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01-06-2007 | Case Report

Solitary myofibroma of the lumbar vertebra: adult case

Authors: E. Konishi, T. Mazaki, Y. Urata, K. Tanaka, H. Kanoe, M. Ikenaga, K. Hayakawa, A. Yanagisawa

Published in: Skeletal Radiology | Special Issue 1/2007

Abstract

We present the first known adult case of solitary myofibroma of bone, which affected a lumbar vertebra in a 33-year-old male. Radiography identified a purely lytic lesion with a sclerotic rim in the right pedicle of L1. CT showed an expansile lytic lesion with a sclerotic rim. MRI of the lesion revealed an isointense signal on T1-weighted images, an inhomogeneously hyperintense signal on T2-weighted images, and marked enhancement with gadolinium. Pathological study showed a mixed picture of nodular proliferation of spindle-shaped myoid cells and hemangiopericytomatous proliferation of short spindle/small round cells. The tumor cells were immunoreactive for smooth muscle actin and immunonegative for desmin. This case of solitary myofibroma of bone is exceptionally rare because of its occurrence in an adult older than 20 years of age and its location at an extra-craniofacial site.

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Title: Solitary myofibroma of the lumbar vertebra: adult case
Authors: E. Konishi
T. Mazaki
Y. Urata
K. Tanaka
H. Kanoe
M. Ikenaga
K. Hayakawa
A. Yanagisawa
Publication date: 01-06-2007
Publisher: Springer Berlin Heidelberg
Published in: Skeletal Radiology / Issue Special Issue 1/2007
Print ISSN: 0364-2348
Electronic ISSN: 1432-2161
DOI: https://doi.org/10.1007/s00256-006-0132-2

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Solitary myofibroma of the lumbar vertebra: adult case

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