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Published in: Skeletal Radiology 10/2007

01-10-2007 | Perspective

Mesenchymal stem and progenitor cells for cartilage repair

Authors: Nazish Ahmed, William L. Stanford, Rita A. Kandel

Published in: Skeletal Radiology | Issue 10/2007

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Excerpt

Treatment of damaged articular cartilage is problematic due in part to the avascularity of the tissue. Regenerative medicine and tissue engineering offer new approaches for the repair or replacement of damaged or diseased tissue. There is now proof-of-concept to support cell-based regeneration of cartilage, but one of the major issues limiting its use clinically is the availability of a cell source that will form sufficient amounts of tissue comparable to in vivo cartilage both in composition and in mechanical properties. One possible option is to use stem and progenitor cells. This perspective will describe the promise and limitations of the use of stem cells for cartilage repair. …
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Metadata
Title
Mesenchymal stem and progenitor cells for cartilage repair
Authors
Nazish Ahmed
William L. Stanford
Rita A. Kandel
Publication date
01-10-2007
Publisher
Springer-Verlag
Published in
Skeletal Radiology / Issue 10/2007
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI
https://doi.org/10.1007/s00256-007-0333-3

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