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Published in: Pediatric Radiology 8/2021

Open Access 01-07-2021 | Pleural Effusion | Original Article

Training physicians in India to interpret pediatric chest radiographs according to World Health Organization research methodology

Authors: Eric D. McCollum, Melissa M. Higdon, Nicholas S. S. Fancourt, Jack Sternal, William Checkley, John De Campo, Anita Shet

Published in: Pediatric Radiology | Issue 8/2021

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Abstract

Background

Chest radiography is the standard for diagnosing pediatric lower respiratory infections in low-income and middle-income countries. A method for interpreting pediatric chest radiographs for research endpoints was recently updated by the World Health Organization (WHO) Chest Radiography in Epidemiological Studies project. Research in India required training local physicians to interpret chest radiographs following the WHO method.

Objective

To describe the methodology for training Indian physicians and evaluate the training’s effectiveness.

Materials and methods

Twenty-nine physicians (15 radiologists and 14 pediatricians) from India were trained by two WHO Chest Radiography in Epidemiological Studies members over 3 days in May 2019. Training materials were adapted from WHO Chest Radiography in Epidemiological Studies resources. Participants followed WHO methodology to interpret 60 unique chest radiographs before and after the training. Participants needed to correctly classify ≥80% of radiographs for primary endpoint pneumonia on the post-training test to be certified to interpret research images. We analyzed participant performance on both examinations.

Results

Twenty-six of 29 participants (89.7%) completed both examinations. The average score increased by 9.6% (95% confidence interval [CI] 5.0–14.1%) between examinations (P<0.001). Participants correctly classifying ≥80% of images for primary endpoint pneumonia increased from 69.2% (18/26) on the pretraining to 92.3% (24/26) on the post-training examination (P=0.003). The mean scores of radiologists and pediatricians on the post-training examination were not statistically different (P=0.43).

