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01-09-2008 | Original Article

MRI of the fetal eyes: morphologic and biometric assessment for abnormal development with ultrasonographic and clinicopathologic correlation

Authors: Ashley J. Robinson, Susan Blaser, Ants Toi, David Chitayat, Sophie Pantazi, Sarah Keating, Sandra Viero, Greg Ryan

Published in: Pediatric Radiology | Issue 9/2008

Abstract

Background

Currently ocular biometric measurements are defined by US and are measured from the orbital walls. These bony landmarks cannot be seen by MRI, and therefore these measurements cannot be directly applied.

Objective

To define measurements of normal growth of the fetal eyes using MRI.

Materials and methods

Transorbital views were analyzed in 198 fetal MR examinations. The ocular diameter (OD) and interocular and binocular distances (IOD and BOD) were measured and were plotted against gestational age. Fetuses with abnormalities affecting the eyes were evaluated separately.

Results

Of 198 scans, 146 had suitable images, 35 of which were abnormal. Normal growth of BOD, IOD and OD were determined, and compared with the respective already established US data.

Conclusion

Normal growth charts were derived from a cohort of 111 normal fetuses. Because the margins of the vitreous are inside the bony orbit, at the same gestational age measurements of the BOD and OD are always less than the corresponding measurements by US, and those of the IOD are always more. Normal growth charts for MRI can now be used to support suspected diagnoses of orbital and ocular pathologies and the syndromes that give rise to them, and many examples are demonstrated.

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Title: MRI of the fetal eyes: morphologic and biometric assessment for abnormal development with ultrasonographic and clinicopathologic correlation
Authors: Ashley J. Robinson
Susan Blaser
Ants Toi
David Chitayat
Sophie Pantazi
Sarah Keating
Sandra Viero
Greg Ryan
Publication date: 01-09-2008
Publisher: Springer-Verlag
Published in: Pediatric Radiology / Issue 9/2008
Print ISSN: 0301-0449
Electronic ISSN: 1432-1998
DOI: https://doi.org/10.1007/s00247-008-0929-3

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Springer Medicine

MRI of the fetal eyes: morphologic and biometric assessment for abnormal development with ultrasonographic and clinicopathologic correlation

Abstract

Background

Objective

Materials and methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Objective

Materials and methods

Results

Conclusion

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