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Pediatric Radiology
Published in: Pediatric Radiology 7/2011

01-07-2011 | Original Article

Individualized volume CT dose index determined by cross-sectional area and mean density of the body to achieve uniform image noise of contrast-enhanced pediatric chest CT obtained at variable kV levels and with combined tube current modulation

Author: Hyun Woo Goo

Published in: Pediatric Radiology | Issue 7/2011

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Abstract

Background

A practical body-size adaptive protocol providing uniform image noise at various kV levels is not available for pediatric CT.

Objective

To develop a practical contrast-enhanced pediatric chest CT protocol providing uniform image noise by using an individualized volume CT dose index (CTDIvol) determined by the cross-sectional area and density of the body at variable kV levels and with combined tube current modulation.

Materials and methods

A total of 137 patients (mean age, 7.6 years) underwent contrast-enhanced pediatric chest CT based on body weight. From the CTDIvol, image noise, and area and mean density of the cross-section at the lung base in the weight-based group, the best fit equation was estimated with a very high correlation coefficient (γ2 = 0.86, P < 0.001). For the next study, 177 patients (mean age, 7.9 years; the CTDIvol group) underwent contrast-enhanced pediatric chest CT with the CTDIvol determined individually by the best fit equation. CTDIvol values on the dose report after CT scanning, noise differences from the target noise, areas, and mean densities were compared between these two groups.

Results

The CTDIvol values (mean±standard deviation, 1.6 ± 0.7 mGy) and the noise differences from the target noise (1.1 ± 0.9 HU) of the CTDIvol group were significantly lower than those of the weight-based group (2.0 ± 1.0 mGy, 1.8 ± 1.4 HU) (P < 0.001). In contrast, no statistically significant difference was found in area (317.0 ± 136.8 cm2 vs. 326.3 ± 124.8 cm2), mean density (−212.9 ± 53.1 HU vs. −221.1 ± 56.3 HU), and image noise (13.8 ± 2.3 vs. 13.6 ± 1.7 HU) between the weight-based and the CTDIvol groups (P > 0.05).

Conclusion

Contrast-enhanced pediatric chest CT with the CTDIvol determined individually by the cross-sectional area and density of the body provides more uniform noise and better dose adaptation to body habitus than does weight-based CT at variable kV levels and with combined tube current modulation.
Literature
1.
Kalra MK, Maher MM, Toth TL et al (2004) Strategies for CT radiation dose optimization. Radiology 230:619–628PubMedCrossRef
2.
Goo HW (2005) Pediatric CT: understanding of radiation dose and optimization of imaging techniques. J Korean Radiol Soc 52:1–5
3.
Yang DH, Goo HW (2008) Pediatric 16-slice CT protocols: radiation dose and image quality. J Korean Radiol Soc 59:333–347
4.
Singh S, Kalra MK, Moore MA et al (2009) Dose reduction and compliance with pediatric CT protocols adapted to patient size, clinical indication, and number of prior studies. Radiology 252:200–208PubMedCrossRef
5.
Stark G, Lonn L, Cederblad A et al (2002) A method to obtain the same levels of CT image noise for patients with various sizes, to minimize radiation dose. Br J Radiol 75:140–150
6.
Boone JM, Geraphty EM, Seibert JA et al (2003) Dose reduction in pediatric CT: a rational approach. Radiology 228:352–360PubMedCrossRef
7.
Kalra MK, Maher MM, Prasad SR et al (2003) Correlation of patient weight and cross-sectional dimensions with subjective image quality at standard dose abdominal CT. Korean J Radiol 4:234–238PubMedCrossRef
8.
Jung YY, Goo HW (2008) The optimal parameter for radiation dose in pediatric low dose abdominal CT: cross-sectional dimensions versus body weight. J Korean Radiol Soc 58:169–175
9.
Nyman U, Ahl TL, Kristiansson M et al (2005) Patient-circumference-adapted dose regulation in body computed tomography. A practical and flexible formula. Acta Radiol 46:396–406PubMedCrossRef
10.
Menke J (2005) Comparison of different body size parameters for individual dose adaptation in body CT of adults. Radiology 236:565–571PubMedCrossRef
11.
Irie T, Inoue H (2005) Individual modulation of the tube current-seconds to achieve similar levels of image noise in contrast-enhanced abdominal CT. AJR Am J Roentgenol 184:1514–1518PubMed
12.
Hur G, Hong SW, Kim SY et al (2007) Uniform image quality achieved by tube current modulation using SD of attenuation in coronary CT angiography. AJR Am J Roentgenol 189:188–196PubMedCrossRef
13.
Goo HW, Suh DS (2006) Tube current reduction in pediatric non-ECG-gated heart CT by combined tube current modulation. Pediatr Radiol 36:344–351PubMedCrossRef
14.
Goo HW, Suh DS (2006) The influences of tube voltage and scan direction on combined tube current modulation: a phantom study. Pediatr Radiol 36:833–840PubMedCrossRef
15.
Schindera ST, Nelson RC, Toth TL et al (2008) Effect of patient size on radiation dose for abdominal MDCT with automatic tube current modulation: phantom study. AJR Am J Roentgenol 190:W100–W105PubMedCrossRef
16.
17.
18.
Prakash P, Kalra MK, Gilman MD et al (2010) Is weight-based adjustment of automatic exposure control necessary for the reduction of chest CT radiation dose? Korean J Radiol 11:46–53PubMedCrossRef
19.
Watanabe H, Kanematsu M, Miyoshi T et al (2010) Improvement of image quality of low radiation dose abdominal CT by increasing contrast enhancement. AJR Am J Roentgenol 195:986–992PubMedCrossRef
20.
Yu L, Li H, Fletcher JG et al (2010) Automatic selection of tube potential for radiation dose reduction in CT: a general strategy. Med Phys 37:234–243PubMedCrossRef
Metadata
Title
Individualized volume CT dose index determined by cross-sectional area and mean density of the body to achieve uniform image noise of contrast-enhanced pediatric chest CT obtained at variable kV levels and with combined tube current modulation
Author
Hyun Woo Goo
Publication date
01-07-2011
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 7/2011
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-011-2121-4

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