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Skeletal Radiology
Published in: Skeletal Radiology 5/2016

01-05-2016 | Scientific Article

Three-dimensional volumetric MRI with isotropic resolution: improved speed of acquisition, spatial resolution and assessment of lesion conspicuity in patients with recurrent soft tissue sarcoma

Authors: Shivani Ahlawat, Carol Morris, Laura M. Fayad

Published in: Skeletal Radiology | Issue 5/2016

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Abstract

Background

To assess the acquisition speed, lesion conspicuity, and inter-observer agreement associated with volumetric T1-weighted MR sequences with isotropic resolution for detecting recurrent soft-tissue sarcoma (STS).

Methods

Fifteen subjects with histologically proven recurrent STS underwent MRI, including axial and coronal T1-weighted spin echo (T1-WSE) (5-mm slice thickness) and coronal 3D volumetric T1-weighted (fat-suppressed, volume-interpolated, breath-hold examination; repetition time/echo time, 3.7/1.4 ms; flip angle, 9.5°; 1-mm slice thickness) sequences before and after intravenous contrast administration. Subtraction imaging and multiplanar reformations (MPRs) were performed. Acquisition times for T1-WSE in two planes and 3D sequences were reported. Two radiologists reviewed images for quality (>50 % artifacts, 25–50 % artifacts, <25 % artifacts, and no substantial artifacts), lesion conspicuity, contrast-to-noise ratio (CNRmuscle), recurrence size, and recurrence-to-joint distance. Descriptive and intraclass correlation (ICC) statistics are given.

Results

Mean acquisition times were significantly less for 3D imaging compared with 2-plane T1-WSE (183.6 vs 342.6 s; P = 0.012). Image quality was rated as having no substantial artifacts in 13/15 and <25 % artifacts in 2/15. Lesion conspicuity was significantly improved for subtracted versus unsubtracted images (CNRmuscle, 100 ± 138 vs 181 ± 199; P = 0.05). Mean recurrent lesion size was 2.5 cm (range, 0.7–5.7 cm), and measurements on 3D sequences offered excellent interobserver agreement (ICC, 0.98 for lesion size and 0.96 for recurrence-to-joint distance with MPR views).

Conclusion

Three-dimensional volumetric sequences offer faster acquisition times, higher spatial resolution, and MPR capability compared with 2D T1-WSE for postcontrast imaging. Subtraction imaging provides higher lesion conspicuity for detecting recurrent STS in skeletal muscle, with excellent interobserver agreement between readers.
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Metadata
Title
Three-dimensional volumetric MRI with isotropic resolution: improved speed of acquisition, spatial resolution and assessment of lesion conspicuity in patients with recurrent soft tissue sarcoma
Authors
Shivani Ahlawat
Carol Morris
Laura M. Fayad
Publication date
01-05-2016
Publisher
Springer Berlin Heidelberg
Published in
Skeletal Radiology / Issue 5/2016
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-016-2348-0

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