Skip to main content
Top
Published in: European Journal of Nuclear Medicine and Molecular Imaging 8/2008

01-08-2008 | Controversies

Is PET always an advantage versus planar and SPECT imaging?

Authors: Giuliano Mariani, Laura Bruselli, Adriano Duatti

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 8/2008

Login to get access

Excerpt

The article by Abass Alavi and Sandip Basu in this issue of the European Journal of Nuclear Medicine and Molecular Imaging vividly embodies, in a scenario that seems to be easy to reach, the expectations that imaging through positron emission tomography (PET) has raised in the nuclear medicine community at large. In Alavi’s view, this scenario resolutely points to soon-to-come wide availability of a complete armamentarium of PET radiopharmaceuticals capable of substituting virtually all of the single photon agents currently employed. Therefore, the most likely horizon that the author depicts for the future of diagnostic nuclear medicine is PET imaging, with dismal chances for both planar imaging and single photon computed tomography (SPECT) to even survive in the daily clinical routine [1]. …
Literature
1.
go back to reference Alavi A, Basu S. Planar and SPECT imaging in the era of PET and PET-CT: can it survive the test of time? Eur J Nucl Med Mol Imaging. 2008. Alavi A, Basu S. Planar and SPECT imaging in the era of PET and PET-CT: can it survive the test of time? Eur J Nucl Med Mol Imaging. 2008.
2.
go back to reference Rufini V, Calcagni ML, Baum RP. Imaging of neuroendocrine tumors. Semin Nucl Med. 2006;36:228–47.PubMedCrossRef Rufini V, Calcagni ML, Baum RP. Imaging of neuroendocrine tumors. Semin Nucl Med. 2006;36:228–47.PubMedCrossRef
3.
go back to reference Ravina B, Eidelberg D, Ahlskog JE, et al. The role of radiotracer imaging in Parkinson disease. Neurology. 2005;64:208–15.PubMed Ravina B, Eidelberg D, Ahlskog JE, et al. The role of radiotracer imaging in Parkinson disease. Neurology. 2005;64:208–15.PubMed
4.
go back to reference Seibyl JP, Chen W, Silverman DH. 3,4-dihydroxy-6-[18F]-fluoro-l-phenylalanine positron emission tomography in patients with central motor disorders and in evaluation of brain and other tumors. Semin Nucl Med. 2007;37(6):440–50. Nov.PubMedCrossRef Seibyl JP, Chen W, Silverman DH. 3,4-dihydroxy-6-[18F]-fluoro-l-phenylalanine positron emission tomography in patients with central motor disorders and in evaluation of brain and other tumors. Semin Nucl Med. 2007;37(6):440–50. Nov.PubMedCrossRef
5.
go back to reference Kowalski J, Henze M, Schuhmacher J, Macke HR, Hofmann M, Haberkorn U. Evaluation of positron emission tomography imaging using [68Ga]-DOTA-D Phe1-Tyr3-Octreotide in comparison to [111In]-DTPAOC SPECT. First results in patients with neuroendocrine tumors. Mol Imaging Biol. 2003;5:42–8.PubMedCrossRef Kowalski J, Henze M, Schuhmacher J, Macke HR, Hofmann M, Haberkorn U. Evaluation of positron emission tomography imaging using [68Ga]-DOTA-D Phe1-Tyr3-Octreotide in comparison to [111In]-DTPAOC SPECT. First results in patients with neuroendocrine tumors. Mol Imaging Biol. 2003;5:42–8.PubMedCrossRef
6.
go back to reference Watson E, Stabin M, Stubbs J. Dosimetry of technetium-94m-teboroxime. J Nucl Med. 1994;35:923–4.PubMed Watson E, Stabin M, Stubbs J. Dosimetry of technetium-94m-teboroxime. J Nucl Med. 1994;35:923–4.PubMed
7.
go back to reference Pentlow KS, et al. Quantitative imaging of Iodine-124 PET. J Nucl Med. 1996;37:1557–62.PubMed Pentlow KS, et al. Quantitative imaging of Iodine-124 PET. J Nucl Med. 1996;37:1557–62.PubMed
8.
go back to reference Lubberink M, van Schie A, de Jong HWAM, van Dongen GAMS, Teule GJJ. Acquisition settings for PET of 124I dministered simultaneously with therapeutic amounts of 131I. J Nucl Med. 2006;47:1375–81.PubMed Lubberink M, van Schie A, de Jong HWAM, van Dongen GAMS, Teule GJJ. Acquisition settings for PET of 124I dministered simultaneously with therapeutic amounts of 131I. J Nucl Med. 2006;47:1375–81.PubMed
9.
go back to reference Finn R. Chemistry applied to iodine radionuclides. Handbook of radiopharmaceuticals. Chichester: Wiley; 2003. p. 423–5. Finn R. Chemistry applied to iodine radionuclides. Handbook of radiopharmaceuticals. Chichester: Wiley; 2003. p. 423–5.
