Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
International Orthopaedics
Published in: International Orthopaedics 8/2010

01-12-2010 | Original Paper

Comparison of static and mobile antibiotic-impregnated cement spacers for the treatment of infected total knee arthroplasty

Authors: Sang-Jin Park, Eun-Kyoo Song, Jong-Keun Seon, Taek-Rim Yoon, Gi-Heon Park

Published in: International Orthopaedics | Issue 8/2010

Login to get access

Abstract

Infection after total knee arthroplasty (TKA) is a devastating complication, and two-stage reimplantation has evolved as an effective treatment option. This study was undertaken to compare the clinical results and radiological changes associated with static or mobile cement spacer placement for the treatment of infected TKA. Between July 2000 and February 2007, 36 consecutive patients were treated by two-stage reimplantation using antibiotic-impregnated cement spacers (AICS) for infected TKAs. Static spacers were used in 20 knees and mobile spacers in 16 knees. Clinical outcomes included success rates of TKR revisions, ranges of motion (ROM), and Hospital for Special Surgery knee scores (HSS), pain and function scores of the Knee Society (KS), joint exposure methods, and bone loss. In this study, mobile spacers provided better ranges of motion and functional knee scores without concomitant increases in infection rate and bone loss in the initial and mid-term periods.
Literature
1.
Anderson JA, Sculco PK, Heitkemper S, Mayman DJ, Bostrom MP, Sculco TP (2009) An articulating spacer to treat and mobilize patients with infected total knee arthroplasty. J Arthroplast 24(4):631–635CrossRef
2.
Antoci V, Phillips MJ, Antoci V Jr, Krackow KA (2009) The treatment of recurrent chronic infected knee arthroplasty with a 2-stage procedure. J Arthroplast 24(1):159.e13–17CrossRef
3.
Borden LS, Gearen PF (1987) Infected total knee arthroplasty: a protocol for management. J Arthroplast 2(1):27–36CrossRef
4.
Burnett RSJ, Kelly MA, Hanssen AD, Barrack RL (2007) Technique and timing of two-stage exchange for infection in TKA. Clin Orthop Relat Res 464:164–178PubMed
5.
Callaghan JJ, Katz RP, Johnston RC (1999) One-stage revision surgery of the infected hip. A minimum 10-year follow up study. Clin Orthop Relat Res 369:139–143CrossRefPubMed
6.
Emerson RH Jr, Muncie M, Tarbox TR, Higgins LL (2002) Comparison of a static with a mobile spacer in total knee infection. Clin Orthop Relat Res 404:132–138CrossRefPubMed
7.
Ewald FC (1989) The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. Clin Orthop Relat Res 248:9–12PubMed
8.
Fehring TK, Odum S, Calton TF, Mason JB (2000) Articulating versus static spacers in revision total knee arthroplasty. Clin Orthop Relat Res 380:9–16CrossRefPubMed
9.
Gristina AG, Kolkin J (1983) Current concepts review: total joint replacement and sepsis. J Bone Jt Surg Am 65:128–134
10.
Haddad FS, Masri BA, Campbell D et al (2000) The PROSTALAC functional spacer in two stage revision for infected knee replacements. Prosthesis of antibiotic-loaded acrylic cement. J Bone Jt Surg Br 82:807–812CrossRef
11.
Haleem AA, Berry DJ, Hanssen AD (2004) Mid-term to long-term followup of two-stage reimplantation for infected total knee arthroplasty. Clin Orthop Relat Res 428:35–39CrossRefPubMed
12.
Hofmann AA, Goldberg T, Tanner AM, Kurtin SM (2005) Treatment of infected total knee arthroplasty using an articulating spacer: 2- to 12-year experience. Clin Orthop Relat Res 430:125–131CrossRefPubMed
13.
Hsu YC, Cheng HC, Ng TP, Chiu KY (2007) Antibiotic-loaded cement articulating spacer for 2-stage reimplantation in infected total knee arthroplasty: a simple and economic method. J Arthroplast 22(7):1060–1066CrossRef
14.
Insall JN, Ranawat CS, Aglietti P, Shine J (1976) A comparison of four models of total knee replacement prostheses. J Bone Jt Surg Am 78:754–765
15.
16.
Masri BA, Duncan CP, Beauchamp CP (1998) Long-term elution of antibiotics from bone-cement: an in vivo study using the prosthesis of antibiotic-loaded acrylic cement (PROSTALAC) system. J Arthroplast 13(3):331–338CrossRef
17.
Meek RM, Masri BA, Dunlop D et al (2003) Patient satisfaction and functional status after treatment of infection at the site of a total knee arthroplasty with use of the PROSTALAC articulating spacer. J Bone Jt Surg Am 85:1888–1892
18.
Pitto RP, Castelli CC, Ferrari R, Munro J (2005) Pre-formed articulating knee spacer in two-stage revision for the infected total knee arthroplasty. Int Orthop 29:305–308CrossRefPubMed
19.
Windsor RE, Insall JN, Urs WK, Miller DV, Brause BD (1990) Two-stage reimplantation for the salvage of total knee arthroplasty complicated by infection. Further follow-up and refinement of indications. J Bone Jt Surg Am 2:272–278
Metadata
Title
Comparison of static and mobile antibiotic-impregnated cement spacers for the treatment of infected total knee arthroplasty
Authors
Sang-Jin Park
Eun-Kyoo Song
Jong-Keun Seon
Taek-Rim Yoon
Gi-Heon Park
Publication date
01-12-2010
Publisher
Springer-Verlag
Published in
International Orthopaedics / Issue 8/2010
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-009-0907-x

Other articles of this Issue 8/2010

International Orthopaedics 8/2010 Go to the issue

Original Paper

Prospective study of surgical delay for hip fractures: impact of an orthogeriatrician and increased trauma capacity

Original Paper

Prevalence of low back pain and lumbar spine degenerative disorders. Questionnaire survey and clinical–radiological analysis of a representative Hungarian population

Letter to the Editor

Comment on Xue et al.: Alendronate treatment improves bone–pedicle screw interface fixation in posterior lateral spine fusion: an experimental study in a porcine model

Original Paper

Potency of double-layered Poly L-lactic Acid scaffold in tissue engineering of tendon tissue

Original Paper

The UniSpacer™: correcting varus malalignment in medial gonarthrosis

Original Paper

In vivo experimental study of hat type cervical intervertebral fusion cage (HCIFC)