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Pediatric Radiology

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Open Access 01-03-2016 | Original Article

Erosion or normal variant? 4-year MRI follow-up of the wrists in healthy children

Authors: Derk F. M. Avenarius, Lil-Sofie Ording Müller, Karen Rosendahl

Published in: Pediatric Radiology | Issue 3/2016

Abstract

Background

A large proportion of healthy children have wrist changes on MRI, namely carpal depressions, findings that have been described as pathological in children with juvenile idiopathic arthritis.

Objective

We performed follow-up imaging in a cohort of healthy children to evaluate carpal surface depressions over time, focusing on the presence of overlying cartilage as a potential discriminator between normal variants and true erosions.

Materials and methods

74 of the initial cohort of 89 healthy children (83%) had a re-scan of their wrists using the same protocol, including coronal T1 and fat-saturated T2 sequences. A cartilage-selective sequence was added for this study. We registered number and location of bony depressions and presence of overlying cartilage.

Results

The total number of carpal depressions increased by age group and over time; their location was unchanged in 370 of 487 (76%) carpal sites and 91 of 117 (78%) metacarpal sites. In total, 426 of the 1,087 (39.2%) bony depressions were covered by cartilage, with a decreasing percentage by age (P = 0.001).

Conclusion

Normal appearances during growth, such as bony depressions, should not be mistaken for pathology. There must be additional findings to support a diagnosis of disease. A cartilage sequence may add to the diagnostic image analysis.

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Title: Erosion or normal variant? 4-year MRI follow-up of the wrists in healthy children
Authors: Derk F. M. Avenarius
Lil-Sofie Ording Müller
Karen Rosendahl
Publication date: 01-03-2016
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 3/2016
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-015-3494-6

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Erosion or normal variant? 4-year MRI follow-up of the wrists in healthy children

Abstract

Background

Objective

Materials and methods

Results

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Objective

Materials and methods

Results

Conclusion

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