10.
go back to reference Rault E, Vandenberghe S, Van Holen R, De Beenhouwer J, Staelens S, Lemahieu I. Comparison of image quality of different iodine isotopes (I-123, I-124, and I-131). Cancer Biother Radiopharm. 2007;22:423–30.PubMedCrossRef Rault E, Vandenberghe S, Van Holen R, De Beenhouwer J, Staelens S, Lemahieu I. Comparison of image quality of different iodine isotopes (I-123, I-124, and I-131). Cancer Biother Radiopharm. 2007;22:423–30.PubMedCrossRef
11.
go back to reference Brambilla M, Matheoud R, Secco C, Sacchetti G, Comi S, Rudoni M, et al. Impact of target-to-background ratio, target size, emission scan duration, and activity on physical figures of merit for a 3D LSO-based whole body PET/CT scanner. Med Phys 2007;34:3854–65.PubMedCrossRef Brambilla M, Matheoud R, Secco C, Sacchetti G, Comi S, Rudoni M, et al. Impact of target-to-background ratio, target size, emission scan duration, and activity on physical figures of merit for a 3D LSO-based whole body PET/CT scanner. Med Phys 2007;34:3854–65.PubMedCrossRef
12.
go back to reference Vandenberghe S. Three-dimensional positron emission tomography imaging with 124I and 86Y. Nucl Med Commun. 2006;27:237–45.PubMedCrossRef Vandenberghe S. Three-dimensional positron emission tomography imaging with 124I and 86Y. Nucl Med Commun. 2006;27:237–45.PubMedCrossRef
13.
go back to reference Pentlow KS, Graham MC, Lambrecht RM, Cheung N-KV, Larson SM. Quantitative imaging of I-124 using positron emission tomography with applications to radioimmunodiagnosis and radioimmunotherapy. Med Phys. 1991;18:357–66.PubMedCrossRef Pentlow KS, Graham MC, Lambrecht RM, Cheung N-KV, Larson SM. Quantitative imaging of I-124 using positron emission tomography with applications to radioimmunodiagnosis and radioimmunotherapy. Med Phys. 1991;18:357–66.PubMedCrossRef
14.
go back to reference Pentlow KS, Finn RD, Larson SM, Erdi YE, Beattie BJ, Humm JL. Quantitative imaging of Yttrium-86 with PET—the occurrence and correction of anomalous apparent activity in high density regione. Clin Positron Imaging. 2000;3:85–90.PubMedCrossRef Pentlow KS, Finn RD, Larson SM, Erdi YE, Beattie BJ, Humm JL. Quantitative imaging of Yttrium-86 with PET—the occurrence and correction of anomalous apparent activity in high density regione. Clin Positron Imaging. 2000;3:85–90.PubMedCrossRef
15.
go back to reference Walrand S, Jamar F, Mathieu I, De Camps J, Lonneux M, Sibomana M, et al. Quantitation in PET using isotopes emitting prompt single gammas: application to yttrium-86. Eur J Nucl Med. 2003;30:354–61. Walrand S, Jamar F, Mathieu I, De Camps J, Lonneux M, Sibomana M, et al. Quantitation in PET using isotopes emitting prompt single gammas: application to yttrium-86. Eur J Nucl Med. 2003;30:354–61.
