Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
International Orthopaedics
Published in: International Orthopaedics 2/2004

01-04-2004 | Original Paper

Augmentation in anterior cruciate ligament reconstruction—a histological and biomechanical study on goats

Authors: P. Buma, H. J. Kok, L. Blankevoort, W. Kuijpers, R. Huiskes, A. van Kampen

Published in: International Orthopaedics | Issue 2/2004

Login to get access

Abstract

We studied reconstruction of the anterior cruciate ligament (ACL) in skeletally mature goats. In one group, the autogenous tissue was augmented with polydioxanone (PDS), the other group had no augmentation. Histological complete incorporation and remodeling of the transplant was found in both groups. The newly formed connective tissues gradually assumed the microscopic properties of the normal ligament. The augmented group showed a delay in remodeling and maturation of the fiber bundles. Mechanically, the PDS-augmented transplants were stronger than the nonaugmented transplants immediately after surgery. During the first 6 weeks, a rapid decrease in strength of the augmented transplants was found, whereas the strength of the nonaugmented group gradually increased. The results of our experiment do not favor augmentation of autografts in reconstruction of the ACL.
Literature
1.
Amiel D, Kleiner JB, Akeson WH (1986) The natural history of the anterior cruciate ligament autograft of patellar tendon origin. Am J Sports Med 14:449-462PubMed
2.
Arnoczky SP (1983) Anatomy of the anterior cruciate ligament. Clin Orthop 172:19–25PubMed
3.
Asahina S, Yamamoto H, Muneta T, Ishibashi T, Furuya K (1995) Evaluation of anterior cruciate reconstruction reinforced by the Kennedy ligament augmentation device. An arthroscopic and histological study. Int Orthop 19:229–233PubMed
4.
Blauth W, Hassenpflug J (1985) Reconstruction of the cruciate ligament with special reference to synthetic substitute materials. Unfallchirurg 88:118-125PubMed
5.
Bolton CW, Bruchman WC (1985) The GORE-TEX expanded polytetrafluoroethylene prosthetic ligament. An in vitro and in vivo evaluation. Clin Orthop 196:202–213PubMed
6.
Bonnaire F, Berwarth H, Munst P, Eichinger S, Kuner EH (1995) Kann das Ergebnis nach Kreuzbandoperationen arthrometrisch erfasst werden? Ein Vergleich der subjektiven Einschatzung, des Lysholm-Scores, der klinischen Stabilitatseinstufung und der Stabilitatsmessung mit dem KT 1000 nach komplexen Kniebandverletzungen. Unfallchirurgie 21:83–91PubMed
7.
Claes L, Durselen L, Kiefer H, Mohr W (1987) The combined anterior cruciate and medial collateral ligament replacement by various materials: a comparative animal study. J Biomed Mater Res 21 [Suppl 3] 319–343
8.
Hehl G, Strecker W, Richter M, Kiefer H, Wissmeyer T (1999) Clinical experience with PDS-II augmentation for operative of acute proximal ACL ruptures—2-year follow-up. Knee Surg Sports Traumatol Arthrosc 7:102–106CrossRefPubMed
9.
Holzmuller W, Wehmeyer M, Rehm KE, Perren SM (1994) Histologische Untersuchungen zum Ersatz des vorderen Kreuzbands mit PDS-augmentierten Patellarsehnentransplantaten. Unfallchirurg 97:144–150PubMed
10.
Huang D, Chang TR, Aggarwal A, Lee RC, Ehrlich HP (1993) Mechanisms and dynamics of mechanical strengthening in ligament equivalent fibroblast populated collagen matrices. Ann Biomed Eng 21:289–305PubMed
11.
Lekic P, McCulloch CA (1996) Periodontal ligament cell population: the central role of fibroblasts in creating a unique tissue. Anat Rec 245:327–341CrossRefPubMed
12.
Margevicius KJ, Claes LE, Durselen L, Hanselmann K (1996) Identification and distribution of synthetic ligament wear particles in sheep. J Biomed Mater Res 31:319–328CrossRefPubMed
13.
McPherson GK, Mendenhall HV, Gibbons DF, Plenk H, Rottmann W, Sanford JB, Kennedy JC, Roth JH (1985) Experimental mechanical and histologic evaluation of the Kennedy ligament augmentation device. Clin Orthop 196:186–195PubMed
14.
Oberbillig C, Kirschner P (1989) Postoperative kontinuierliche passive Bewegung (CPM) nach Augmentation von vorderen Kreuzbandrupturen mit Polydioxanon-Bandern. Fruhergebnisse einer prospektiven Studie. Unfallchirurgie 15:145–151PubMed
15.
Puddu G, Cipolla M, Cerullo G, Franco V, Gianni E (1993) Anterior cruciate ligament reconstruction and augmentation with PDS graft. Clin Sports Med 12:13–24PubMed
16.
Ray JA, Doddi N, Regula D, Williams JA, Melveger A (1981) Polydioxanone (PDS), a novel monofilament synthetic absorbable suture. Surg Gynecol Obstet 153:497–507PubMed
17.
Rehm KE, Schultheis KH (1985) Ligament replacement with polydioxanone (PDS) Unfallchirurgie 11:264–273
18.
Tohyama H, Yasuka K (1998) Significance of graft tension in anterior cruciate ligament reconstruction. Basic background and clinical outcome. Knee Surg Sports Traumatol Arthrosc 6 [Suppl 1] 30–37
19.
Trager D, Pohle, K, Tschirner W (1995) Anterior cruciate ligament suture in comparison with plasty. A 5-year follow-up study. Arch Orthop Trauma Surg 114:278–280PubMed
20.
van Rens TJ (1977) Fixation of ligament structures in the knee. In: Injuries of ligaments and their repair, Chapchal G (ed), George Thieme, Stuttgart
21.
van Rens TJ, van den Berg AF, Huiskes R, Kuypers W (1986) Substitution of the anterior cruciate ligament: a long-term histologic and biomechanical study with autogenous pedicled grafts of the iliotibial band in dogs. Arthroscopy 2:139–154PubMed
22.
Wissing J, van Vroonhoven TJ, Schattenkerk ME, Veen HF, Ponsen RJ, Jeekel J (1987) Fascia closure after midline laparotomy: results of a randomized trial. Br J Surg 74:738–741PubMed
Metadata
Title
Augmentation in anterior cruciate ligament reconstruction—a histological and biomechanical study on goats
Authors
P. Buma
H. J. Kok
L. Blankevoort
W. Kuijpers
R. Huiskes
A. van Kampen
Publication date
01-04-2004
Publisher
Springer-Verlag
Published in
International Orthopaedics / Issue 2/2004
Print ISSN: 0341-2695
Electronic ISSN: 1432-5195
DOI
https://doi.org/10.1007/s00264-003-0515-0

Other articles of this Issue 2/2004

International Orthopaedics 2/2004 Go to the issue

Obituary

Professor Calogero Casuccio (1909–2003)

Original Paper

Distractible vertebral body replacement in patients with malignant vertebral destruction or osteoporotic burst fractures

Original Paper

The development of bone metastases as the first sign of metastatic spread in patients with primary solid tumours

Original Paper

Behaviour of the kyphotic angle in spinal tuberculosis

Original Paper

Radiological results of image-based and non-image-based computer-assisted total knee arthroplasty

Original Paper

Osteodensitometry after total hip replacement with uncemented taper-design stem