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Open Access 01-01-2012 | Review

Guidelines for imaging retinoblastoma: imaging principles and MRI standardization

Authors: Pim de Graaf, Sophia Göricke, Firazia Rodjan, Paolo Galluzzi, Philippe Maeder, Jonas A. Castelijns, Hervé J. Brisse, on behalf of the European Retinoblastoma Imaging Collaboration (ERIC)

Published in: Pediatric Radiology | Issue 1/2012

Abstract

Retinoblastoma is the most common intraocular tumor in children. The diagnosis is usually established by the ophthalmologist on the basis of fundoscopy and US. Together with US, high-resolution MRI has emerged as an important imaging modality for pretreatment assessment, i.e. for diagnostic confirmation, detection of local tumor extent, detection of associated developmental malformation of the brain and detection of associated intracranial primitive neuroectodermal tumor (trilateral retinoblastoma). Minimum requirements for pretreatment diagnostic evaluation of retinoblastoma or mimicking lesions are presented, based on consensus among members of the European Retinoblastoma Imaging Collaboration (ERIC). The most appropriate techniques for imaging in a child with leukocoria are reviewed. CT is no longer recommended. Implementation of a standardized MRI protocol for retinoblastoma in clinical practice may benefit children worldwide, especially those with hereditary retinoblastoma, since a decreased use of CT reduces the exposure to ionizing radiation.

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Title: Guidelines for imaging retinoblastoma: imaging principles and MRI standardization
Authors: Pim de Graaf
Sophia Göricke
Firazia Rodjan
Paolo Galluzzi
Philippe Maeder
Jonas A. Castelijns
Hervé J. Brisse
on behalf of the European Retinoblastoma Imaging Collaboration (ERIC)
Publication date: 01-01-2012
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 1/2012
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-011-2201-5

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