16.
go back to reference Herzog H, Tellmann L, Scholten B, Coenen HH, Qaim SM. PET imaging problems with the non-standard positron emitters Yttrium-86 and Iodine-124. Q J Nucl Med Mol Imaging. 2007;52:159–65.PubMed Herzog H, Tellmann L, Scholten B, Coenen HH, Qaim SM. PET imaging problems with the non-standard positron emitters Yttrium-86 and Iodine-124. Q J Nucl Med Mol Imaging. 2007;52:159–65.PubMed
17.
go back to reference Taylor A Jr, Nally JV. Clinical applications of renal scintigraphy. AJR Am J Roentgenol. 1995;164:31–41.PubMed Taylor A Jr, Nally JV. Clinical applications of renal scintigraphy. AJR Am J Roentgenol. 1995;164:31–41.PubMed
18.
go back to reference Unver T, Alpay H, Biyikli NK, Ones T. Comparison of direct radionuclide cystography and voiding cystourethrography in detecting vesicoureteral reflux. Pediatr Int. 2006;48:287–91. Jun.PubMedCrossRef Unver T, Alpay H, Biyikli NK, Ones T. Comparison of direct radionuclide cystography and voiding cystourethrography in detecting vesicoureteral reflux. Pediatr Int. 2006;48:287–91. Jun.PubMedCrossRef
19.
go back to reference Mariani G, Boni G, Barreca M, Bellini M, Fattori B, AlSharif A, et al. Radionuclide gastro-esophageal motor studies. J Nucl Med. 2004;45:1004–28.PubMed Mariani G, Boni G, Barreca M, Bellini M, Fattori B, AlSharif A, et al. Radionuclide gastro-esophageal motor studies. J Nucl Med. 2004;45:1004–28.PubMed
20.
go back to reference Mariani G, Pauwels EKJ, AlSharif A, Marchi S, Boni G, Barreca M, Bellini M, et al. Radionuclide evaluation of the lower gastrointestinal tract. J Nucl Med. 2008;49:776–87.PubMedCrossRef Mariani G, Pauwels EKJ, AlSharif A, Marchi S, Boni G, Barreca M, Bellini M, et al. Radionuclide evaluation of the lower gastrointestinal tract. J Nucl Med. 2008;49:776–87.PubMedCrossRef
21.
go back to reference Katsuhiro U. Clinical evaluation of hepatobiliary scintigraphy. Japan J Med Imaging. 1999;18:111–22. Katsuhiro U. Clinical evaluation of hepatobiliary scintigraphy. Japan J Med Imaging. 1999;18:111–22.
22.
go back to reference Shah KK, Shah KK, Fink-Bennett D, Kumar KG, McCaughey RS. Extrahepatic biliary obstruction versus intrahepatic disorder. Differentiation with hepatobiliary scintigraphy and ultrasonography. J Clin Gastroenterol. 1988;10:191–6.PubMedCrossRef Shah KK, Shah KK, Fink-Bennett D, Kumar KG, McCaughey RS. Extrahepatic biliary obstruction versus intrahepatic disorder. Differentiation with hepatobiliary scintigraphy and ultrasonography. J Clin Gastroenterol. 1988;10:191–6.PubMedCrossRef
23.
go back to reference Connolly LP, Treves ST, Bozorgi F, O’Connor SC. Meckel’s diverticulum: demonstration of heterotopic gastric mucosa with technetium-99m-pertechnetate SPECT. J Nucl Med. 1998;39:1458–60.PubMed Connolly LP, Treves ST, Bozorgi F, O’Connor SC. Meckel’s diverticulum: demonstration of heterotopic gastric mucosa with technetium-99m-pertechnetate SPECT. J Nucl Med. 1998;39:1458–60.PubMed
24.
go back to reference Schillaci O, Filippi L, Danieli R, Simonetti G. Single-photon emission computed tomography/computed tomography in abdominal diseases. Semin Nucl Med. 2007;37:48–61.PubMedCrossRef Schillaci O, Filippi L, Danieli R, Simonetti G. Single-photon emission computed tomography/computed tomography in abdominal diseases. Semin Nucl Med. 2007;37:48–61.PubMedCrossRef
25.
go back to reference Weissleder H, Weissleder R. Lymphedema: evaluation of qualitative and quantitative lymphoscintigraphy in 238 patients. Radiology. 1988;167:729–35.PubMed Weissleder H, Weissleder R. Lymphedema: evaluation of qualitative and quantitative lymphoscintigraphy in 238 patients. Radiology. 1988;167:729–35.PubMed
26.
go back to reference Vaqueiro M, Gloviczki P, Fisher J, Hollier LH, A Schirger A, Wahner HW. Lymphoscintigraphy in lymphedema: an aid to microsurgery. J Nucl Med. 1986;27:1125–30.PubMed Vaqueiro M, Gloviczki P, Fisher J, Hollier LH, A Schirger A, Wahner HW. Lymphoscintigraphy in lymphedema: an aid to microsurgery. J Nucl Med. 1986;27:1125–30.PubMed
27.
