly: how are we measuring outcome? Injury 42(11):1205–1213PubMedCrossRef Hutchings L, Fox R, Chesser T (2011) Proximal femoral fractures in the elderly: how are we measuring outcome? Injury 42(11):1205–1213PubMedCrossRef
17.
go back to reference Lechler P, Frink M, Gulati A, Murray D, Renkawitz T, Bücking B, Ruchholtz S, Boese CK (2014) The influence of hip rotation on femoral offset in plain radiographs. Acta Orthop 85(4):389–395PubMedCentralPubMedCrossRef Lechler P, Frink M, Gulati A, Murray D, Renkawitz T, Bücking B, Ruchholtz S, Boese CK (2014) The influence of hip rotation on femoral offset in plain radiographs. Acta Orthop 85(4):389–395PubMedCentralPubMedCrossRef
18.
go back to reference Pajarinen J, Lindahl J, Savolainen V, Michelsson O, Hirvensalo E (2004) Femoral shaft medialisation and neck-shaft angle in unstable pertrochanteric femoral fractures. Int Orthop 28(6):347–353PubMedCentralPubMed Pajarinen J, Lindahl J, Savolainen V, Michelsson O, Hirvensalo E (2004) Femoral shaft medialisation and neck-shaft angle in unstable pertrochanteric femoral fractures. Int Orthop 28(6):347–353PubMedCentralPubMed
19.
go back to reference Andruszkow H, Frink M, Frömke C, Matityahu A, Zeckey C, Mommsen P, Suntardjo S, Krettek C, Hildebrand F (2012) Tip apex distance, hip screw placement, and neck shaft angle as potential risk factors for cut-out failure of hip screws after surgical treatment of intertrochanteric fractures. Int Orthop 36(11):2347–2354PubMedCentralPubMedCrossRef Andruszkow H, Frink M, Frömke C, Matityahu A, Zeckey C, Mommsen P, Suntardjo S, Krettek C, Hildebrand F (2012) Tip apex distance, hip screw placement, and neck shaft angle as potential risk factors for cut-out failure of hip screws after surgical treatment of intertrochanteric fractures. Int Orthop 36(11):2347–2354PubMedCentralPubMedCrossRef
20.
go back to reference Reijman M, Hazes JM, Koes BW, Verhagen AP, Bierma-Zeinstra SM (2004) Validity, reliability, and applicability of seven definitions of hip osteoarthritis used in epidemiological studies: a systematic appraisal. Ann Rheum Dis 63(3):226–232PubMedCentralPubMedCrossRef Reijman M, Hazes JM, Koes BW, Verhagen AP, Bierma-Zeinstra SM (2004) Validity, reliability, and applicability of seven definitions of hip osteoarthritis used in epidemiological studies: a systematic appraisal. Ann Rheum Dis 63(3):226–232PubMedCentralPubMedCrossRef
Metadata
Title
The influence of pre-existing radiographic osteoarthritis on functional outcome after trochanteric fracture
Authors
Christoph Kolja Boese
Benjamin Buecking
Tim Schwarting
Florian Debus
Steffen Ruchholtz
Christoph Bliemel
Michael Frink
Philipp Lechler
Publication date
01-07-2015
Publisher
Springer Berlin Heidelberg
Published in
International Orthopaedics / Issue 7/2015
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-014-2663-9

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