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Published in: Skeletal Radiology 11/2017

01-11-2017 | Case Report

Radiation-induced focal cortical necrosis of the femur presenting as a lytic lesion

Authors: Hakan Ilaslan, Jean Schils, Michael Joyce, Chirag Shah, Yaxia Zhang

Published in: Skeletal Radiology | Issue 11/2017

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Abstract

Management of soft tissue sarcomas is often complicated, requiring radiation before and in some cases after limb-sparing surgery. Radiation necrosis is a severe complication after radiation treatment and is typically dose related and involves medullary bone. We report on two cases of hitherto unreported focal circumscribed intra-cortical lytic lesions within the radiation portal, which appeared 19 months and 31 months, respectively, after the conclusion of radiation treatment. Both patients had a history of soft tissue sarcoma treated with radiation (66 Gy) and surgical resection. Biopsy of these lesions showed necrotic bone attributed to radiation.
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Metadata
Title
Radiation-induced focal cortical necrosis of the femur presenting as a lytic lesion
Authors
Hakan Ilaslan
Jean Schils
Michael Joyce
Chirag Shah
Yaxia Zhang
Publication date
01-11-2017
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 11/2017
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-017-2715-5

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