go back to reference Mariani G, Moresco L, Viale G, Villa G, Bagnasco M, Canavese G, et al. Radioguided sentinel lymph node biopsy in breast cancer surgery. J Nucl Med. 2001;42:1198–15.PubMed Mariani G, Moresco L, Viale G, Villa G, Bagnasco M, Canavese G, et al. Radioguided sentinel lymph node biopsy in breast cancer surgery. J Nucl Med. 2001;42:1198–15.PubMed
28.
go back to reference Mariani G, Gipponi M, Moresco L, Villa G, Bartolomei M, Mazzarol G, et al. Radioguided sentinel lymph node biopsy in malignant cutaneous melanoma. J Nucl Med. 2002;43:811–27.PubMed Mariani G, Gipponi M, Moresco L, Villa G, Bartolomei M, Mazzarol G, et al. Radioguided sentinel lymph node biopsy in malignant cutaneous melanoma. J Nucl Med. 2002;43:811–27.PubMed
29.
go back to reference Mariani G, Giuliano AE, Strauss HW. Radioguided surgery: a comprehensive team approach. New York, NY: Springer; 2008. Mariani G, Giuliano AE, Strauss HW. Radioguided surgery: a comprehensive team approach. New York, NY: Springer; 2008.
30.
go back to reference Bajc M, Albrechtsson U, Olsson C-G, Olsson B, Jonson B. Comparison of ventilation/perfusion scintigraphy and helical CT for diagnosis of pulmonary embolism; strategy using clinical data and ancillary findings. Clin Physiol Funct Imaging. 2002;22:392–7.PubMedCrossRef Bajc M, Albrechtsson U, Olsson C-G, Olsson B, Jonson B. Comparison of ventilation/perfusion scintigraphy and helical CT for diagnosis of pulmonary embolism; strategy using clinical data and ancillary findings. Clin Physiol Funct Imaging. 2002;22:392–7.PubMedCrossRef
31.
go back to reference Stein PD, Woodard PK, Weg JG, Wakefield TW, Tapson VF, Sostman HD, et al. Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II investigators. Radiology. 2007;242:15–21.PubMedCrossRef Stein PD, Woodard PK, Weg JG, Wakefield TW, Tapson VF, Sostman HD, et al. Diagnostic pathways in acute pulmonary embolism: recommendations of the PIOPED II investigators. Radiology. 2007;242:15–21.PubMedCrossRef
32.
go back to reference Forstrom LA, Mullan BP, Hung JC, Lowe VJ, Thorson LM. 18F-FDG labelling of human leukocytes. Nucl Med Commun. 2000;21:691–4.PubMed Forstrom LA, Mullan BP, Hung JC, Lowe VJ, Thorson LM. 18F-FDG labelling of human leukocytes. Nucl Med Commun. 2000;21:691–4.PubMed
33.
go back to reference Osman S, Danpure HJ. The use of 2-[18F]-fluoro-2-deoxy-d-glucose as a potential in vitro agent for labelling human granulocytes for clinical studies by positron emission tomography. Int J Rad Appl Instrum B. 1992;19:183–90.PubMed Osman S, Danpure HJ. The use of 2-[18F]-fluoro-2-deoxy-d-glucose as a potential in vitro agent for labelling human granulocytes for clinical studies by positron emission tomography. Int J Rad Appl Instrum B. 1992;19:183–90.PubMed
34.
go back to reference Guhlmann A, Brecht-Krauss D, Suger G, Glatting G, Kotzerke J, Kinzl L, et al. Chronic osteomyelitis: detection with FDG PET and correlation with histopathologic findings. Radiology. 1998;206:749–54.PubMed Guhlmann A, Brecht-Krauss D, Suger G, Glatting G, Kotzerke J, Kinzl L, et al. Chronic osteomyelitis: detection with FDG PET and correlation with histopathologic findings. Radiology. 1998;206:749–54.PubMed
35.
go back to reference Stumpe KDM, Zanetti M, Weishaupt D, Hodler J, Boos N, von Schulthess GK. FDG positron emission tomography for differentiation of degenerative and infectious endplate abnormalities in the lumbar spine detected on MR imaging. AJR Am J Roentgenol. 2002;179:1151–7.PubMed Stumpe KDM, Zanetti M, Weishaupt D, Hodler J, Boos N, von Schulthess GK. FDG positron emission tomography for differentiation of degenerative and infectious endplate abnormalities in the lumbar spine detected on MR imaging. AJR Am J Roentgenol. 2002;179:1151–7.PubMed
36.
