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Pediatric Radiology
Published in: Pediatric Radiology 11/2008

01-11-2008 | Case Report

Transient isolated lesion of the splenium associated with clinically mild influenza encephalitis

Authors: Srinivas Ganapathy, Elizabeth H. Ey, Barbara J. Wolfson, Nadir Khan

Published in: Pediatric Radiology | Issue 11/2008

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Abstract

Transient isolated lesions of the splenium with restricted diffusion are rare in the pediatric population. We report two such cases with influenza-associated encephalitis/encephalopathy (IAEE). These reversible isolated central splenial lesions are not specific for IAEE, but the notable feature associated with this specific presentation is a comparatively milder form of encephalitis that resolves clinically and radiologically within a short time.
Literature
1.
Bulakbasi N, Kocaoglu M, Tayfun C et al (2006) Transient splenial lesion of the corpus callosum in clinically mild influenza-associated encephalitis/encephalopathy. AJNR 27:1983–1986PubMed
2.
Takanashi J, Barkovich AJ, Yamaguchi K et al (2004) Influenza encephalopathy with a reversible lesion in the splenium of the corpus callosum. AJNR 25:798–802PubMed
3.
Tada H, Takanashi J, Barkovich AJ et al (2004) Clinically mild encephalitis/encephalopathy with a reversible splenial lesion. Neurology 63:1854–1858PubMed
4.
Matsukara K, Kodera M, Nigami H et al (2007) Reversible splenial lesion in influenza virus encephalopathy. Pediatr Neurol 6:431–434CrossRef
5.
Ritsuyo K, Hirokazu T, Akio N et al (2002) Transient MR signal changes in the splenium of the corpus callosum in rotavirus encephalopathy: value of diffusion-weighted imaging. J Comput Assist Tomogr 26:825–828CrossRef
6.
Kobuchi N, Tsukahara H, Kawamura Y et al (2003) Reversible diffusion weighted MR findings of Salmonella enteritidis-associated encephalopathy. Eur Neurol 49:182–184PubMedCrossRef
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Kim SS, Chang K-H, Kim ST et al (1999) Focal lesion in the splenium of the corpus callosum in epileptic patients: antiepileptic drug toxicity? AJNR 20:125–129PubMed
8.
Takanashi J, Barkovich AJ, Shiihara T et al (2006) Widening spectrum of a reversible splenial lesion with transiently reduced diffusion. AJNR 27:836–838PubMed
Metadata
Title
Transient isolated lesion of the splenium associated with clinically mild influenza encephalitis
Authors
Srinivas Ganapathy
Elizabeth H. Ey
Barbara J. Wolfson
Nadir Khan
Publication date
01-11-2008
Publisher
Springer-Verlag
Published in
Pediatric Radiology / Issue 11/2008
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI
https://doi.org/10.1007/s00247-008-0949-z

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