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European Journal of Nuclear Medicine and Molecular Imaging

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01-07-2009 | Focus on

Clinical applications of PET amyloid imaging: an update

Author: Giovanni Lucignani

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 7/2009

Excerpt

The biology of mind bridges the sciences -- concerned with the natural world -- and the humanities -- concerned with the meaning of human experience. Insights that come from this new synthesis will not only improve our understanding of psychiatric and neurological disorders, but will also lead to a deeper understanding of ourselves.

Eric R. Kandel

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Villemagne VL, Fodero-Tavoletti MT, Pike KE, Cappai R, Masters CL, Rowe CC. The ART of loss: Abeta imaging in the evaluation of Alzheimer's disease and other dementias. Mol Neurobiol. 2008;38(1):1–15.PubMedCrossRef

Small GW, Siddarth P, Burggren AC, Kepe V, Ercoli LM, Miller KJ, et al. Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia. Arch Gen Psychiatry. 2009;66(1):81–7.PubMedCrossRef

Braskie MN, Klunder AD, Hayashi KM, Protas H, Kepe V, Miller KJ, et al. Plaque and tangle imaging and cognition in normal aging and Alzheimer's disease. Neurobiol Aging. 2008 Nov 10. [Epub ahead of print]. doi:10.1016/j.neurobiolaging.2008.09.012.

http://www.loni.ucla.edu/approximatelythompson/FDDNP/video.html.

Grimmer T, Henriksen G, Wester HJ, Förstl H, Klunk WE, Mathis CA, et al. Clinical severity of Alzheimer's disease is associated with PIB uptake in PET. Neurobiol Aging. 2008 Mar 16. [Epub ahead of print] doi:10.1016/j.neurobiolaging.2008.01.016.

Fripp J, Bourgeat P, Acosta O, Raniga P, Modat M, Pike KE, et al. Appearance modeling of 11C PiB PET images: characterizing amyloid deposition in Alzheimer's disease, mild cognitive impairment and healthy aging. Neuroimage. 2008;43(3):430–9.PubMedCrossRef

Forsberg A, Engler H, Almkvist O, Blomquist G, Hagman G, Wall A, et al. PET imaging of amyloid deposition in patients with mild cognitive impairment. Neurobiol Aging. 2008;29(10):1456–65.PubMedCrossRef

Aizenstein HJ, Nebes RD, Saxton JA, Price JC, Mathis CA, Tsopelas ND, et al. Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol. 2008;65(11):1509–17.PubMedCrossRef

Jack CR Jr, Lowe VJ, Senjem ML, Weigand SD, Kemp BJ, Shiung MM, et al. 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain. 2008;131(Pt 3):665–80.PubMedCrossRef

10.

Ye L, Velasco A, Fraser G, Beach TG, Sue L, Osredkar T, et al. In vitro high affinity alpha-synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain. J Neurochem. 2008;105(4):1428–37.PubMedCrossRef

11.

Gomperts SN, Rentz DM, Moran E, Becker JA, Locascio JJ, Klunk WE, et al. Imaging amyloid deposition in Lewy body diseases. Neurology. 2008;71(12):903–10.PubMedCrossRef

12.

Edison P, Rowe CC, Rinne JO, Ng S, Ahmed I, Kemppainen N, et al. Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography. J Neurol Neurosurg Psychiatry. 2008;79(12):1331–8.PubMedCrossRef

13.

Maetzler W, Liepelt I, Reimold M, Reischl G, Solbach C, Becker C, et al. Cortical PIB binding in Lewy body disease is associated with Alzheimer-like characteristics. Neurobiol Dis. 2009;34(1):107–12.PubMedCrossRef

14.

Koivunen J, Verkkoniemi A, Aalto S, Paetau A, Ahonen JP, Viitanen M, et al. PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease. Brain. 2008;131(Pt 7):1845–53.PubMedCrossRef

15.

Remes AM, Laru L, Tuominen H, Aalto S, Kemppainen N, Mononen H, et al. Carbon 11-labeled Pittsburgh compound B positron emission tomographic amyloid imaging in patients with APP locus duplication. Arch Neurol. 2008;65(4):540–4.PubMedCrossRef

16.

Tolboom N, Yaqub M, van der Flier WM, Boellaard R, Luurtsema G, Windhorst AD, et al. Detection of Alzheimer pathology in vivo using both 11C-PIB and 18F-FDDNP PET. J Nucl Med. 2009;50(2):191–197.PubMedCrossRef

17.

Shin J, Lee SY, Kim SH, Kim YB, Cho SJ. Multitracer PET imaging of amyloid plaques and neurofibrillary tangles in Alzheimer's disease. Neuroimage. 2008;43(2):236–44.PubMedCrossRef

Title: Clinical applications of PET amyloid imaging: an update
Author: Giovanni Lucignani
Publication date: 01-07-2009
Publisher: Springer-Verlag
Published in: European Journal of Nuclear Medicine and Molecular Imaging / Issue 7/2009
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI: https://doi.org/10.1007/s00259-009-1148-3

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Clinical applications of PET amyloid imaging: an update

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