go back to reference Gratz S, Dorner J, Fischer U, Behr TM, Behe M, Altenvoerde G, Meller J, et al. 18F-FDG hybrid PET in patients with suspected spondylitis. Eur J Nucl Med Mol Imaging. 2002;29:516–24.PubMedCrossRef Gratz S, Dorner J, Fischer U, Behr TM, Behe M, Altenvoerde G, Meller J, et al. 18F-FDG hybrid PET in patients with suspected spondylitis. Eur J Nucl Med Mol Imaging. 2002;29:516–24.PubMedCrossRef
37.
go back to reference De Winter F, Gemmel F, Van de Wiele C, Poffijn B, Uyttendaele D, Dierckx R. 18-Fluorine fluorodeoxyglucose positron emission tomography for the diagnosis of infection in the postoperative spine. Spine. 2003;28:1314–9.PubMedCrossRef De Winter F, Gemmel F, Van de Wiele C, Poffijn B, Uyttendaele D, Dierckx R. 18-Fluorine fluorodeoxyglucose positron emission tomography for the diagnosis of infection in the postoperative spine. Spine. 2003;28:1314–9.PubMedCrossRef
38.
go back to reference O’Connor MK, Kemp BJ. Single-photon emission computed tomography/computed tomography: basic instrumentation and innovations. Semin Nucl Med. 2006;36:258–66.PubMedCrossRef O’Connor MK, Kemp BJ. Single-photon emission computed tomography/computed tomography: basic instrumentation and innovations. Semin Nucl Med. 2006;36:258–66.PubMedCrossRef
39.
go back to reference Beekman F, Hutton B. Multi-modality imaging on track. Eur J Nucl Med Mol Imaging. 2007;34:1410–4.PubMedCrossRef Beekman F, Hutton B. Multi-modality imaging on track. Eur J Nucl Med Mol Imaging. 2007;34:1410–4.PubMedCrossRef
40.
go back to reference Husarik DB, Steinert HC. Single-photon emission computed tomography/computed tomography for sentinel node mapping in breast cancer. Semin Nucl Med. 2007;37:29–33.PubMedCrossRef Husarik DB, Steinert HC. Single-photon emission computed tomography/computed tomography for sentinel node mapping in breast cancer. Semin Nucl Med. 2007;37:29–33.PubMedCrossRef
41.
go back to reference Krausz Y, Israel O. Single-photon emission computed tomography/computed tomography in endocrinology. Semin Nucl Med. 2006;36:267–74.PubMedCrossRef Krausz Y, Israel O. Single-photon emission computed tomography/computed tomography in endocrinology. Semin Nucl Med. 2006;36:267–74.PubMedCrossRef
42.
go back to reference Schillaci O. Single-photon emission computed tomography/computed tomography in lung cancer and malignant lymphoma. Semin Nucl Med. 2006;36:275–85.PubMedCrossRef Schillaci O. Single-photon emission computed tomography/computed tomography in lung cancer and malignant lymphoma. Semin Nucl Med. 2006;36:275–85.PubMedCrossRef
43.
go back to reference Horger M, Bares R. The role of single-photon emission computed tomography/computed tomography in benign and malignant bone disease. Semin Nucl Med. 2006;36:286–94.PubMedCrossRef Horger M, Bares R. The role of single-photon emission computed tomography/computed tomography in benign and malignant bone disease. Semin Nucl Med. 2006;36:286–94.PubMedCrossRef
44.
go back to reference Bunyaviroch T, Aggarwal A, Oates ME. Optimized scintigraphic evaluation of infection and inflammation: role of single-photon emission computed tomography/computed tomography fusion imaging. Semin Nucl Med. 2006;36:295–311.PubMedCrossRef Bunyaviroch T, Aggarwal A, Oates ME. Optimized scintigraphic evaluation of infection and inflammation: role of single-photon emission computed tomography/computed tomography fusion imaging. Semin Nucl Med. 2006;36:295–311.PubMedCrossRef
45.
