Top

Published in:

01-09-2013 | Case Report

Diffusion-weighted imaging to assess treatment response in a child with trilateral retinoblastoma

Authors: Gregory A. Bonci, Marc K. Rosenblum, Stephen W. Gilheeney, Ira J. Dunkel, Andrei I. Holodny

Published in: Pediatric Radiology | Issue 9/2013

Abstract

Trilateral retinoblastoma (TRb) is a rare condition in which children with bilateral retinoblastoma develop primary midline intracranial neuroblastic tumors. The intracranial lesions are difficult to follow after treatment due to residual mass-like enhancement that may represent persistent tumor or treated disease. We highlight a case where close evaluation of diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADC) characteristics accurately depicted the extent of treated disease versus residual tumor after chemotherapy.

Beck Popovic M, Balmer A, Maeder P et al (2006) Benign pineal cysts in children with bilateral retinoblastoma: a new variant of trilateral retinoblastoma? Pediatr Blood Cancer 46:755–761PubMedCrossRef

Kivela T (1999) Trilateral retinoblastoma: a meta-analysis of hereditary retinoblastoma associated with primary ectopic intracranial retinoblastoma. J Clin Oncol 17:1829–1837PubMed

Rodjan F, de Graaf P, Brisse HJ et al (2012) Trilateral retinoblastoma: neuroimaging characteristics and value of routine brain screening on admission. J Neurooncol 109:535–544PubMedCrossRef

Wright KD, Qaddoumi I, Patay Z et al (2010) Successful treatment of early detected trilateral retinoblastoma using standard infant brain tumor therapy. Pediatr Blood Cancer 55:570–572PubMedCrossRef

Provenzale JM, Mukundan S, Barboriak DP (2006) Diffusion-weighted and perfusion MR imaging for brain tumor characterization and assessment of treatment response. Radiology 239:632–649PubMedCrossRef

Erdem E, Zimmerman RA, Haselgrove JC et al (2001) Diffusion-weighted imaging and fluid attenuated inversion recovery imaging in the evaluation of primitive neuroectodermal tumors. Neuroradiology 43:927–933PubMedCrossRef

de Graaf P, Pouwels PJ, Rodjan F et al (2012) Single-shot turbo spin-echo diffusion-weighted imaging for retinoblastoma: initial experience. AJNR Am J Neuroradiol 33:110–118PubMedCrossRef

Hein PA, Eskey CJ, Dunn JF et al (2004) Diffusion-weighted imaging in the follow-up of treated high-grade gliomas: tumor recurrence versus radiation injury. AJNR Am J Neuroradiol 25:201–209PubMed

Title: Diffusion-weighted imaging to assess treatment response in a child with trilateral retinoblastoma
Authors: Gregory A. Bonci
Marc K. Rosenblum
Stephen W. Gilheeney
Ira J. Dunkel
Andrei I. Holodny
Publication date: 01-09-2013
Publisher: Springer Berlin Heidelberg
Published in: Pediatric Radiology / Issue 9/2013
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-013-2662-9

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Diffusion-weighted imaging to assess treatment response in a child with trilateral retinoblastoma

Abstract

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Please log in to get access to this content

Other articles of this Issue 9/2013

Comparison of respiratory-triggered 3-D fast spin-echo and single-shot fast spin-echo radial slab MR cholangiopancreatography images in children

MRI diffusion-weighted imaging (DWI) in pediatric small bowel Crohn disease: correlation with MRI findings of active bowel wall inflammation

Creation of a percutaneous mesocaval shunt to control variceal bleeding in a child

Comparison of radiation dose estimates, image noise, and scan duration in pediatric body imaging for volumetric and helical modes on 320-detector CT and helical mode on 64-detector CT

Effective dose estimation for pediatric upper gastrointestinal examinations using an anthropomorphic phantom set and metal oxide semiconductor field-effect transistor (MOSFET) technology

Scintigraphic features of duplex kidneys on DMSA renal cortical scans