Conclusion

Our results demonstrate this training approach using revised WHO definitions and tools was successful, and that non-radiologists can learn to apply these methods as effectively as radiologists. Such capacity strengthening is important for enabling research to support national policy decision-making in these settings. We recommend future research incorporating WHO chest radiograph methodology to consider modelling trainings after this approach.
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Literature
1.
go back to reference GBD (2017) Lower respiratory infections collaborators (2020) quantifying risks and interventions that have affected the burden of lower respiratory infections among children younger than 5 years: an analysis for the global burden of disease study 2017. Lancet Infect Dis 20:60–79 GBD (2017) Lower respiratory infections collaborators (2020) quantifying risks and interventions that have affected the burden of lower respiratory infections among children younger than 5 years: an analysis for the global burden of disease study 2017. Lancet Infect Dis 20:60–79
2.
go back to reference Liu L, Chu Y, Oza S et al (2019) National, regional, and state-level all-cause and cause-specific under-5 mortality in India in 2000-15: a systematic analysis with implications for the sustainable development goals. Lancet Glob Health 7:e721–e734CrossRef Liu L, Chu Y, Oza S et al (2019) National, regional, and state-level all-cause and cause-specific under-5 mortality in India in 2000-15: a systematic analysis with implications for the sustainable development goals. Lancet Glob Health 7:e721–e734CrossRef
3.
go back to reference Wahl B, O'Brien KL, Greenbaum A et al (2018) Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000-15. Lancet Glob Health 6:e744–e757CrossRef Wahl B, O'Brien KL, Greenbaum A et al (2018) Burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in the era of conjugate vaccines: global, regional, and national estimates for 2000-15. Lancet Glob Health 6:e744–e757CrossRef
4.
go back to reference Wahl B, Sharan A, Deloria Knoll M et al (2018) National, regional, and state-level burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in India: modelled estimates for 2000-15. Lancet Glob Health 7:e735–e747CrossRef Wahl B, Sharan A, Deloria Knoll M et al (2018) National, regional, and state-level burden of Streptococcus pneumoniae and Haemophilus influenzae type b disease in children in India: modelled estimates for 2000-15. Lancet Glob Health 7:e735–e747CrossRef
7.
go back to reference Pneumonia Etiology Research for Child Health (PERCH) Study Group (2019) Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study. Lancet 394:757–779CrossRef Pneumonia Etiology Research for Child Health (PERCH) Study Group (2019) Causes of severe pneumonia requiring hospital admission in children without HIV infection from Africa and Asia: the PERCH multi-country case-control study. Lancet 394:757–779CrossRef
8.
go back to reference Cherian T, Mulholland EK, Carlin JB et al (2005) Standardized interpretation of paediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies. Bull World Health Organ 83:353–359PubMedPubMedCentral Cherian T, Mulholland EK, Carlin JB et al (2005) Standardized interpretation of paediatric chest radiographs for the diagnosis of pneumonia in epidemiological studies. Bull World Health Organ 83:353–359PubMedPubMedCentral
9.
go back to reference Mackenzie GA, Hill PC, Sahito SM et al (2017) Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in the Gambia: population-based surveillance and case-control studies. Lancet Infect Dis 17:965–973CrossRef Mackenzie GA, Hill PC, Sahito SM et al (2017) Impact of the introduction of pneumococcal conjugate vaccination on pneumonia in the Gambia: population-based surveillance and case-control studies. Lancet Infect Dis 17:965–973CrossRef
10.
go back to reference McCollum ED, Ahmed S, Chowdhury NH et al (2019) Chest radiograph reading panel performance in a Bangladesh pneumococcal vaccine effectiveness study. BMJ Open Respir Res 6:e000393CrossRef McCollum ED, Ahmed S, Chowdhury NH et al (2019) Chest radiograph reading panel performance in a Bangladesh pneumococcal vaccine effectiveness study. BMJ Open Respir Res 6:e000393CrossRef
11.
go back to reference Klugman KP, Madhi SA, Huebner RE et al (2003) A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection. N Engl J Med 349:1341–1348CrossRef Klugman KP, Madhi SA, Huebner RE et al (2003) A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection. N Engl J Med 349:1341–1348CrossRef
12.
go back to reference Madhi SA, Groome MJ, Zar HJ et al (2015) Effectiveness of pneumococcal conjugate vaccine against presumed bacterial pneumonia hospitalisation in HIV-uninfected south African children: a case-control study. Thorax 70:1149–1155CrossRef Madhi SA, Groome MJ, Zar HJ et al (2015) Effectiveness of pneumococcal conjugate vaccine against presumed bacterial pneumonia hospitalisation in HIV-uninfected south African children: a case-control study. Thorax 70:1149–1155CrossRef
13.
go back to reference Lucero MG, Nohynek H, Williams G et al (2009) Efficacy of an 11-valent pneumococcal conjugate vaccine against radiologically confirmed pneumonia among children less than 2 years of age in the Philippines: a randomized, double-blind, placebo-controlled trial. Pediatr Infect Dis J 28:455–462CrossRef Lucero MG, Nohynek H, Williams G et al (2009) Efficacy of an 11-valent pneumococcal conjugate vaccine against radiologically confirmed pneumonia among children less than 2 years of age in the Philippines: a randomized, double-blind, placebo-controlled trial. Pediatr Infect Dis J 28:455–462CrossRef
14.
go back to reference Cutts FT, Zaman SMA, Enwere G et al (2005) Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in the Gambia: randomised, double-blind, placebo-controlled trial. Lancet 365:1139–1146CrossRef Cutts FT, Zaman SMA, Enwere G et al (2005) Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in the Gambia: randomised, double-blind, placebo-controlled trial. Lancet 365:1139–1146CrossRef
16.
go back to reference Baqui AH, El Arifeen S, Saha SK et al (2007) Effectiveness of Haemophilus influenzae type B conjugate vaccine on prevention of pneumonia and meningitis in Bangladeshi children: a case-control study. Pediatr Infect Dis J 26:565–571CrossRef Baqui AH, El Arifeen S, Saha SK et al (2007) Effectiveness of Haemophilus influenzae type B conjugate vaccine on prevention of pneumonia and meningitis in Bangladeshi children: a case-control study. Pediatr Infect Dis J 26:565–571CrossRef
17.
go back to reference Mahomed N, Fancourt N, de Campo J et al (2017) Preliminary report from the World Health Organisation chest radiography in epidemiological studies project. Pediatr Radiol 47:1399–1404CrossRef Mahomed N, Fancourt N, de Campo J et al (2017) Preliminary report from the World Health Organisation chest radiography in epidemiological studies project. Pediatr Radiol 47:1399–1404CrossRef
18.
go back to reference Clasen T, Checkley W, Peel JL et al (2020) Design and rationale of the HAPIN study: a multicountry randomized controlled trial to assess the effect of liquefied petroleum gas stove and continuous fuel distribution. Environ Health Perspect 128:47008CrossRef Clasen T, Checkley W, Peel JL et al (2020) Design and rationale of the HAPIN study: a multicountry randomized controlled trial to assess the effect of liquefied petroleum gas stove and continuous fuel distribution. Environ Health Perspect 128:47008CrossRef
19.
go back to reference Simkovich SM, Underhill LJ, Kirby MA et al (2020) Design and conduct of facility-based surveillance for severe childhood pneumonia in the household air pollution intervention network (HAPIN) trial. ERJ Open Res 6:00308–02019CrossRef Simkovich SM, Underhill LJ, Kirby MA et al (2020) Design and conduct of facility-based surveillance for severe childhood pneumonia in the household air pollution intervention network (HAPIN) trial. ERJ Open Res 6:00308–02019CrossRef
20.
go back to reference Fancourt N, Deloria Knoll M, Barger-Kamate B et al (2017) Standardized interpretation of chest radiographs in cases of pediatric pneumonia from the PERCH study. Clin Infect Dis 64:S253–S261CrossRef Fancourt N, Deloria Knoll M, Barger-Kamate B et al (2017) Standardized interpretation of chest radiographs in cases of pediatric pneumonia from the PERCH study. Clin Infect Dis 64:S253–S261CrossRef
21.
go back to reference Pervaiz F, Hossen S, Chavez MA et al (2019) Training and standardization of general practitioners in the use of lung ultrasound for the diagnosis of pediatric pneumonia. Pediatr Pulmonol 54:1753–1759CrossRef Pervaiz F, Hossen S, Chavez MA et al (2019) Training and standardization of general practitioners in the use of lung ultrasound for the diagnosis of pediatric pneumonia. Pediatr Pulmonol 54:1753–1759CrossRef
Metadata
Title
Training physicians in India to interpret pediatric chest radiographs according to World Health Organization research methodology
Authors
Eric D. McCollum
Melissa M. Higdon
Nicholas S. S. Fancourt
Jack Sternal
William Checkley
John De Campo
Anita Shet
Publication date
01-07-2021
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 8/2021
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-021-04992-2

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