Published in:
01-12-2012 | Editorial Commentary
Pretreatment PET in breast cancer: is there a role?
Authors:
Sue Chua, Ashley M. Groves
Published in:
European Journal of Nuclear Medicine and Molecular Imaging
|
Issue 12/2012
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Excerpt
Breast carcinoma shows greater heterogeneity than the vast majority of adenocarcinomas and carries a highly variable prognosis dependent on a wide range of factors, including tumour size and stage, histological subtype, grade, hormone receptor status and a growing range of molecular abnormalities. Accurate preoperative prognostication is highly important in selecting the most appropriate individualized therapy for a particular patient, and considerable interest is now being focused on noninvasive imaging as a means to achieve this. The ability of
18F-FDG PET/CT to combine functional and anatomical data has contributed enormously to oncology [
1], and in particular to the emerging field of personalized medicine [
2], but it has not yet found a routine role in the preoperative assessment of breast cancer. We ask here whether this situation is likely to change. …