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Pediatric Radiology
Published in: Pediatric Radiology 7/2014

01-07-2014 | Case Report

Thymoma with osseous metaplasia in an adolescent

Authors: Shannon G. Farmakis, Thomas E. Herman, Marilyn J. Siegel

Published in: Pediatric Radiology | Issue 7/2014

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Abstract

A 13-year-old girl was incidentally found to have a partially calcified anterior mediastinal mass during the work-up for a left humeral lesion. The resected specimen demonstrated a lymphocyte predominant World Health Organization type B1 thymoma with nodules of metaplastic bone consistent with osseous metaplasia. In addition, she had multiple osteochondromas, a periosteal chondroma of the humerus, a metaplastic osseous pseudotumor of the thigh, and other benign-appearing sclerotic foci, all manifestations of what is likely an autosomal dominant disorder.
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Liang X, Lovell M, Capocelli K et al (2010) Thymoma in children: report of 2 cases and review of the literature. Pediatr Dev Pathol 13:202–208PubMedCrossRef
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Lakatos K, Herbrüggen H, Pötschger U et al (2013) Radiological features of thymic langerhans cell histiocytosis. Pediatr Blood Cancer 60:E143–E145PubMedCrossRef
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Rosado-de-Christenson ML, Templeton PA, Moran CA (1992) From the archives of the AFIP: Mediastinal. Radiographics 12:1013–1030
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Funai K, Yokose T, Yoshida J et al (2001) Thymoma with osseous metaplasia. J Comput Assist Tomogr 25:897–899PubMedCrossRef
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Siraj F, Jain D (2011) Invasive thymoma with osseous metaplasia and cystic change in a case of myasthenia gravis: a rare presentation. Gen Thorac Cardiovasc Surg 59:583–586PubMedCrossRef
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Metadata
Title
Thymoma with osseous metaplasia in an adolescent
Authors
Shannon G. Farmakis
Thomas E. Herman
Marilyn J. Siegel
Publication date
01-07-2014
Publisher
Springer Berlin Heidelberg
Published in
Pediatric Radiology / Issue 7/2014
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-013-2865-0

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