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Pediatric Radiology
Published in: Pediatric Radiology 12/2015

01-11-2015 | Review

Shedding light on inflammatory pseudotumor in children: spotlight on inflammatory myofibroblastic tumor

Authors: Lillian M. Lai, M. Beth McCarville, Patricia Kirby, Simon C. S. Kao, Toshio Moritani, Eve Clark, Kousei Ishigami, Armita Bahrami, Yutaka Sato

Published in: Pediatric Radiology | Issue 12/2015

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Abstract

Inflammatory pseudotumor is a generic term used to designate a heterogeneous group of inflammatory mass-forming lesions histologically characterized by myofibroblastic proliferation with chronic inflammatory infiltrate. Inflammatory pseudotumor is multifactorial in etiology and generally benign, but it is often mistaken for malignancy given its aggressive appearance. It can occur throughout the body and is seen in all age groups. Inflammatory pseudotumor has been described in the literature by many organ-specific names, resulting in confusion. Recently within this generic category of inflammatory pseudotumor, inflammatory myofibroblastic tumor has emerged as a distinct entity and is now recognized as a fibroblastic/myofibroblastic neoplasm with intermediate biological potential and occurring mostly in children. We present interesting pediatric cases of inflammatory myofibroblastic tumors given this entity’s tendency to occur in children. Familiarity and knowledge of the imaging features of inflammatory pseudotumor can help in making an accurate diagnosis, thereby avoiding unnecessary radical surgery.
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Metadata
Title
Shedding light on inflammatory pseudotumor in children: spotlight on inflammatory myofibroblastic tumor
Authors
Lillian M. Lai
M. Beth McCarville
Patricia Kirby
Simon C. S. Kao
Toshio Moritani
Eve Clark
Kousei Ishigami
Armita Bahrami
Yutaka Sato
Publication date
01-11-2015
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 12/2015
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-015-3360-6

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