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Published in: European Journal of Nuclear Medicine and Molecular Imaging 1/2007

01-01-2007 | Image of the month

MIBG-SPECT/CT-angiography with 3-D reconstruction of an extra-adrenal phaeochromocytoma with dissection of an aortic aneurysm

Authors: Klaus Strobel, C. Burger, P. Schneider, M. Weber, Thomas F. Hany

Published in: European Journal of Nuclear Medicine and Molecular Imaging | Issue 1/2007

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Excerpt

Phaeochromocytomas can cause severe complications like stroke, lung oedema, myocardial infarction or aortic dissection. Ten percent of phaeochromocytomas originate in extra-adrenal localisations and can be detected with 123I-MIBG scintigraphy [1]. We report on a 50-year-old patient with weight loss, night sweating and increased urinary noradrenaline levels. SPECT with 358 MBq 123I-MIBG and additionally a dual-phase diagnostic CT were performed, showing increased MIBG uptake para-aortally on the left side (a,b, arrow) corresponding to a hypervascularised lesion visible on CT (b, arrow) [2]. Additionally, in CT a thoracic aneurysm with type B aortic dissection (a,b, arrowheads) was detected. For surgical planning, CT-angiography and SPECT were combined in a fused 3D rendering using the PMOD 2.75 software (see figure). The paraganglioma was resected and 1 month later the aneurysm was successfully treated with a stent graft. There are some case reports in the literature about phaeochromocytomas associated with aortic or carotid dissections [35]. SPECT/CT-angiography with fused 3D reconstruction requires appropriate software and some postprocessing time but provides the surgeon with important functional and morphological information for adequate therapy planning. 18F-DOPA PET/CT could be another interesting tool for imaging of such patients [6].
https://static-content.springer.com/image/art%3A10.1007%2Fs00259-006-0240-1/MediaObjects/259_2006_240_Figa_HTML.jpg
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Metadata
Title
MIBG-SPECT/CT-angiography with 3-D reconstruction of an extra-adrenal phaeochromocytoma with dissection of an aortic aneurysm
Authors
Klaus Strobel
C. Burger
P. Schneider
M. Weber
Thomas F. Hany
Publication date
01-01-2007
Publisher
Springer-Verlag
Published in
European Journal of Nuclear Medicine and Molecular Imaging / Issue 1/2007
Print ISSN: 1619-7070
Electronic ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-006-0240-1

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