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Published in: Pediatric Radiology 9/2019

01-08-2019 | Ultrasound | Original Article

Magnetic-resonance-guided focused ultrasound treatment of non-spinal osteoid osteoma in children: multicentre experience

Authors: Francesco Arrigoni, Alessandro Napoli, Alberto Bazzocchi, Luigi Zugaro, Roberto Scipione, Federico Bruno, Pierpaolo Palumbo, Michele Anzidei, Daniele Mercatelli, Giovanni Luca Gravina, Carmine Zoccali, Pejman Ghanouni, Antonio Barile, Carlo Catalano, Carlo Masciocchi

Published in: Pediatric Radiology | Issue 9/2019

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Abstract

Background

Osteoid osteoma is a benign and painful musculoskeletal tumour that usually affects children. Current standard treatment is CT-guided radiofrequency ablation, a minimally invasive percutaneous procedure, with clinical success rates ranging between 85% and 98%. Though minimally invasive, however, this type of procedure is not free from complications.

Objective

To investigate the efficacy and safety of magnetic resonance (MR)-guided focused ultrasound (MRgFUS), a needleless procedure of thermal ablation employed in the treatment of non-spinal osteoid osteoma in paediatric patients.

Materials and methods

We report the results of 33 procedures of ablation of osteoid osteoma performed with MRgFUS in three university hospitals. To ablate a lesion on the bone surface, MRgFUS employs the ultrasound energy transduced along the soft tissue. The follow-up studies lasted 24 months and were performed combining clinical and imaging data.

Results

Mean age of the children was 13.8 years. The clinical outcome showed a primary success of 97%. One case alone was submitted to repeat treatment because the first one failed (secondary success). No major or minor complications were recorded. During the investigation time, no relapse of symptomatology or delayed complications were observed.

Conclusion

Although our study is preliminary and limited by a low number of patients, our data show that MRgFUS is effective. This suggests that it might be useful as the first-line treatment in paediatric patients with osteoid osteoma.
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Metadata
Title
Magnetic-resonance-guided focused ultrasound treatment of non-spinal osteoid osteoma in children: multicentre experience
Authors
Francesco Arrigoni
Alessandro Napoli
Alberto Bazzocchi
Luigi Zugaro
Roberto Scipione
Federico Bruno
Pierpaolo Palumbo
Michele Anzidei
Daniele Mercatelli
Giovanni Luca Gravina
Carmine Zoccali
Pejman Ghanouni
Antonio Barile
Carlo Catalano
Carlo Masciocchi
Publication date
01-08-2019
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 9/2019
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-019-04426-0

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