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Pediatric Radiology

Published in:

01-03-2019 | Original Article

Functional magnetic resonance urography in infants: feasibility of a feed-and-sleep technique

Authors: Ilias Tsiflikas, Florian Obermayr, Sebastian Werner, Matthias Teufel, Jörg Fuchs, Jürgen F. Schäfer

Published in: Pediatric Radiology | Issue 3/2019

Abstract

Background

Functional magnetic resonance (MR) urography has been well established in the diagnostic workup of congenital anomalies of kidneys and urinary tract, though long acquisition time requires sedation or general anesthesia in infants.

Objective

To evaluate the success rate of an optimized functional MR urography protocol in infants carried out in natural sleep.

Materials and methods

We retrospectively evaluated all functional MR urographies performed under general anesthesia or during natural sleep in infants younger than 1 year between 2010 and 2017 and rated image quality in both cohorts using a 3-point Likert scale. We tested the analyzability of functional sequences using a free available software. We also calculated examination time. Finally, we compared examinations in natural sleep and those with general anesthesia using independent t-test for continuous data and Mann–Whitney U test for categorical data.

Results

Functional MR urography could be performed successfully during natural sleep in 38 of 42 (90%) infants younger than 10 months. Four examinations were aborted before contrast medium was administrated. In the same period, 19 functional MR urographies were performed successfully under general anesthesia. Although image quality was significantly better in this group (P<0.0001), image quality was at least diagnostic in all finished examinations in natural sleep, and the functional analyzability was given in all completed examinations. There was a significant saving in examination time during natural sleep (P<0.001).

Conclusion

Functional MR urography can be successfully performed in natural sleep in infants younger than 10 months.

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Title: Functional magnetic resonance urography in infants: feasibility of a feed-and-sleep technique
Authors: Ilias Tsiflikas
Florian Obermayr
Sebastian Werner
Matthias Teufel
Jörg Fuchs
Jürgen F. Schäfer
Publication date: 01-03-2019
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 3/2019
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-018-4307-5

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Functional magnetic resonance urography in infants: feasibility of a feed-and-sleep technique

Abstract

Background

Objective

Materials and methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Objective

Materials and methods

Results

Conclusion

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