go back to reference Sodee DB, Sodee AE, Bakale G. Synergistic value of single-photon emission computed tomography/computed tomography fusion to radioimmunoscintigraphic imaging of prostate cancer. Semin Nucl Med. 2007;37:17–28.PubMedCrossRef Sodee DB, Sodee AE, Bakale G. Synergistic value of single-photon emission computed tomography/computed tomography fusion to radioimmunoscintigraphic imaging of prostate cancer. Semin Nucl Med. 2007;37:17–28.PubMedCrossRef
46.
go back to reference Schillaci O, Filippi L, Manni C, Santoni R. Single-photon emission computed tomography/computed tomography in brain tumors. Semin Nucl Med. 2007;37:34–47.PubMedCrossRef Schillaci O, Filippi L, Manni C, Santoni R. Single-photon emission computed tomography/computed tomography in brain tumors. Semin Nucl Med. 2007;37:34–47.PubMedCrossRef
47.
go back to reference Lee ST, Scott AM. Hypoxia positron emission tomography imaging with 18F-fluoromisonidazole. Semin Nucl Med. 2007;37:451–61.PubMedCrossRef Lee ST, Scott AM. Hypoxia positron emission tomography imaging with 18F-fluoromisonidazole. Semin Nucl Med. 2007;37:451–61.PubMedCrossRef
48.
go back to reference Kelly CJ, Brady M. A model to simulate tumour oxygenation and dynamic [18F]-Fmiso PET data. Phys Med Biol. 2006;51:5859–73.PubMedCrossRef Kelly CJ, Brady M. A model to simulate tumour oxygenation and dynamic [18F]-Fmiso PET data. Phys Med Biol. 2006;51:5859–73.PubMedCrossRef
49.
go back to reference Padhani AR, Krohn KA, Lewis JS, Alber M. Imaging oxygenation of human tumours. Eur Radiol. 2007;17:861–72.PubMedCrossRef Padhani AR, Krohn KA, Lewis JS, Alber M. Imaging oxygenation of human tumours. Eur Radiol. 2007;17:861–72.PubMedCrossRef
50.
go back to reference Halley A, Hugentobler A, Icard P, Porret E, Sobrio F, Lerochais JP, et al. Efficiency of 18F-FDG and 99mTc-depreotide SPECT in the diagnosis of malignancy of solitary pulmonary nodules. Eur J Nucl Med Mol Imaging. 2005;32:1026–32.PubMedCrossRef Halley A, Hugentobler A, Icard P, Porret E, Sobrio F, Lerochais JP, et al. Efficiency of 18F-FDG and 99mTc-depreotide SPECT in the diagnosis of malignancy of solitary pulmonary nodules. Eur J Nucl Med Mol Imaging. 2005;32:1026–32.PubMedCrossRef
51.
go back to reference Rodrigues M, Li S, Gabriel M, Heute D, Greifeneder M, Virgolini I. 99mTc-depreotide scintigraphy versus 18F-FDG-PET in the diagnosis of radioiodine-negative thyroid cancer. J Clin Endocrinol Metab. 2006;91:3997–4000.PubMedCrossRef Rodrigues M, Li S, Gabriel M, Heute D, Greifeneder M, Virgolini I. 99mTc-depreotide scintigraphy versus 18F-FDG-PET in the diagnosis of radioiodine-negative thyroid cancer. J Clin Endocrinol Metab. 2006;91:3997–4000.PubMedCrossRef
52.
go back to reference Mariani G, Gulec SA, Rubello D, Boni G, Puccini M, Pelizzo MR, et al. Preoperative localization and radioguided parathyroid surgery. J Nucl Med 2003;44:1443–58.PubMed Mariani G, Gulec SA, Rubello D, Boni G, Puccini M, Pelizzo MR, et al. Preoperative localization and radioguided parathyroid surgery. J Nucl Med 2003;44:1443–58.PubMed
53.
go back to reference Rahmim A, Zaidi H. PET versus SPECT: strengths, limitations and challenges. Nucl Med Commun. 2008;29:193–207.PubMedCrossRef Rahmim A, Zaidi H. PET versus SPECT: strengths, limitations and challenges. Nucl Med Commun. 2008;29:193–207.PubMedCrossRef
Metadata
Title
Is PET always an advantage versus planar and SPECT imaging?
Authors
Giuliano Mariani
Laura Bruselli
Adriano Duatti
Publication date
01-08-2008
Publisher
Springer-Verlag
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue 8/2008
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-008-0814-1

Other articles of this Issue 8/2008

European Journal of Nuclear Medicine and Molecular Imaging 8/2008 Go to the issue