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Published in:

01-01-2012 | Original Article

US-guided percutaneous needle biopsy of anterior mediastinal masses in children

Authors: Luke McCrone, Sarah Alexander, Cengiz Karsli, Glenn Taylor, Joao G. Amaral, Dimitri Parra, Michael Temple, Philip John, Bairbre L. Connolly

Published in: Pediatric Radiology | Issue 1/2012

Abstract

Background

Anterior mediastinal masses in children are clinically challenging, requiring prompt histological diagnosis.

Objective

The purpose of this study was to review the experience with US-guided percutaneous core needle biopsy (PCNB) of anterior mediastinal masses in children, particularly with respect to safety and diagnostic accuracy.

Materials and methods

We retrospectively reviewed the clinical presentation, imaging, sedation approach, procedural details and pathology results of US-guided PCNB of mediastinal masses that occurred during an 8-year period (2001–2008). Complications were graded and pathology was categorized into four groups based on adequacy and diagnostic yield.

Results

32 US-guided PCNBs were performed on 32 children, mean age 12 years (range 18 months to 17 years), mean weight 48 kg (range 11.5 to 109 kg, median 49 kg). A coaxial US-guided technique was used, with a mean of 8.2 passes and a mean 7.6 cores obtained (range 2–15). There were no major complications. The biopsies were adequate in volume and quality of specimens in 29/32, and 25/32 were diagnostic. PCNB was diagnostic in all cases of non-Hodgkin disease.

Conclusions

Experience with anterior mediastinal masses suggests that US-guided PCNB can be considered a viable, safe and accurate method of reaching a diagnosis in the pediatric population.

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Title: US-guided percutaneous needle biopsy of anterior mediastinal masses in children
Authors: Luke McCrone
Sarah Alexander
Cengiz Karsli
Glenn Taylor
Joao G. Amaral
Dimitri Parra
Michael Temple
Philip John
Bairbre L. Connolly
Publication date: 01-01-2012
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 1/2012
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-011-2204-2

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

US-guided percutaneous needle biopsy of anterior mediastinal masses in children

Abstract

Background

Objective

Materials and methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Objective

Materials and methods

Results

Conclusions

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